Research Topics
| Gilbert R ThompsonSummaryAffiliation: Imperial College Country: UK Publications
| Collaborators
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Detail Information
Publications
Novel lipid-regulating drugsG R Thompson
Division of Investigative Science, Imperial College School of Medicine and MRC Molecular Medicine Group, MRC Clinical Sciences Centre, Hammersmith Hospital, London, UK
Expert Opin Investig Drugs 9:2619-28. 2000....- Coronary calcification score: the coronary-risk impact factorG R Thompson
Metabolic Medicine, Division of Investigative Science, Faculty of Medicine, Imperial College, Hammersmith Hospital, London W12 ONN, UK
Lancet 363:557-9. 2004..It would also be worth investigating the relation between coronary calcification and risk factors not quantified in Framingham-based estimates, including familial and racial predisposition to premature coronary heart disease... - LDL apheresisGilbert R Thompson
Metabolic Medicine, Division of Investigative Sciences, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, United Kingdom
Atherosclerosis 167:1-13. 2003.... - Screening relatives of patients with premature coronary heart diseaseGilbert R Thompson
Metabolic Medicine, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
Heart 87:390-4. 2002 - Why some patients respond poorly to statins and how this might be remediedG R Thompson
Department of Investigative Science, Imperial College School of Medicine, Hammersmith Hospital, London, UK
Eur Heart J 23:200-6. 2002 - Goals of statin therapy: three viewpointsGilbert R Thompson
Metabolic Medicine, Imperial College School of Medicine, Hammersmith Hospital, Du Cane Road, London W12 0NN, United Kingdom
Curr Atheroscler Rep 4:26-33. 2002..We asked three investigators, Drs. Gilbert Thompson, Christopher Packard, and Neil Stone, who have all been integrally involved in the accumulation of our present database, to argue three different possible answers... - Management of dyslipidaemiaGilbert R Thompson
Metabolic Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK
Heart 90:949-55. 2004 - Additive effects of plant sterol and stanol esters to statin therapyGilbert R Thompson
Department of Metabolic Medicine, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
Am J Cardiol 96:37D-39D. 2005..They differ in that plasma plant sterols increase when plant sterol esters are used for this purpose, especially in patients with familial hypercholesterolemia, but decrease when plant stanol esters are used... - Comparison of efficacy of plant stanol ester and sterol ester: short-term and longer-term studiesTom A B Sanders
Department of Metabolic Medicine, Division of Investigative Science, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
Am J Cardiol 96:29D-36D. 2005..We conclude that plant stanol esters are preferable for the long-term management of hypercholesterolemia... - Efficacy criteria and cholesterol targets for LDL apheresisGilbert R Thompson
Imperial College, Hammersmith Hospital, London W12 0NN, United Kingdom
Atherosclerosis 208:317-21. 2010..Establishing a uniform approach to data collection would facilitate the setting up of national or multi-national registers and might eventually provide the information needed to formulate evidence-based guidelines for LDL apheresis... - Current management of severe homozygous hypercholesterolaemiasRossi P Naoumova
Medical Research Council Clinical Sciences Centre Imperial College, Hammersmith Hospital, London, UK
Curr Opin Lipidol 15:413-22. 2004..This review focuses on recent advances in the management of patients with homozygous familial hypercholesterolaemia, autosomal recessive hypercholesterolaemia and familial defective apolipoprotein B... - Coronary calcification and predicted risk of coronary heart disease in asymptomatic men with hypercholesterolaemiaRobert S Elkeles
Department of Medicine, St Mary's, London, UK
J Cardiovasc Risk 9:349-53. 2002..However, uncertainties about the predictive power of coronary calcification for coronary events must be resolved before electron beam computed tomography can be used to select high-risk patients for primary prevention... - Severe hypercholesterolaemia: therapeutic goals and eligibility criteria for LDL apheresis in EuropeGilbert R Thompson
Imperial College, Hammersmith Hospital, London, UK
Curr Opin Lipidol 21:492-8. 2010..On the basis of clinical experience, these patients tend to have the most severe forms of familial hypercholesterolaemia or markedly elevated LDL cholesterol (LDL-C) levels but are unable to tolerate statin therapy... - Measurement of the reflectivity of the intima-medial layer of the common carotid artery improves the discriminatory value of intima-medial thickness measurement as a predictor of risk of atherosclerotic diseaseStephen M Ellis
Department of Radiology, King s College Hospital, Denmark Hill, London, UK
Ultrasound Med Biol 33:1029-38. 2007.... - Lipoprotein apheresisGilbert R Thompson
Metabolic Medicine, Imperial College, Hammersmith Hospital, London, UK
Curr Opin Lipidol 21:487-91. 2010..Lipoprotein apheresis is being performed with increasing frequency, but better data collection and recording of clinical outcomes are needed. Setting up registries would facilitate this process... - History and development of plant sterol and stanol esters for cholesterol-lowering purposesGilbert R Thompson
Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
Am J Cardiol 96:3D-9D. 2005..The clinical significance of these changes remains to be determined... - New developments in pharmacotherapyGilbert R Thompson
Cardiovasc J S Afr 15:56-8. 2004 - Is good cholesterol always good?Gilbert R Thompson
BMJ 329:471-2. 2004 - Plasma markers of cholesterol homeostasis and apolipoprotein B-100 kinetics in the metabolic syndromeDick C Chan
School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia
Obes Res 11:591-6. 2003..These changes in cholesterol homeostasis may contribute to the kinetic defects in apoB metabolism in the metabolic syndrome... - Relationships between cholesterol homoeostasis and triacylglycerol-rich lipoprotein remnant metabolism in the metabolic syndromeDick C Chan
University Department of Medicine, University of Western Australia, Western Australian Institute for Medical Research, Royal Perth Hospital, GPO Box X2213, Perth, WA 6847, Australia
Clin Sci (Lond) 104:383-8. 2003..Our findings suggest that in subjects with the MS alterations in cholesterol absorption and synthesis may be closely linked with the kinetic defects in TRL metabolism...