Research Topics | Malcolm KohlerSummaryAffiliation: John Radcliffe Hospital Country: UK Publications
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Diagnosis, treatment and long-term outcome of solitary fibrous tumours of the pleuraMalcolm Kohler
Division of Pulmonary Medicine, University Hospital of Zurich, Switzerland
Eur J Cardiothorac Surg 32:403-8. 2007..The aim of this study is to present new cases, and discuss up-to-date preoperative examinations, the role of video-assisted thoracic surgery and long-term outcome...- The role of the nose in the pathogenesis of obstructive sleep apnoea and snoringM Kohler
Oxford Centre for Respiratory Medicine, Oxford OX3 7LJ, UK
Eur Respir J 30:1208-15. 2007..The impact of treating nasal obstruction in patients with snoring and obstructive sleep apnoea on long-term outcome remains to be defined through randomised controlled trials of medical and surgical therapies... - Continuous positive airway pressure treatment for obstructive sleep apnoea reduces resting heart rate but does not affect dysrhythmias: a randomised controlled trialSonya Craig
Oxford Centre for Respiratory Medicine, Churchill Hospital, Headington, Oxford OX3 7LJ, United Kingdom
J Sleep Res 18:329-36. 2009..Four weeks of CPAP therapy reduces mean 24-h heart rate possibly due to reduced sympathetic activation but did not result in a significant decrease in dysrhythmia frequency... - Obstructive sleep apnea in patients with abdominal aortic aneurysms: highly prevalent and associated with aneurysm expansionRebecca H Mason
Oxford Centre for Respiratory Medicine, Churchill Hospital, United Kingdom
Am J Respir Crit Care Med 183:668-74. 2011..Abdominal aortic aneurysms (AAA) are associated with life-threatening complications. The likelihood that an AAA will rupture is influenced by the aneurysm diameter and its expansion rate; reasons for rapid expansion are largely unknown... - The effect of continuous positive airway pressure treatment on physical activity in patients with obstructive sleep apnoea: A randomised controlled trialSophie D West
Oxford Centre for Respiratory Medicine, Churchill Hospital, Headington, UK
Sleep Med 10:1056-8. 2009..Continuous positive airway pressure (CPAP) improves daytime sleepiness in patients with obstructive sleep apnoea (OSA). The effect of CPAP on physical activity is unclear. We hypothesized that activity would increase after CPAP treatment... - Predictors of long-term compliance with continuous positive airway pressureMalcolm Kohler
Sleep Disorders Centre and Pulmonary Division, University Hospital of Zurich, Raemistrasse 100, 8091 Zurich, Switzerland
Thorax 65:829-32. 2010..There are very few data on objectively assessed long-term compliance with continuous positive airway pressure (CPAP). No single factor has been consistently identified as predictive of continued CPAP use... - Endothelial function and arterial stiffness in minimally symptomatic obstructive sleep apneaMalcolm Kohler
Oxford Centre for Respiratory Medicine, Churchill Hospital, Headington, Oxford OX3 7LJ, UK
Am J Respir Crit Care Med 178:984-8. 2008..Moderate-severe obstructive sleep apnea (OSA) is associated with endothelial dysfunction, increased arterial stiffness, and hypertension. It is not known whether minimally symptomatic OSA is also associated with impaired vascular function... - The role of the nose in the pathogenesis of obstructive sleep apneaMalcolm Kohler
Pulmonary Division, University Hospital of Zurich, Zurich, Switzerland
Curr Opin Otolaryngol Head Neck Surg 17:33-7. 2009.... - Pharmacological approaches to the treatment of obstructive sleep apnoeaMalcolm Kohler
University Hospital of Zurich, Sleep Disorders Centre and Pulmonary Division, Raemistrasse 100, Zurich 8091, Switzerland
Expert Opin Investig Drugs 18:647-56. 2009..Some patients with OSA do not tolerate CPAP or have insufficiently severe symptoms to justify its use; for these patients, drug therapy would be a desirable potential therapeutic alternative...