V Kumari

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophrenia
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, King s College London, London SE5 8AF, United Kingdom
    Behav Brain Res 193:132-9. 2008
  2. ncbi Neurological basis of poor insight in psychosis: a voxel-based MRI study
    Michael A Cooke
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 103:40-51. 2008
  3. ncbi Structural magnetic resonance imaging predictors of responsiveness to cognitive behaviour therapy in psychosis
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 115:146-55. 2009
  4. ncbi Insight, distress and coping styles in schizophrenia
    Michael Cooke
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 94:12-22. 2007
  5. ncbi Cognitive insight in psychosis: the relationship between self-certainty and self-reflection dimensions and neuropsychological measures
    Michael A Cooke
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Psychiatry Res 178:284-9. 2010
  6. ncbi Lack of association between prepulse inhibition and antisaccadic deficits in chronic schizophrenia: implications for identification of schizophrenia endophenotypes
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    J Psychiatr Res 39:227-40. 2005
  7. ncbi Cognitive effects of nicotine in humans: an fMRI study
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College, London, UK
    Neuroimage 19:1002-13. 2003
  8. ncbi Functional MRI of verbal self-monitoring in schizophrenia: performance and illness-specific effects
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 36:740-55. 2010
  9. ncbi Evidence for a role of progesterone in menstrual cycle-related variability in prepulse inhibition in healthy young women
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:929-37. 2010
  10. ncbi Cortical grey matter volume and sensorimotor gating in schizophrenia
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Cortex 44:1206-14. 2008

Detail Information

Publications101 found, 100 shown here

  1. ncbi Association between a longer duration of illness, age and lower frontal lobe grey matter volume in schizophrenia
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, King s College London, London SE5 8AF, United Kingdom
    Behav Brain Res 193:132-9. 2008
    ..The effect of illness chronicity on GM volume in the left dorsomedial PFC may be extended to brain structure-neuropsychological function relationships...
  2. ncbi Neurological basis of poor insight in psychosis: a voxel-based MRI study
    Michael A Cooke
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 103:40-51. 2008
    ..As a reflection of poor insight, people with schizophrenia often disagree with carers and clinicians about whether (a) their experiences are abnormal, (b) they are mentally ill, and (c) they need treatment...
  3. ncbi Structural magnetic resonance imaging predictors of responsiveness to cognitive behaviour therapy in psychosis
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 115:146-55. 2009
    ..This study aimed to determine whether improvement in symptoms following CBT for psychosis (CBTp) in people with schizophrenia is positively associated with pre-therapy grey matter volume in brain regions involved in cognitive processing...
  4. ncbi Insight, distress and coping styles in schizophrenia
    Michael Cooke
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 94:12-22. 2007
    ..There is evidence that poor insight into symptoms of the disorder and need for treatment may reflect the use of denial as a coping style. However, the relationships between insight and other coping styles have seldom been investigated...
  5. ncbi Cognitive insight in psychosis: the relationship between self-certainty and self-reflection dimensions and neuropsychological measures
    Michael A Cooke
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Psychiatry Res 178:284-9. 2010
    ..The self-certainty and self-reflection dimensions of cognitive insight have differential correlates, and probably different mechanisms, in psychosis...
  6. ncbi Lack of association between prepulse inhibition and antisaccadic deficits in chronic schizophrenia: implications for identification of schizophrenia endophenotypes
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    J Psychiatr Res 39:227-40. 2005
    ..It is concluded that PPI and antisaccade abnormalities in schizophrenia represent separate endophenotypes, reflecting the functions of different genetic aetiologies and different or only partially overlapping neural systems...
  7. ncbi Cognitive effects of nicotine in humans: an fMRI study
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College, London, UK
    Neuroimage 19:1002-13. 2003
    ....
  8. ncbi Functional MRI of verbal self-monitoring in schizophrenia: performance and illness-specific effects
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Bull 36:740-55. 2010
    ..Altered striatal and hypothalamic modulation to own and others' voice characterizes emotionally withdrawn and socially avoidant patients...
  9. ncbi Evidence for a role of progesterone in menstrual cycle-related variability in prepulse inhibition in healthy young women
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Neuropsychopharmacology 35:929-37. 2010
    ....
  10. ncbi Cortical grey matter volume and sensorimotor gating in schizophrenia
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Cortex 44:1206-14. 2008
    ....
  11. ncbi Neural and behavioural responses to threat in men with a history of serious violence and schizophrenia or antisocial personality disorder
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 110:47-58. 2009
    ..This study examined behavioural and brain abnormalities in violent men with schizophrenia or APD during anticipatory fear...
