Richard M Palmer

..With the increase in numbers of patients treated there will be greater demands to provide this care in general practices...

..To review the scientific preclinical background and clinical studies of current methods of periodontal regeneration in the treatment of infrabony defects and soft tissue deficiencies...

..Clinicians involved in these treatments must obtain adequate training and develop skills through treatment of straightforward cases using well established protocols before embarking on more demanding cases...

..Key neutrophil effector functions (oxidative burst, bacterial killing, matrix metalloproteinase release) were also examined...

..Connecting teeth and osseointegrated implants in fixed reconstructions is not generally recommended because of differences in their response to loading...

..To evaluate the use of a single Astra Tech implant to support a two-unit cantilever fixed dental prosthesis...

..To investigate patient centred outcomes, soft tissue morphology, and bone levels...

..To review the potential biological mechanisms underlying the effects of tobacco smoking on periodontitis...

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..We have previously shown that systemic concentrations of these molecules are increased significantly in tobacco smokers, but reduce to within normal levels at 12 months following successful quitting...

..Patients additionally completed the GHQ 2 years after overdenture insertion...

..CONCLUSION: The overall pattern of tissue destruction was consistent with a systemic effect of smoking. The suggestion of a marginal local effect of the smoking habit in maxillary anterior palatal sites requires further investigation...

..Rapid treatment protocols can be considered when they do not compromise these goals, and the clinician is sufficiently experienced in their application...

..A number of studies have suggested that implant failure and associated bone loss is greater in subjects with a history of periodontitis...

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..To assess the accuracy of measuring the cortical bone thickness adjacent to dental implants using two cone beam computed tomography (CBCT) systems...

..8 +/- 11.5 pg/ml at day 5). The same pattern was observed with the IL-6, IL-18, and OPG with polystyrene appearing to stimulate most production of OPG. Titanium-aluminium-vanadium produced the least biological response...

..To measure the effect of three special liquid proportions and five forming temperatures on the length of superplastically formed titanium dental implant superstructures made using Rematitan dental casting investment...

..These observations may be relevant to aetiological mechanisms in periodontitis and other smoking-associated diseases...

..Soluble ICAM-1 remains bioactive and may contribute to pathogenic processes; therefore, reduction in the concentration of circulating ICAM-1 molecules may directly contribute to the health benefits associated with smoking cessation...

..Reduced ICAM-1 expression in non-inflamed areas of smokers could reflect a systemic effect of tobacco smoking on ICAM-1 independent of inflammation...

..The aim of this study was to investigate the transfer of bacterial doxycycline resistance between oral bacteria in subjects receiving systemic doxycycline for the treatment of periodontitis...

..001). Since GCF is a serum-derived tissue exudate, these results suggest that, in smokers, circulating sICAM-1 molecules are affected either in their passage from the periodontal microvasculature or within the periodontal tissues...

..To evaluate the AstraTech Implant ST (Molndal, Sweden) for single tooth replacement clinically and radiographically after 5 years in function...

..This has led to the recovery of 'unculturables' from soil and aquatic environments, likely to be due to the inclusion of essential nutrients and/or signalling molecules from the native environment...

..Rinsing with ethanol-containing mouthrinses causes a rapid, but transient, increase in salivary acetaldehyde levels...

..In conclusion, the single tooth Astra implants were highly successful and bone changes within the first 2 years of function were comparable with other systems reporting high long-term success rates...

..CONCLUSION: This provides further evidence that tobacco smoking affects the inflammatory response and that these changes are reversible on quitting...

..To assess the management of patients who are current smokers in dental practice...

..However, little focus has been placed on the impact of smoking on bone regeneration after treatment. The aim of this review is to systematically assess the effect of smoking on bone regeneration after periodontal treatment...

..Their role in human disease has yet to be established but improved knowledge of the characteristics that enable their identification should increase the likelihood of their recognition when present at diseased sites...

..This may be partly explained by the reduced inflammation and width of supra-bony connective tissue in smokers. These findings have clinical relevance to the successful management of periodontal patients who smoke...

..To investigate the orthodontic management of patients with developmentally absent maxillary lateral incisors...

..A combination of molecular and cultural techniques is recommended to maximise the coverage of detection of bacterial taxa in oral samples...

..This is the first report of the successful culture of a member of the uncultivable branch of this phylum...

..To determine whether adjunctive metronidazole therapy would compensate for the poorer treatment response to scaling and root planing reported in smokers...

..In addition, the influence of gender, smoking and the number of years without natural teeth were examined...