Christine Ecker

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study
    Christine Ecker
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, De Crespigny Park, London, England
    Arch Gen Psychiatry 69:195-209. 2012
  2. ncbi Describing the brain in autism in five dimensions--magnetic resonance imaging-assisted diagnosis of autism spectrum disorder using a multiparameter classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, Brain Image Analysis Unit, Centre for Neuroimaging Sciences, King s College, London SE5 8AF, United Kingdom
    J Neurosci 30:10612-23. 2010
  3. ncbi Combining path analysis with time-resolved functional magnetic resonance imaging: the neurocognitive network underlying mental rotation
    Christine Ecker
    Brain Image Analysis Unit, Centre for Neuroimaging Sciences, Institute of Psychiatry, London, UK
    J Cogn Neurosci 20:1003-20. 2008
  4. ncbi Investigating the predictive value of whole-brain structural MR scans in autism: a pattern classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuroimage 49:44-56. 2010
  5. ncbi Effects of acute tryptophan depletion on neural processing of facial expressions of emotion in humans
    Eileen Daly
    Section of Brain Maturation, Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Psychopharmacology (Berl) 210:499-510. 2010
  6. ncbi Reduced activation and inter-regional functional connectivity of fronto-striatal networks in adults with childhood Attention-Deficit Hyperactivity Disorder (ADHD) and persisting symptoms during tasks of motor inhibition and cognitive switching
    Ana Cubillo
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London SE5 8AF, UK
    J Psychiatr Res 44:629-39. 2010
  7. ncbi Fronto-striatal circuitry and inhibitory control in autism: findings from diffusion tensor imaging tractography
    Marieke Langen
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK
    Cortex 48:183-93. 2012
  8. ncbi Detecting functional nodes in large-scale cortical networks with functional magnetic resonance imaging: a principal component analysis of the human visual system
    Christine Ecker
    Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, London, United Kingdom
    Hum Brain Mapp 28:817-34. 2007
  9. ncbi Autism in adults. New biologicial findings and their translational implications to the cost of clinical services
    Declan G M Murphy
    Department of Forensic and Developmental Sciences, Institute of Psychiatry, Kings College London, London, UK
    Brain Res 1380:22-33. 2011
  10. ncbi Is there a common underlying mechanism for age-related decline in cortical thickness?
    Christine Ecker
    Section of Brain Maturation, PO50, Institute of Psychiatry, De Crespigny Park, London SE58AF, UK
    Neuroreport 20:1155-60. 2009

