Research Topics
| M E HodsonSummaryAffiliation: Imperial College Country: UK Publications
| Collaborators
|
Detail Information
Publications
Dornase alfa in the treatment of cystic fibrosis in Europe: a report from the Epidemiologic Registry of Cystic FibrosisM E Hodson
Cystic Fibrosis Department, Royal Brompton National Heart and Lung Hospital, London, UK
Pediatr Pulmonol 36:427-32. 2003..The analysis suggested that younger patients were likely to benefit more from treatment. The findings of randomized clinical trials were supported by the data collected in routine clinical practice...
A randomised clinical trial of nebulised tobramycin or colistin in cystic fibrosisM E Hodson
Royal Brompton and Harefield NHS Trust, London, UK
Eur Respir J 20:658-64. 2002..Both treatments reduced the bacterial load...
New clinical evidence from the European tobramycin trial in cystic fibrosisM E Hodson
Department of Cystic Fibrosis, The Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK
J Cyst Fibros 1:199-202. 2002..008). The safety profile of both treatments was good. We conclude that patients treated with TNS for 1 month experience improved lung function compared with patients treated with colistin...
Treatment of cystic fibrosis in the adultM E Hodson
Department of Cystic Fibrosis, Royal Brompton and Harefield NHS Trust, London, UK
Respiration 67:595-607. 2000..Arranging a balanced and reliable system of care - out-patient, in-patient and home care - is essential to ensure the patient's survival and quality of life is as good as possible...
Cystic fibrosis and survival to 40 years: a case-control studyN J Simmonds
Dept of Cystic Fibrosis, Royal Brompton Hospital, Sydney Street, London, UK
Eur Respir J 36:1277-83. 2010..Even "early-diagnosis" disease appears to have different phenotypes, possibly independent of CF gene function, that have different survival patterns...
Beyond postural drainage and percussion: Airway clearance in people with cystic fibrosisJ A Pryor
Department of Cystic Fibrosis, Royal Brompton and Harefield NHS Foundation Trust, London SW3 6NP, UK
J Cyst Fibros 9:187-92. 2010....
Improved survival at low lung function in cystic fibrosis: cohort study from 1990 to 2007P M George
Department of Cystic Fibrosis, Royal Brompton Hospital, London SW3 6NP, UK
BMJ 342:d1008. 2011..Design Cohort study...
Cystic fibrosis and survival to 40 years: a study of cystic fibrosis transmembrane conductance regulator functionN J Simmonds
Dept of Cystic Fibrosis, Royal Brompton Hospital, London, SW3 6NP, UK
Eur Respir J 37:1076-82. 2011..5 (80.0-113.5) mmol·L?¹; young/mild). ? Amil is associated with FEV? but our findings indicate that long-term survival cannot be explained by residual CFTR function when measurements are taken in later life...
Relationship of skeletal muscle mass, muscle strength and bone mineral density in adults with cystic fibrosisS L Elkin
Department of Cystic Fibrosis at the Royal Brompton Hospital, Imperial College School of Medicine, Sydney Street, London SW3 6NP, UK
Clin Sci (Lond) 99:309-14. 2000..BMD is also reduced in CF subjects, and this appears to be related to shorter stature in this group...
A case-controlled study with dornase alfa to evaluate impact on disease progression over a 4-year periodP L Shah
Department of Cystic Fibrosis, Royal Brompton Hospital and National Heart and Lung Institute, Imperial College, London, UK
Respiration 68:160-4. 2001..034). CONCLUSIONS: The trends suggest that dornase alfa may have some influence on disease progression but in view of the limitations of the current study the need for further long-term studies in larger cohorts of patients is emphasised...
Vertebral deformities and low bone mineral density in adults with cystic fibrosis: a cross-sectional studyS L Elkin
Department of Cystic Fibrosis, National Heart and Lung Institute, Royal Brompton Hospital, London
Osteoporos Int 12:366-72. 2001..Low BMD occurs in patients with more severe disease and significantly relates to FEV1, infective exacerbations and daily energy expended in physical activity...
The psychosocial and psychiatric side of cystic fibrosis in adolescents and adultsP E Pfeffer
Department of Cystic Fibrosis, Royal Brompton and Harefield NHS Trust, Sydney Street, London SW3 6NP, UK
J Cyst Fibros 2:61-8. 2003..Furthermore, older studies are becoming increasingly inapplicable as treatment and prognosis changes. Therefore, more research is needed in this field...
Inhaled ceftazidime compared with gentamicin and carbenicillin in older patients with cystic fibrosis infected with Pseudomonas aeruginosaR J Stead
Department of Cystic Fibrosis, Cardiothoracic Institute, London
Br J Dis Chest 81:272-9. 1987....
Cystic fibrosis-related diabetes: the role of peripheral insulin resistance and beta-cell dysfunctionB Yung
Department of Cystic Fibrosis and Chemical Pathology, Royal Brompton and Harefield NHS Trust, UK
Diabet Med 19:221-6. 2002....
Noninvasive ventilation in cystic fibrosis patients with acute or chronic respiratory failureB P Madden
Dept of Cardiothoracic Medicine, St George's Hospital, London, UK
Eur Respir J 19:310-3. 2002..For these patients, there is a possibility of prolonging life if they are successfully treated for their acute episode of respiratory failure until transplantation. In this group, treatment is not merely prolonging the process of dying...
Increased nitrotyrosine in exhaled breath condensate in cystic fibrosisB Balint
Dept of Thoracic Medicine, Imperial College School of Medicine at the National Heart and Lung Institute, London, UK
Eur Respir J 17:1201-7. 2001....
Cationic lipid-mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis: a double-blind placebo-controlled trialE W Alton
Department of Gene Therapy, Imperial College at National Heart and Lung Institute, London, UK
Lancet 353:947-54. 1999..We studied the safety and efficacy of this gene transfer to the lungs and nose of patients with cystic fibrosis in a double-blind placebo-controlled trial...
A cohort study of cystic fibrosis and malignancyC D Sheldon
Department of Cystic Fibrosis, Royal Brompton National Heart and Lung Hospital Chelsea, London, UK
Br J Cancer 68:1025-8. 1993..0001) during the period to mid 1991. On the basis of the present findings and previous case reports in the literature adenocarcinoma of the pancreas and adenocarcinoma of the terminal ileum may be associated with cystic fibrosis...
Heart lung transplantation for cystic fibrosisM E Hodson
Department of Cystic Fibrosis, Brompton Hospital, London, United Kingdom
Acta Univ Carol Med (Praha) 36:207-9. 1990..The physicians caring for CF patients in the UK are extremely grateful to our surgeons, Professor M Yacoub, Harefield and Brompton Hospitals, and Mr John Wallwork, Papworth Hospital, Cambridge for their pioneering work...