  12. ncbi Sex differences in prepulse inhibition deficits in chronic schizophrenia
    Veena Kumari
    Department of Psychology Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 69:219-35. 2004
    ..Future studies of schizophrenia patients need to take sex and age of subjects into account to optimise the investigation of PPI deficits, and their clinical, neural, and pharmacological correlates...
  13. ncbi Neural correlates of adjunctive rivastigmine treatment to antipsychotics in schizophrenia: a randomized, placebo-controlled, double-blind fMRI study
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Neuroimage 29:545-56. 2006
    ....
  14. ncbi Structural brain correlates of prepulse inhibition of the acoustic startle response in healthy humans
    Veena Kumari
    Department of Psychology, PO78, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Neuroimage 26:1052-8. 2005
    ....
  15. ncbi Nicotine use in schizophrenia: the self medication hypotheses
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, London SE5 8AF, UK
    Neurosci Biobehav Rev 29:1021-34. 2005
    ....
  16. ncbi Dorsolateral prefrontal cortex activity predicts responsiveness to cognitive-behavioral therapy in schizophrenia
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, United Kingdom
    Biol Psychiatry 66:594-602. 2009
    ....
  17. ncbi Dysfunctional, but not functional, impulsivity is associated with a history of seriously violent behaviour and reduced orbitofrontal and hippocampal volumes in schizophrenia
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Psychiatry Res 173:39-44. 2009
    ..Violence risk prediction and management strategies in schizophrenia may benefit from including specific measures of dysfunctional impulsive traits...
  18. ncbi Association between violent behaviour and impaired prepulse inhibition of the startle response in antisocial personality disorder and schizophrenia
    Veena Kumari
    Department of Psychology, PO78, Institute of Psychiatry, Kings College London, De Crespigny Park, London SE5 8AF, UK
    Behav Brain Res 158:159-66. 2005
    ..The association between violent behaviour and impaired PPI suggests that neural structures and functions underlying PPI are implicated in (inhibition of) violence...
  19. ncbi Reduced prepulse inhibition in unaffected siblings of schizophrenia patients
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Psychophysiology 42:588-94. 2005
    ..High schizotypal ratings were mildly associated with reduced prepulse inhibition. Prepulse inhibition may provide a useful measure in the search for schizophrenia genes...
  20. ncbi Personality predicts brain responses to cognitive demands
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    J Neurosci 24:10636-41. 2004
    ..These observations suggest that individual differences affect brain responses during cognitive activity and at rest and provide evidence for the hypothesized neurobiological basis of personality...
  21. ncbi Neural correlates of tactile prepulse inhibition: a functional MRI study in normal and schizophrenic subjects
    Veena Kumari
    Section of Cognitive Psychopharmacology, Institute of Psychiatry, King s College, De Crespigny Park, London SE5 8AF, UK
    Psychiatry Res 122:99-113. 2003
    ..The findings demonstrate involvement of the striatum, hippocampus, thalamus, and frontal and parietal cortical regions in PPI. Dysfunctions in any of these regions may underlie observations of reduced PPI in schizophrenia...
  22. ncbi Effects of d-amphetamine and haloperidol on latent inhibition in healthy male volunteers
    V Kumari
    Department of Psychology, Institute of Psychiatry, London, UK
    J Psychopharmacol 13:398-405. 1999
    ..In a subsequent study, no effect was found of 2 mg oral haloperidol administration on LI. The effect of 5 mg haloperidol on LI is interpreted as similar to that observed with a high dose of haloperidol in rats...
  23. ncbi Neuroticism and brain responses to anticipatory fear
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
    Behav Neurosci 121:643-52. 2007
    ..The observations support recent psychophysiological research that has demonstrated reduced processing of pain in subjects with higher levels of neuroticism, especially the anxiety component of this trait...
  24. ncbi Enhanced startle reactions to acoustic stimuli in patients with obsessive-compulsive disorder
    V Kumari
    Departments of Psychology and Psychiatry, Institute of Psychiatry, London, UK
    Am J Psychiatry 158:134-6. 2001
    ..The authors investigated whether patients with obsessive-compulsive disorder (OCD) show exaggerated startle reactions to acoustic probes, especially during negative-affect-toned stimuli, compared with healthy subjects...
  25. ncbi Effects of acute procyclidine administration on prepulse inhibition of the startle response in schizophrenia: a double-blind, placebo-controlled study
    Veena Kumari
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
    J Psychopharmacol 17:89-95. 2003
    ..The use of anticholinergics needs to be carefully controlled/examined in investigations of information processing deficits using a PPI model and reduced to the minimum level in clinical care of schizophrenia...