Detail Information

Publications14

  1. ncbi Brain anatomy and its relationship to behavior in adults with autism spectrum disorder: a multicenter magnetic resonance imaging study
    Christine Ecker
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, De Crespigny Park, London, England
    Arch Gen Psychiatry 69:195-209. 2012
    ..There is consensus that autism spectrum disorder (ASD) is accompanied by differences in neuroanatomy. However, the neural substrates of ASD during adulthood, as well as how these relate to behavioral variation, remain poorly understood...
  2. ncbi Describing the brain in autism in five dimensions--magnetic resonance imaging-assisted diagnosis of autism spectrum disorder using a multiparameter classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, Brain Image Analysis Unit, Centre for Neuroimaging Sciences, King s College, London SE5 8AF, United Kingdom
    J Neurosci 30:10612-23. 2010
    ..The spatial patterns detected using SVM may help further exploration of the specific genetic and neuropathological underpinnings of ASD, and provide new insights into the most likely multifactorial etiology of the condition...
  3. ncbi Combining path analysis with time-resolved functional magnetic resonance imaging: the neurocognitive network underlying mental rotation
    Christine Ecker
    Brain Image Analysis Unit, Centre for Neuroimaging Sciences, Institute of Psychiatry, London, UK
    J Cogn Neurosci 20:1003-20. 2008
    ..The results of path analysis in fMRI should therefore only be interpreted in the light of a specific experimental design and should not be considered as general indicators of effective connections...
  4. ncbi Investigating the predictive value of whole-brain structural MR scans in autism: a pattern classification approach
    Christine Ecker
    Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, King s College, London, UK
    Neuroimage 49:44-56. 2010
    ..Also, these differences provide significant predictive power for group membership, which is related to symptom severity...
  5. ncbi Effects of acute tryptophan depletion on neural processing of facial expressions of emotion in humans
    Eileen Daly
    Section of Brain Maturation, Department of Psychological Medicine and Psychiatry, Institute of Psychiatry, King s College London, London, UK
    Psychopharmacology (Berl) 210:499-510. 2010
    ..Acute tryptophan depletion (ATD) temporarily lowers brain serotonin (5-HT) synthesis, and behavioral studies have shown that this alters the processing of facial expressions of emotion...
  6. ncbi Reduced activation and inter-regional functional connectivity of fronto-striatal networks in adults with childhood Attention-Deficit Hyperactivity Disorder (ADHD) and persisting symptoms during tasks of motor inhibition and cognitive switching
    Ana Cubillo
    Department of Child Psychiatry, Institute of Psychiatry, King s College, London SE5 8AF, UK
    J Psychiatr Res 44:629-39. 2010
    ..This suggests that neuro-functional abnormalities in ADHD patients are likely to continue between childhood and early adulthood...
  7. ncbi Fronto-striatal circuitry and inhibitory control in autism: findings from diffusion tensor imaging tractography
    Marieke Langen
    Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, King s College London, UK
    Cortex 48:183-93. 2012
    ..There are few studies, however, that have measured the micro-structural organisation of white matter tracts connecting striatum and frontal cortex...
  8. ncbi Detecting functional nodes in large-scale cortical networks with functional magnetic resonance imaging: a principal component analysis of the human visual system
    Christine Ecker
    Brain Image Analysis Unit, Department of Biostatistics and Computing, Institute of Psychiatry, London, United Kingdom
    Hum Brain Mapp 28:817-34. 2007
    ....
  9. ncbi Autism in adults. New biologicial findings and their translational implications to the cost of clinical services
    Declan G M Murphy
    Department of Forensic and Developmental Sciences, Institute of Psychiatry, Kings College London, London, UK
    Brain Res 1380:22-33. 2011
    ....
  10. ncbi Is there a common underlying mechanism for age-related decline in cortical thickness?
    Christine Ecker
    Section of Brain Maturation, PO50, Institute of Psychiatry, De Crespigny Park, London SE58AF, UK
    Neuroreport 20:1155-60. 2009
    ..This model reconciles two seemingly mutually exclusive hypotheses, namely, the existence of different decay functions being caused by the same underlying mechanism...
  11. ncbi The development of emotion-processing in children: effects of age, emotion, and intensity
    Catherine M Herba
    Department of Psychological Medicine, Institute of Psychiatry, KCL, UK
    J Child Psychol Psychiatry 47:1098-106. 2006
    ..This study examined the effects of age and two novel factors (intensity and emotion category) on healthy children's developing emotion-processing from 4 to 15 years using two matching paradigms...
  12. ncbi Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression
    Natalia S Lawrence
    Section of Neuroscience and Emotion, Institute of Psychiatry, London, United Kingdom
    Biol Psychiatry 55:578-87. 2004
    ..CONCLUSIONS: Compared with healthy controls and MDD patients, BD patients demonstrated increased subcortical and ventral prefrontal cortical responses to both positive and negative emotional expressions...
  13. ncbi Time-resolved fMRI of mental rotation revisited--dissociating visual perception from mental rotation in female subjects
    Christine Ecker
    Brain Image Analysis Unit, PO Box 89, Centre for Neuroimaging Sciences CNS, Institute of Psychiatry, King s College London, DeCrespigny Park, London, SE5 8AF, UK
    Neuroimage 32:432-44. 2006
    ....
  14. ncbi Human attachment security is mediated by the amygdala: evidence from combined fMRI and psychophysiological measures
    Erwin Lemche
    Division of Psychological Medicine, Section of Neuroscience and Emotion, Institute of Psychiatry, London, United Kingdom
    Hum Brain Mapp 27:623-35. 2006
    ..We thereby demonstrate a key role of the amygdala in mediating autonomic activity associated with human attachment insecurity...