Research Topics
Genomes and GenesSpecies | Robert KeersSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP projectR Keers
MRC SGDP, Institute of Psychiatry, King s College London, London, UK
Pharmacogenomics J 11:138-45. 2011..Gene-environment interactions including life events may therefore be important not only in the aetiology of depression, but also in predicting response to antidepressant medication...
Gene-environment interaction in major depression and antidepressant treatment responseRobert Keers
MRC SGDP Centre, Institute of Psychiatry at King s College London, 16 De Crespigny Park, Denmark Hill, London, SE5 8AF, England, UK
Curr Psychiatry Rep 14:129-37. 2012..These findings suggest that the dissection of etiological pathways to depression may provide the key to understanding and predicting response to antidepressants...
Stressful life events, cognitive symptoms of depression and response to antidepressants in GENDEPRobert Keers
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Affect Disord 127:337-42. 2010..There is some evidence to suggest that SLEs prior to treatment are associated with greater cognitive symptoms at baseline and may therefore predict changes in these symptoms specifically...
Variation in GNB3 predicts response and adverse reactions to antidepressantsRobert Keers
MRC SGDP Centre, Institute of Psychiatry, King s College London, UK
J Psychopharmacol 25:867-74. 2011..Our results are consistent with previous associations with GNB3 and emphasize the importance of signalling genes in antidepressant response...
Gender differences in antidepressant drug responseRobert Keers
MRC SGDP Centre, Institute of Psychiatry, King s College London, 16 De Crespigny Park, Denmark Hill, London, UK
Int Rev Psychiatry 22:485-500. 2010..Future studies should therefore consider genotypes of the mother, foetus and infant in antidepressant response...
Pharmacogenetics of antidepressant responseRobert Keers
MRC SGDP Centre, Institute of Psychiatry at King s College London, 16 De Crespigny Park, Denmark Hill, London, SE5 8AF, UK
Expert Rev Neurother 11:101-25. 2011....
Changes in body weight during pharmacological treatment of depressionRudolf Uher
Institute of Psychiatry, King s College London, London, UK
Int J Neuropsychopharmacol 14:367-75. 2011..While treatment with nortriptyline may be recommended in underweight subjects with typical neurovegetative symptoms, escitalopram is a suitable alternative for subjects at risk of weight gain...
Stressful life events and the serotonin transporter gene (5-HTT) in recurrent clinical depressionHelen L Fisher
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, UK
J Affect Disord 136:189-93. 2012....
Stressful life events and the brain-derived neurotrophic factor gene in bipolar disorderGeorgina M Hosang
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, UK
J Affect Disord 125:345-9. 2010..The aim of the present study was to examine the interplay between the BDNF Val(66)Met polymorphism and stressful life events (SLEs) in bipolar disorder...