  26. ncbi Effects of procyclidine on prepulse inhibition of the acoustic startle response in healthy human volunteers
    V Kumari
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Psychopharmacology (Berl) 154:221-9. 2001
    ..No previous study has investigated the effects of anticholinergic drugs on human PPI...
  27. ncbi Startle gating in antipsychotic-naïve first episode schizophrenia patients: one ear is better than two
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Psychiatry Res 151:21-8. 2007
    ..It is concluded that first episode schizophrenia patients show deficient sensorimotor gating but they are not impaired in the mechanism underlying stronger PPI with monaural than binaural prepulses...
  28. ncbi A comparison of prepulse inhibition in pre- and postmenopausal women and age-matched men
    Veena Kumari
    King s College London, Department of Psychology, Institute of Psychiatry, London, UK
    Neuropsychopharmacology 33:2610-8. 2008
    ..There appear to be no substantial relationships between individual differences in endogenous levels of sex hormones and PPI; fluctuations within an individual may have a stronger role...
  29. ncbi A fMRI investigation of startle gating deficits in schizophrenia patients treated with typical or atypical antipsychotics
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Int J Neuropsychopharmacol 10:463-77. 2007
    ..Imaging data buttress the validity of PPI as a useful animal model of schizophrenia...
  30. ncbi Use of magnetic resonance imaging in tracking the course and treatment of schizophrenia
    Veena Kumari
    King s College London, Institute of Psychiatry Department of Psychology, PO78, London, SE5 8AF, UK
    Expert Rev Neurother 6:1005-16. 2006
    ..Understanding the trait- and state-related influences of brain abnormalities during the course of the illness is critical for developing effective treatment and possibly prevention strategies in schizophrenia...
  31. ncbi Prepulse inhibition and "psychosis-proneness" in healthy individuals: an fMRI study
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, De Crespigny Park, London, UK
    Eur Psychiatry 23:274-80. 2008
    ....
  32. ncbi Procedural learning in schizophrenia: a functional magnetic resonance imaging investigation
    Veena Kumari
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK
    Schizophr Res 57:97-107. 2002
    ....
  33. ncbi Uncontrollable voices and their relationship to gating deficits in schizophrenia
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 101:185-94. 2008
    ..The aim of this study was to investigate PPI deficit in relation to the dimensions of auditory hallucinations in patients with schizophrenia or schizoaffective disorder...
  34. ncbi Neural dysfunction and violence in schizophrenia: an fMRI investigation
    Veena Kumari
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Schizophr Res 84:144-64. 2006
    ..It is concluded that reduced functional response in the frontal and inferior parietal regions leads to serious violence in schizophrenia perhaps via impaired executive functioning...
  35. ncbi A behavioural and functional neuroimaging investigation into the effects of nicotine on sensorimotor gating in healthy subjects and persons with schizophrenia
    Peggy Postma
    Department of Psychology, P078, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF, UK
    Psychopharmacology (Berl) 184:589-99. 2006
    ..CONCLUSIONS: Nicotine enhances tactile PPI in both healthy and schizophrenia groups. Our preliminary fMRI findings reveal that this effect is modulated by increased limbic activity...
  36. ncbi Effects of single oral administrations of haloperidol and d-amphetamine on prepulse inhibition of the acoustic startle reflex in healthy male volunteers
    V Kumari
    Section of Cognitive Psychopharmacology, University of London, UK
    Behav Pharmacol 9:567-76. 1998
    ..The implications of these findings in relation to animal pharmacological studies and observed sensorimotor gating deficits in schizophrenia are discussed...
  37. ncbi Prepulse inhibition of the startle response in risperidone-treated patients: comparison with typical antipsychotics
    Veena Kumari
    Section of Cognitive Psychopharmacology, Department of Psychiatry, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 55:139-46. 2002
    ....
  38. ncbi Cognitive functioning in siblings discordant for schizophrenia
    C Hughes
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Acta Psychiatr Scand 111:185-92. 2005
    ..This deficit appeared to be mediated by IQ. Deficits, which differentiated patients from controls, may not be inherited and perhaps are related to the manifestation or treatment of schizophrenia...
  39. ncbi The perception of real and illusory motion in schizophrenia
    T J Crawford
    Department of Psychology, Lancaster University, Mental Health and Neural Systems, Lancaster LA1 4YF, United Kingdom
    Neuropsychologia 48:3121-7. 2010
    ..The findings revealed that people with schizophrenia may be less easily deceived by illusory motion in comparison to healthy participants...
