Research Topics
| Dominic H ffytcheSummaryAffiliation: King's College London Country: UK Publications
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Detail Information
Publications
Visual hallucinatory syndromes: past, present, and futureDominic H ffytche
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
Dialogues Clin Neurosci 9:173-89. 2007..From a neurobiological perspective, three syndromes emerge that relate to specific dysfunctions of afferent, cholinergic and serotonergic visual circuitry and promise future therapeutic advances...- Beyond localization: from hodology to functionDominic H ffytche
Institute of Psychiatry, PO Box 89, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
Philos Trans R Soc Lond B Biol Sci 360:767-79. 2005.... - Visual command hallucinations in a patient with pure alexiaD H Ffytche
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5, UK
J Neurol Neurosurg Psychiatry 75:80-6. 2004..Syntacto-semantic visual hallucinations may represent a separate category of textual hallucinations related to the cortical network implicated in the auditory hallucinations of schizophrenia... - Are neural correlates of visual consciousness retinotopic?Dominic H ffytche
Institute of Psychiatry PO 70, De Crespigny Park, London SE5 8AF, UK
Neuroreport 14:2011-4. 2003..Our results point to a retinotopic organisation of perceptual activity in early visual areas, with independent perceptual activations for different regions of visual space... - Disorders of visual perceptionDominic H ffytche
Department of Old Age Psychiatry, Institute of Psychiatry PO70, King s College London, De Crespigny Park, London SE5 8AF, UK
J Neurol Neurosurg Psychiatry 81:1280-7. 2010..The wider perspective forces us to consider what visual functions underlie a range of symptoms sidelined by previous classificatory schemes and helps generate novel hypotheses for further research in the area... - The hodology of hallucinationsDominic H ffytche
Centre for Neuroimaging Sciences, Institute of Psychiatry, De Crespigny Park, London, UK
Cortex 44:1067-83. 2008..The third part of the paper considers the relevance of the finding to other disorders, examines the strengths and limitations of our current imaging approaches to connectivity and looks to future developments in the field... - Visual hallucinations in eye diseaseDominic H ffytche
Section of Old Age Psychiatry and Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, UK
Curr Opin Neurol 22:28-35. 2009..The literature related to visual hallucinations in ophthalmological settings from 2007 to 2008 is presented as a review of recent developments and trends... - Visual hallucinatory syndromes and the anatomy of the visual brainA M Santhouse
Institute of Psychiatry, London, UK
Brain 123:2055-64. 2000..The three visual psycho-syndromes mirror the segregation of hierarchical visual pathways into streams and suggest a novel theoretical framework for future research into the pathophysiology of neuropsychiatric syndromes... - The perceptual consequences of visual loss: 'positive' pathologies of visionD H Ffytche
Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
Brain 122:1247-60. 1999..The known neurophysiology of the visual cortex helps explain the phenomenology of the experiences and provides the basis for a neurobiologically based classification of positive and negative visual perceptual disorders... - Visual hallucinations and the Charles Bonnet syndromeDominic H ffytche
Centre for Neuroimaging Sciences, Institute of Psychiatry, PO 89 De Crespigny Park, Denmark Hill, London SE5 8AF, United Kingdom
Curr Psychiatry Rep 7:168-79. 2005..The implication is of two independent but interacting pathophysiologic mechanisms and of a need to reassess the classification and management of this common psychopathologic symptom... - Functional MRI of verbal self-monitoring in schizophrenia: performance and illness-specific effectsVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Schizophr Bull 36:740-55. 2010..Altered striatal and hypothalamic modulation to own and others' voice characterizes emotionally withdrawn and socially avoidant patients... - Neural and behavioural responses to threat in men with a history of serious violence and schizophrenia or antisocial personality disorderVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Schizophr Res 110:47-58. 2009..This study examined behavioural and brain abnormalities in violent men with schizophrenia or APD during anticipatory fear... - The rises and falls of disconnection syndromesMarco Catani
Centre for Neuroimaging Sciences, Institute of Psychiatry, De Crespigny Park, London, UK
Brain 128:2224-39. 2005.... - Neural changes following cognitive behaviour therapy for psychosis: a longitudinal studyVeena Kumari
Department of Psychology, King s College London, London SE5 8AF, UK
Brain 134:2396-407. 2011.... - Visual processing, social cognition and functional outcome in schizophreniaPhilip Brittain
Affective Neuroscience Group, Section of Cognitive Neuropsychiatry, King s College London, Institute of Psychiatry, 16 De Crespigny Park, London SE5 8AF, UK
Psychiatry Res 178:270-5. 2010..In conclusion, the pathophysiology of visual dysfunction affects low- and high-level visual areas similarly and the relationship between deficits and outcome is small and indirect... - Perisylvian language networks of the human brainMarco Catani
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, DeCrespigny Park, London SE5 8AZ, United Kingdom
Ann Neurol 57:8-16. 2005..The anatomical findings are also relevant to the evolution of language, provide a framework for Lichtheim's symptom-based neurological model of aphasia, and constrain, anatomically, contemporary connectionist accounts of language... - Neuroticism and brain responses to anticipatory fearVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London, De Crespigny Park, London, United Kingdom
Behav Neurosci 121:643-52. 2007..The observations support recent psychophysiological research that has demonstrated reduced processing of pain in subjects with higher levels of neuroticism, especially the anxiety component of this trait... - Decomposing the neural correlates of antisaccade eye movements using event-related FMRIUlrich Ettinger
Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, UK
Cereb Cortex 18:1148-59. 2008..These areas likely fulfill a more general supervisory role in the volitional control of eye movements, such as stimulus appraisal, task set, and decision making... - Differences between Alzheimer's disease and dementia with Lewy bodies: an fMRI study of task-related brain activityJustin Sauer
King s College London, MRC Centre for Neurodegeneration Research, Section of Old Age Psychiatry, Institute of Psychiatry London, UK
Brain 129:1780-8. 2006.... - Atlasing location, asymmetry and inter-subject variability of white matter tracts in the human brain with MR diffusion tractographyMichel Thiebaut de Schotten
Natbrainlab, Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, London, UK
Neuroimage 54:49-59. 2011..This study suggests that DTI-derived maps can be used together with a previous histological atlas to establish the relationship of focal lesions with nearby tracts and improve clinico-anatomical correlation... - Personality predicts brain responses to cognitive demandsVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF, United Kingdom
J Neurosci 24:10636-41. 2004..These observations suggest that individual differences affect brain responses during cognitive activity and at rest and provide evidence for the hypothesized neurobiological basis of personality... - Cognitive effects of nicotine in humans: an fMRI studyVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College, London, UK
Neuroimage 19:1002-13. 2003.... - Self-responsibility and the self-serving bias: an fMRI investigation of causal attributionsN J Blackwood
Division of Psychological Medicine, Institute of Psychiatry, London, UK
Neuroimage 20:1076-85. 2003..The dorsal striatum, previously implicated in motivated behavior, mediates the self-serving bias... - Persecutory delusions and the determination of self-relevance: an fMRI investigationN J Blackwood
Department of Psychological Medicine, Institute of Psychiatry, London
Psychol Med 34:591-6. 2004..This study aimed to characterize these social cognitive biases in functional neuroanatomical terms... - fMRI BOLD response to increasing task difficulty during successful paired associates learningR L Gould
Section of Old Age Psychiatry, Institute of Psychiatry, King s College, London, UK
Neuroimage 20:1006-19. 2003..The cortical response to increasing cognitive demands or TD appears to involve the same, rather than an additional, network of brain regions "working harder.".. - Backward and forward visual masking in schizophrenia and its relation to global motion and global form perceptionP J Brittain
Affective Neuroscience Group, Section of Cognitive Neuropsychiatry, King s College London, Institute of Psychiatry, 16 De Crespigny Park, London SE5 8AF, UK
Schizophr Res 124:134-41. 2010..The results suggest an 'early visual' processing deficit in both magno- and parvocellular systems but one which is only transferred to 'down-stream' processing areas with predominantly magnocellular input... - Functional imaging of the mechanisms underlying the bilateral field advantageA M Santhouse
Institute of Psychiatry, De Crespigny Park, London SE5 8AF, United Kingdom
Neuroimage 17:680-7. 2002..The results suggest different processing strategies with different temporal characteristics in the bilateral and unilateral conditions, providing a novel explanation for the bilateral field advantage... - The functional significance of perinatal corpus callosum damage: an fMRI study in young adultsA M Santhouse
Institute of Psychiatry, King s College, De Crespigny Park, London, UK
Brain 125:1782-92. 2002..On the auditory task, a deficit of activity was seen in the right temporal lobe of the callosum group. The findings reveal a plasticity of function compensating for early damage to the corpus callosum... - Occipito-temporal connections in the human brainMarco Catani
Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Brain 126:2093-107. 2003..Future tractography studies of patients with occipito-temporal disconnection syndromes may help define the functional roles of the direct and indirect occipito-temporal pathways... - Evidence against functionalism from neuroimaging of the alien colour effect in synaesthesiaJeffrey A Gray
Centre for Neuroimaging Sciences, Institute of Psychiatry, King's College London, De Crespigny Park, London, UK
Cortex 42:309-18. 2006..Whatever its merits as an account of other mental states, reductive functionalism cannot be the correct account of conscious experiences... - Disruption of frontal ? coherence by ?9-tetrahydrocannabinol is associated with positive psychotic symptomsPaul D Morrison
The Biomedical Research Centre, Institute of Psychiatry, King s College London, Denmark Hill, UK
Neuropsychopharmacology 36:827-36. 2011..The results reveal that the pro-psychotic effects of THC might be related to impaired network dynamics with impaired communication between the right and left frontal lobes... - Beyond dopamine: functional MRI predictors of responsiveness to cognitive behaviour therapy for psychosisVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London London, UK
Front Behav Neurosci 4:4. 2010..The findings implicate language processing (IFG), attention (thalamus), insight and self-awareness (medial prefrontal and parietal cortices) in CBTp responsiveness in schizophrenia... - Neural dysfunction and violence in schizophrenia: an fMRI investigationVeena Kumari
Department of Psychology, Institute of Psychiatry, King s College London, London, UK
Schizophr Res 84:144-64. 2006..It is concluded that reduced functional response in the frontal and inferior parietal regions leads to serious violence in schizophrenia perhaps via impaired executive functioning... - The anatomy of conscious vision: an fMRI study of visual hallucinationsD H Ffytche
Institute of Psychiatry, London, UK
Nat Neurosci 1:738-42. 1998.... - PYY modulation of cortical and hypothalamic brain areas predicts feeding behaviour in humansRachel L Batterham
Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK
Nature 450:106-9. 2007..An increased understanding of how such homeostatic and higher brain functions are integrated may pave the way for the development of new treatment strategies for obesity...