R T Cullen

Summary

Affiliation: Institute of Occupational Medicine
Country: UK

Publications

  1. ncbi Pulmonary and intraperitoneal inflammation induced by cellulose fibres
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    J Appl Toxicol 20:49-60. 2000
  2. ncbi Pathogenicity of a special-purpose glass microfiber (E glass) relative to another glass microfiber and amosite asbestos
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    Inhal Toxicol 12:959-77. 2000
  3. ncbi Inhalation of poorly soluble particles. I. Differences in inflammatory response and clearance during exposure
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, United Kingdom
    Inhal Toxicol 12:1089-111. 2000
  4. ncbi Tumorigenicity of cellulose fibers injected into the rat peritoneal cavity
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    Inhal Toxicol 14:685-703. 2002
  5. ncbi Influence of fibre length, dissolution and biopersistence on the production of mesothelioma in the rat peritoneal cavity
    B G Miller
    Institute of Occupational Medicine, Edinburgh, UK
    Ann Occup Hyg 43:155-66. 1999
  6. ncbi Inhalation of poorly soluble particles. II. Influence Of particle surface area on inflammation and clearance
    C L Tran
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    Inhal Toxicol 12:1113-26. 2000
  7. ncbi Short-term inhalation and in vitro tests as predictors of fiber pathogenicity
    R T Cullen
    Institute of Occupational Medicine, Edinburgh, United Kingdom
    Environ Health Perspect 105:1235-40. 1997
  8. ncbi Biopersistence and durability of nine mineral fibre types in rat lungs over 12 months
    A Searl
    Institute of Occupational Medicine, Edinburgh, UK
    Ann Occup Hyg 43:143-53. 1999

Collaborators

Detail Information

Publications8

  1. ncbi Pulmonary and intraperitoneal inflammation induced by cellulose fibres
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    J Appl Toxicol 20:49-60. 2000
    ..We conclude that the cellulose material studied is less inflammogenic than crocidolite and that the extent of the inflammatory response within the lung appears to reduce with continued exposure over a 14-day period...
  2. ncbi Pathogenicity of a special-purpose glass microfiber (E glass) relative to another glass microfiber and amosite asbestos
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    Inhal Toxicol 12:959-77. 2000
    ....
  3. ncbi Inhalation of poorly soluble particles. I. Differences in inflammatory response and clearance during exposure
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, United Kingdom
    Inhal Toxicol 12:1089-111. 2000
    ..The explanation that the different responses are due to the different particle size distributions of the two dust types is examined in a companion paper (Tran et al., this issue)...
  4. ncbi Tumorigenicity of cellulose fibers injected into the rat peritoneal cavity
    R T Cullen
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    Inhal Toxicol 14:685-703. 2002
    ..This study has demonstrated that a high dose of cellulose fibers is capable of producing tumors when injected into the abdominal cavity of rats...
  5. ncbi Influence of fibre length, dissolution and biopersistence on the production of mesothelioma in the rat peritoneal cavity
    B G Miller
    Institute of Occupational Medicine, Edinburgh, UK
    Ann Occup Hyg 43:155-66. 1999
    ..Improved quantification of the relative importance of fibre dimensions and biopersistence indices requires experimentation with a range of doses...
  6. ncbi Inhalation of poorly soluble particles. II. Influence Of particle surface area on inflammation and clearance
    C L Tran
    Institute of Occupational Medicine, 8 Roxburgh Place, Edinburgh EH8 9SU, UK
    Inhal Toxicol 12:1113-26. 2000
    ..On the basis of this and other similar results, a hypothesis regarding a generic mechanism for the impairment of clearance and associated lung responses is proposed for such "low-toxicity" dusts...
  7. ncbi Short-term inhalation and in vitro tests as predictors of fiber pathogenicity
    R T Cullen
    Institute of Occupational Medicine, Edinburgh, United Kingdom
    Environ Health Perspect 105:1235-40. 1997
    ..We believe that this assay should be validated with a wider range of fibers, doses, and time points...
  8. ncbi Biopersistence and durability of nine mineral fibre types in rat lungs over 12 months
    A Searl
    Institute of Occupational Medicine, Edinburgh, UK
    Ann Occup Hyg 43:143-53. 1999
    ..Biopersistence was influenced by both fibre dimensions and solubility...