  40. ncbi The relationship of sex hormones and cortisol with cognitive functioning in Schizophrenia
    R Halari
    Centre for Social, Genetic and Developmental Psychiatry and Department of Psychology, City University, London, UK
    J Psychopharmacol 18:366-74. 2004
    ....
  41. ncbi Fronto-temporal function may distinguish bipolar disorder from schizophrenia
    S Frangou
    Section of Neurobiology of Psychosis, Institute of Psychiatry, King s Coillege London, London, UK
    Bipolar Disord 8:47-55. 2006
    ..Our objective was to compare the cognitive profile of stable BDI and schizophrenic patients using neuropsychological tasks which utilize frontal systems but differ in terms of the exact neural circuits and cognitive processes involved...
  42. ncbi Effects of procyclidine on eye movements in schizophrenia
    Ulrich Ettinger
    Division of Psychological Medicine, Institute of Psychiatry, UK
    Neuropsychopharmacology 28:2199-208. 2003
    ..Effects of order of administration and practice on the antisaccade task suggest that these factors need to be taken into consideration in future pharmacological studies...
  43. ncbi Effect of acute subcutaneous nicotine on prepulse inhibition of the acoustic startle reflex in healthy male non-smokers
    V Kumari
    Department of Psychology, University of London, UK
    Psychopharmacology (Berl) 132:389-95. 1997
    ....
  44. ncbi Comparable cortical activation with inferior performance in women during a novel cognitive inhibition task
    R Halari
    Department of Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, PO46, De Crespigny Park, London SE5 8AF, UK
    Behav Brain Res 158:167-73. 2005
    ..Equated behavioural performance may elicit sex differences in brain activation...
  45. ncbi Affective modulation of the startle response in depression: influence of the severity of depression, anhedonia, and anxiety
    H Kaviani
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    J Affect Disord 83:21-31. 2004
    ..Anxiety is associated with hyperstartle responding...
  46. ncbi Brain anatomy and sensorimotor gating in Asperger's syndrome
    Grainne M McAlonan
    Department of Psychological Medicine, Institute of Psychiatry, London, UK
    Brain 125:1594-606. 2002
    ....
  47. ncbi Prefrontal cortex and insight in schizophrenia: a volumetric MRI study
    Adegboyega Sapara
    King s College London, Institute of Psychiatry, Department of Psychology, London, UK
    Schizophr Res 89:22-34. 2007
    ..Future research should examine the association of specific dimensions of insight with frontal as well as non-frontal regional brain volumes...
  48. ncbi Startle response during smoking and 24 h after withdrawal predicts successful smoking cessation
    P Postma
    Department of Psychology, Institute of Psychiatry, London, UK
    Psychopharmacology (Berl) 156:360-7. 2001
    ..The present study examined individual differences in cognitive benefits obtained from smoking as indexed by startle response and PPI...
  49. ncbi Gender differences in immediate memory in bipolar disorder
    D Carrus
    Section of Neurobiology of Psychosis, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 40:1349-55. 2010
    ..Although cognitive abnormalities are an established feature of BD, there is limited information regarding whether gender also influences the pattern and severity of cognitive impairment...
  50. ncbi Magnetic resonance imaging of the thalamus in first-episode psychosis
    U Ettinger
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, University of London, London, UK
    Am J Psychiatry 158:116-8. 2001
    ..There were no significant correlations between thalamic volumes and symptom scores. CONCLUSIONS: Thalamic abnormalities are present close to the onset of psychosis...
  51. ncbi A longer duration of schizophrenic illness has sex-specific associations within the working memory neural network in schizophrenia
    Sarah Elsabagh
    King s College School of Medicine, King s College London, London, UK
    Behav Brain Res 201:41-7. 2009
    ..Additionally, brain regions that exhibit sexually dimorphic activation in healthy people may become compromised in the corresponding sex with illness progression...
  52. ncbi Neural correlates of deficient response inhibition in mentally disordered violent individuals
    Ian Barkataki
    Department of Psychology, School of HumanSciences, University of Surrey, Guildford GU2 7HX, UK
    Behav Sci Law 26:51-64. 2008
    ..In addition, caudate dysfunction may contribute, given its role in timing and temporal processing as well as suppression of motor actions, to deficient inhibition and violent behaviour in schizophrenia...
  53. ncbi Longitudinal study of symptoms and cognitive function in chronic schizophrenia
    Catherine Hughes
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    Schizophr Res 59:137-46. 2003
    ..The results do not suggest a causal relationship between the course of symptoms and neuropsychological functioning in chronic schizophrenia...
  54. ncbi Individual differences in mood reactions to d-amphetamine: a test of three personality factors
    P J Corr
    Department of Psychology, Goldsmiths College, University of London, New Cross, UK
    J Psychopharmacol 14:371-7. 2000
    ..It is concluded that the routine inclusion of personality measures in future psychopharmacological studies may help to refine the characterization of drug effects...
  55. ncbi Neurological soft signs and their relationship to cognitive and clinical efficacy of atypical antipsychotics in schizophrenia
    Mrigendra Das
    Institute of Psychiatry, London, UK
    Schizophr Bull 30:241-53. 2004
    ..The presence of high NSS in schizophrenia patients impedes the improvement in cognitive function with atypical antipsychotics treatment...
  56. ncbi Volumetric structural brain abnormalities in men with schizophrenia or antisocial personality disorder
    Ian Barkataki
    Division of Psychological Medicine, Institute of Psychiatry, King s College London, London, UK
    Behav Brain Res 169:239-47. 2006
    ....
  57. ncbi No gender differences in brain activation during the N-back task: an fMRI study in healthy individuals
    Heike Schmidt
    Section of Neurobiology of Psychosis, Institute of Psychiatry, King s College London, United Kingdom
    Hum Brain Mapp 30:3609-15. 2009
    ....
  58. ncbi Pilot investigation of the changes in cortical activation during facial affect recognition with lamotrigine monotherapy in bipolar disorder
    Jigar Jogia
    Section of Neurobiology of Psychosis, Institute of Psychiatry, King s College London, PO66, De Crespigny Park, London, SE5 8AF, UK
    Br J Psychiatry 192:197-201. 2008
    ..Bipolar disorder is associated with dysfunction in prefrontal and limbic areas implicated in emotional processing...
  59. ncbi N-acetyl aspartate concentration in the anterior cingulate cortex in patients with schizophrenia: a study of clinical and neuropsychological correlates and preliminary exploration of cognitive behaviour therapy effects
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, King s College London, London, United Kingdom
    Psychiatry Res 182:251-60. 2010
    ..NAA concentration may be more closely associated with symptoms and symptom change than frontal lobe based neuropsychological function in schizophrenia, perhaps because the latter is relatively stable during the long-term illness course...
  60. ncbi Insight in psychosis: influence of cognitive ability and self-esteem
    Michael A Cooke
    King s College London, Institute of Psychiatry, Department of Psychology PO77, 16 De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Br J Psychiatry 191:234-7. 2007
    ..Some studies have found a curvilinear relationship between insight and cognitive ability, but the roles of self-esteem and depression have not been taken into account...
  61. ncbi The relationship between prepulse detection and prepulse inhibition of the acoustic startle reflex
    P Postma
    Department of Psychology, Institute of Psychiatry, London, UK
    Psychophysiology 38:377-82. 2001
    ..However, trials on which detection occurred did not differ from trials without detection on measures of startle inhibition. This suggests that PPI is independent of awareness of the prepulse...
  62. ncbi Differential motivational responses to food and pleasurable cues in anorexia and bulimia nervosa: a startle reflex paradigm
    Hans Christoph Friederich
    Eating Disorders Unit, Institute of Psychiatry, King s College London, London, UK
    Psychol Med 36:1327-35. 2006
    ..SEM was used because it is sensitive to motivational states of approach (appetitive response) and withdrawal (aversive response), which are independent of conscious intentional control...
  63. ncbi Changes in brain activation during working memory and facial recognition tasks in patients with bipolar disorder with Lamotrigine monotherapy
    Morgan Haldane
    Section of Neurobiology of Psychosis, Institute of Psychiatry, PO66 De Crespigny Park London SE5 8AF, UK
    Eur Neuropsychopharmacol 18:48-54. 2008
    ..Therefore, LTG monotherapy in BD patients may enhance cortical function within neural circuits involved in memory and emotional self-regulation...
  64. ncbi Association of Neuregulin 1 rs3924999 genotype with antisaccades and smooth pursuit eye movements
    A Schmechtig
    Department of Neuroimaging, King s College Institute of Psychiatry, London, UK
    Genes Brain Behav 9:621-7. 2010
    ....
  65. ncbi Personality factors correlate with regional cerebral perfusion
    R L O'Gorman
    Department of Neuroimaging, Ground Floor, Ruskin Wing, King s College Hospital, Denmark Hill, London SE5 9RS, UK
    Neuroimage 31:489-95. 2006
    ..This technique also offers a novel approach for the exploration of the neurobiological correlates of human personality...
  66. ncbi Emotional decision-making and its dissociable components in schizophrenia and schizoaffective disorder: a behavioural and MRI investigation
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
    Neuropsychologia 46:2002-12. 2008
    ....
  67. ncbi Effects of acute nicotine on brain function in healthy smokers and non-smokers: estimation of inter-individual response heterogeneity
    Ulrich Ettinger
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, DeCrespigny Park, PO89, London SE5 8AF, UK
    Neuroimage 45:549-61. 2009
    ..The comparison of within-session ICCs across drug conditions suggests that the effects of nicotine are subject to inter-individual variability at behavioural and neural levels...
  68. ncbi Rumination and negative symptoms in schizophrenia
    Rozmin Halari
    Department of Psychology, Royal Holloway, University of London, Egham, United Kingdom
    J Nerv Ment Dis 197:703-6. 2009
    ..If the findings are replicated, interventions that reduce rumination and rigid thinking might be helpful to reduce some negative symptoms of psychosis...
  69. ncbi Catechol-O-methyltransferase (COMT) val158met genotype is associated with BOLD response as a function of task characteristic
    Ulrich Ettinger
    King s College London, Centre for Neuroimaging Sciences, Institute of Psychiatry, London, UK
    Neuropsychopharmacology 33:3046-57. 2008
    ....
  70. ncbi Sex effects in prepulse inhibition and facilitation of the acoustic startle response: implications for pharmacological and treatment studies
    Ingrid Aasen
    Department of Psychology, Division of Psychological Medicine, Institute of Psychiatry, London, UK
    J Psychopharmacol 19:39-45. 2005
    ....
  71. ncbi Effects of rivastigmine on sustained attention in schizophrenia: an FMRI study
    Ingrid Aasen
    Department of Psychology, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
    J Clin Psychopharmacol 25:311-7. 2005
    ..Our results showed that rivastigmine treatment increased cerebellar activity and influenced attentional processes...
  72. ncbi Evidence for deficit in tasks of ventral, but not dorsal, prefrontal executive function as an endophenotypic marker for bipolar disorder
    Sophia Frangou
    Section of Neurobiology of Psychosis, Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 58:838-9. 2005
    ..We examined whether deficits in VPFC-related inhibitory processes, but not dorsal prefrontal (DPFC) based executive functions, represent an endophenotypic marker for bipolar disorder I (BDI)...
  73. ncbi Volumetric neural correlates of antisaccade eye movements in first-episode psychosis
    Ulrich Ettinger
    Department of Psychology, McGill University, Stewart Biological Sciences Building, 1205 Dr Penfield Ave, Montreal, Quebec H3A 1B1 Canada
    Am J Psychiatry 161:1918-21. 2004
    ..The authors investigated the structural brain correlates of antisaccade performance...
  74. ncbi Cognitive impairment but preservation of sexual dimorphism in cognitive abilities in chronic schizophrenia
    Rozmin Halari
    Centre for Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, PO 46, De Crespigny Park, London SE5 8AF, UK
    Psychiatry Res 141:129-39. 2006
    ..It is concluded that normal sexual dimorphism is undisturbed on both spatial and verbal tasks by the schizophrenia disease process...
  75. ncbi Relationship between brain structure and saccadic eye movements in healthy humans
    Ulrich Ettinger
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Neurosci Lett 328:225-8. 2002
    ..These findings agree with previous studies on the role of the cerebellar vermis in saccadic gain and support the validity of structural neuroimaging methods in elucidating the neural correlates of saccadic eye movements...
  76. ncbi Abnormal asymmetry of N200 and P300 event-related potentials in subclinical depression
    Alexander Luke Sumich
    Kings College London, Institute of Psychiatry, BIAU, Centre for Neuroimaging Sciences, UK
    J Affect Disord 92:171-83. 2006
    ..Results support involvement of various cognitive mechanisms measured by P300 and N200 in subclinical depressive symptoms some of which may rely on sex...
  77. ncbi Does self-perceived mood predict more variance in cognitive performance than clinician-rated symptoms in schizophrenia?
    Rozmin Halari
    Department of Psychology, Centre for Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, PO 46, De Crespigny Park, London SE5 8AF, UK
    Schizophr Bull 32:751-7. 2006
    ..Self-perceived negative mood state may be a better predictor of cognitive deficits than clinician-rated symptoms in chronic schizophrenia patients...
  78. ncbi Frontal lobe volumes in schizophrenia: effects of stage and duration of illness
    Preethi Premkumar
    King s College London, Institute of Psychiatry, Department of Psychology, PO78, De Crespigny Park, London SE5 8AF, UK
    J Psychiatr Res 40:627-37. 2006
    ..The enlargement of the premotor cortex and putamen are likely to be a result of antipsychotic medication...
  79. ncbi Sex differences and individual differences in cognitive performance and their relationship to endogenous gonadal hormones and gonadotropins
    Rozmin Halari
    Department of Psychology, City University, London, England
    Behav Neurosci 119:104-17. 2005
    ....
  80. ncbi Decomposing the neural correlates of antisaccade eye movements using event-related FMRI
    Ulrich Ettinger
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
    Cereb Cortex 18:1148-59. 2008
    ..These areas likely fulfill a more general supervisory role in the volitional control of eye movements, such as stimulus appraisal, task set, and decision making...
  81. ncbi Reliability of smooth pursuit, fixation, and saccadic eye movements
    Ulrich Ettinger
    Section of Cognitive Psychopharmacology, Division of Psychological Medicine, Institute of Psychiatry, University of London, UK
    Psychophysiology 40:620-8. 2003
    ..These findings support the trait nature of oculomotor function and point to the need to take into consideration between-session practice effects on the antisaccade task in longitudinal studies...
  82. ncbi Event-related potential correlates of depression, insight and negative symptoms in males with recent-onset psychosis
    Alex Sumich
    King s College London, Institute of Psychiatry, BIAU, Biostatistics and Computing, Centre for Neuroimaging Sciences, London SE5 8AF, UK
    Clin Neurophysiol 117:1715-27. 2006
    ..The neurobiology of clinical characteristics -in particular depression, insight and negative symptoms- in recent-onset psychosis (ROP) was studied using event-related potentials (ERPs)...
  83. ncbi A neuropsychological investigation into violence and mental illness
    Ian Barkataki
    Department of Psychological Medicine, Institute of Psychiatry, London, United Kingdom
    Schizophr Res 74:1-13. 2005
    ....
  84. ncbi Structural neural correlates of prosaccade and antisaccade eye movements in healthy humans
    Ulrich Ettinger
    Division of Psychological Medicine, Institute of Psychiatry, London, UK
    Neuroimage 24:487-94. 2005
    ....
  85. ncbi The relationship of structural alterations to cognitive deficits in schizophrenia: a voxel-based morphometry study
    Elena Antonova
    Department of Psychology, Institute of Psychiatry, London, UK
    Biol Psychiatry 58:457-67. 2005
    ..Region of interest studies have identified a number of structure-cognition associations in schizophrenia and revealed alterations in structure-cognition relationship in this population...
  86. ncbi N100 and P300 amplitude to Go and No-Go variants of the auditory oddball in siblings discordant for schizophrenia
    Alex Sumich
    King s College London, Institute of Psychiatry, BIAU, Centre for Neuroimaging Sciences, London SE5 8AF, UK
    Schizophr Res 98:265-77. 2008
    ..P300 amplitude reduction is reliably seen in schizophrenia. Inconsistent reports of isolated frontal and/or parietal deficits in unaffected family members may be clarified using a task that places greater load on frontal function...
  87. ncbi Event-related potential correlates of paranormal ideation and unusual experiences
    Alex Sumich
    BIAU, Biostatistics and Computing, Institute of Psychiatry, King s College London, London, UK
    Cortex 44:1342-52. 2008
    ..The sex differences observed are consistent with those previously observed in individuals with schizophrenia...
  88. ncbi Misattribution bias of threat-related facial expressions is related to a longer duration of illness and poor executive function in schizophrenia and schizoaffective disorder
    Preethi Premkumar
    Department of Psychology, PO78, Institute of Psychiatry, King s College London, De Crespigny, Denmark Hill, London SE5 8AF, United Kingdom
    Eur Psychiatry 23:14-9. 2008
    ....
  89. ncbi Neuropsychological function-brain structure relationships and stage of illness: an investigation into chronic and first-episode schizophrenia
    Preethi Premkumar
    Department of Psychology, Institute of Psychiatry, King s College London, London, UK
    Psychiatry Res 162:195-204. 2008
    ..A similar dissociation between young and older subjects of both healthy and patient groups suggests that a 'bigger-is-better' relationship style is present in older individuals regardless of a diagnosis of schizophrenia...
  90. ncbi The relationship between brain structure and neurocognition in schizophrenia: a selective review
    Elena Antonova
    Division of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Schizophr Res 70:117-45. 2004
    ..Finally, the methodological limitations of the reviewed studies are discussed and suggestions for future research are offered...
  91. ncbi Comparable fMRI activity with differential behavioural performance on mental rotation and overt verbal fluency tasks in healthy men and women
    Rozmin Halari
    Centre for Social, Genetic and Developmental Psychiatry, Institute of Psychiatry, De Crespigny Park, P O Box 46, London SE5 8AF, UK
    Exp Brain Res 169:1-14. 2006
    ..Our results demonstrate comparable brain activation in men and women in association with mental rotation and verbal fluency function with differential performance, and provide support for sex differences in brain-behaviour relationships...
  92. ncbi Disease, deficit or denial? Models of poor insight in psychosis
    M A Cooke
    Department of Psychology, Institute of Psychiatry, London, UK
    Acta Psychiatr Scand 112:4-17. 2005
    ..To examine the evidence for the three kinds of aetiological model that dominate the current literature on poor insight in psychosis: clinical models, the neuropsychological model, and the psychological denial model...
  93. ncbi Focal structural changes and cognitive dysfunction in juvenile myoclonic epilepsy
    J O'Muircheartaigh
    Department of Clinical Neuroscience, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
    Neurology 76:34-40. 2011
    ..The aim of this study was to determine if there were focal cortical abnormalities in juvenile myoclonic epilepsy (JME) using neuropsychological investigations and MRI...
  94. ncbi Neuroimaging of sexual arousal: research and clinical utility
    A L Sumich
    Division of Psychological Medicine, Institute of Psychiatry, London SE5 8AF
    Hosp Med 64:28-33. 2003
    ..Neuroimaging techniques offer insight into brain regions involved in sexual arousal and inhibition. The development of robust paradigms has implications for the assessment and treatment of sexual disorder in men and women...
  95. ncbi Effects of oral procyclidine administration on cognitive functions in healthy subjects: implications for schizophrenia
    Elizabeth Zachariah
    J Clin Psychopharmacol 22:224-6. 2002
  96. ncbi Cognitive effects of olanzapine and clozapine treatment in chronic schizophrenia
    Tonmoy Sharma
    Clinical Neuroscience Research Centre, 7 Twisleton Court, Priory Hill, Dartford, DA1 2EN, Kent, UK
    Psychopharmacology (Berl) 169:398-403. 2003
    ..Typical antipsychotics, although effective in reducing positive symptoms of the illness, have not shown much effect on cognitive functions. Atypical antipsychotics have shown promise of improving some cognitive functions...
  97. ncbi Schizoaffective disorder: diagnostic issues and future recommendations
    Gin S Malhi
    Northern Clinical School, University of Sydney, Sydney, Australia
    Bipolar Disord 10:215-30. 2008
    ..This paper addresses the controversy regarding the diagnostic validity of schizoaffective disorder (SAD), a diagnosis that is used in both DSM-IV and ICD-10 and one that encroaches on both schizophrenia (SCZ) and bipolar disorder (BD)...
  98. ncbi Saccadic eye movements, schizotypy, and the role of neuroticism
    Ulrich Ettinger
    Department of Psychology, McGill University, Stewart Biological Sciences Building, 1205 Dr Penfield Ave, Montreal, Que, Canada H3A 1B1
    Biol Psychol 68:61-78. 2005
    ..We conclude that saccadic performance patterns in schizotypy are not due to negative emotionality or general psychopathology, but specific to schizophrenia spectrum signs and symptoms...
  99. ncbi Cognitive effects of adjunctive 24-weeks Rivastigmine treatment to antipsychotics in schizophrenia: a randomized, placebo-controlled, double-blind investigation
    Tonmoy Sharma
    Clinical Research, Clinical Neuroscience Research Centre, Priory Hill, Dartford, Kent, UK
    Schizophr Res 85:73-83. 2006
    ..Future studies should investigate the effects of other procholinergic drugs, such as Galantamine, which also act on the nicotine receptors and may produce stronger cognitive effects in schizophrenia...
  100. ncbi Disruption of learned irrelevance in acute schizophrenia in a novel continuous within-subject paradigm suitable for fMRI
    Andrew M J Young
    School of Psychology, University of Leicester, University Road, Leicester LE1 7RH, UK
    Behav Brain Res 156:277-88. 2005
    ..These findings establish the likely value of the new paradigm for neuroimaging studies of attentional dysfunction in acute schizophrenia...
  101. ncbi Regional cortical thinning in subjects with violent antisocial personality disorder or schizophrenia
    Veena M Narayan
    Laboratory of Neuro Imaging, Ahmanson Lovelace Brain Mapping Center, Department of Neurology, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    Am J Psychiatry 164:1418-27. 2007
    ....