Research Topics
| Timothy B HallettSummaryAffiliation: Imperial College Country: UK Publications
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Publications
Optimal uses of antiretrovirals for prevention in HIV-1 serodiscordant heterosexual couples in South Africa: a modelling studyTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, United Kingdom
PLoS Med 8:e1001123. 2011..Earlier ART and PrEP might both reduce HIV-1 transmission in this group, but the merits and synergies of these different approaches have not been analyzed...
Estimates of HIV incidence from household-based prevalence surveysTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, London, UK
AIDS 24:147-52. 2010..To estimate HIV incidence in the general population in countries where there have been two recent household-based HIV prevalence surveys (the Dominican Republic, Mali, Niger, Tanzania, and Zambia)...
Measuring and correcting biased child mortality statistics in countries with generalized epidemics of HIV infectionTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, London, W2 1PG, England
Bull World Health Organ 88:761-8. 2010....
Will circumcision provide even more protection from HIV to women and men? New estimates of the population impact of circumcision interventionsTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 87:88-93. 2011..However, these projections need revision to incorporate new data on the effect of male circumcision on the risk of acquiring and transmitting HIV...
Errors in 'BED'-derived estimates of HIV incidence will vary by place, time and ageTimothy B Hallett
Imperial College London, London, United Kingdom
PLoS ONE 4:e5720. 2009....
The role of testing and counselling for HIV prevention and care in the era of scaling-up antiretroviral therapyT B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, Norfolk Place, London, UK
Epidemics 1:77-82. 2009..HIV Testing and Counselling (TC) programmes are being scaled-up as part of efforts to provide universal access to antiretroviral treatment (ART)...
Estimating the HIV incidence rate: recent and future developmentsTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, London, UK
Curr Opin HIV AIDS 6:102-7. 2011..To describe the needs for information on the rate of new HIV infections (incidence) in epidemics and review developments in various methods for its estimation...
Estimating incidence from prevalence in generalised HIV epidemics: methods and validationTimothy B Hallett
Imperial College London, London, United Kingdom
PLoS Med 5:e80. 2008..Repeated cross-sectional measures of HIV prevalence are now becoming available for general populations in many countries, and we aim to develop and validate methods that use these data to estimate HIV incidence...
Understanding the impact of male circumcision interventions on the spread of HIV in southern AfricaTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom
PLoS ONE 3:e2212. 2008..We have used a mathematical model, parameterised using existing trial findings, to understand and predict the impact of circumcision programmes at the population level...
Estimating the resources required in the roll-out of universal access to antiretroviral treatment in ZimbabweT B Hallett
Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 87:621-8. 2011..Understanding how current practices relate to future resource requirements can help optimise ART programmes and inform long-term public health planning...
The impact of monitoring HIV patients prior to treatment in resource-poor settings: insights from mathematical modellingTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, United Kingdom
PLoS Med 5:e53. 2008..We investigated the potential influence of alternative patient management and ART initiation strategies on the impact of ART programmes in sub-Saharan Africa...
Measuring effectiveness in community randomized trials of HIV preventionT B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, UK
Int J Epidemiol 37:77-87. 2008..Complicated HIV transmission dynamics make it unclear how to design and interpret results from community-randomized controlled trials (CRCT) of interventions to prevent infection...
Age at first sex and HIV infection in rural ZimbabweTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London, UK
Stud Fam Plann 38:1-10. 2007..This finding can be explained by their having a greater lifetime number of sexual partners than those whose first sexual experience occurs later...
Behaviour change in generalised HIV epidemics: impact of reducing cross-generational sex and delaying age at sexual debutT B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 83:i50-54. 2007..The importance of reducing cross-generational sex (young women having sex with older men) and delaying age at first sex on the spread of HIV at the population-level has been presumed but not scientifically investigated and quantified...
Appropriate evaluation of HIV prevention interventions: from experiment to full-scale implementationTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 83:i55-60. 2007..Remarkably little is known about how best to reduce HIV incidence because most trials focus on the reduction of risk behaviours and assume an effect on HIV incidence...
Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban HaitiT B Hallett
Department of Infectious Disease Epidemiology, Imperial College, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 82:i1-8. 2006..To determine whether observed changes in HIV prevalence in countries with generalised HIV epidemics are associated with changes in sexual risk behaviour...
Estimating the risk of HIV transmission from homosexual men receiving treatment to their HIV-uninfected partnersTimothy B Hallett
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 87:17-21. 2011..To determine how the risk of HIV transmission from homosexual men receiving antiretroviral treatment is related to patterns of patient monitoring and condom use...
HIV decline associated with behavior change in eastern ZimbabweSimon Gregson
Department of Infectious Disease Epidemiology, Imperial College London, UK
Science 311:664-6. 2006..Sexually experienced men and women reported reductions in casual sex of 49 and 22%, respectively, whereas recent cohorts reported delayed sexual debut. Selective AIDS-induced mortality contributed to the decline in HIV prevalence...
Patterns of self-reported behaviour change associated with receiving voluntary counselling and testing in a longitudinal study from Manicaland, ZimbabweIde Cremin
Department of Infectious Disease Epidemiology, Imperial College London, St Marys Campus, Norfolk Place, Paddington, London, W2 1PG, UK
AIDS Behav 14:708-15. 2010..This study suggests that, among women, particularly those who are infected, behavioural risk reduction does occur following VCT...
Assessing adult mortality in HIV-1-afflicted Zimbabwe (1998 -2003)Ben A Lopman
Department of Infectious Disease Epidemiology, Imperial College London, England
Bull World Health Organ 84:189-97. 2006..To compare alternative methods to vital registration systems for estimating adult mortality, and describe patterns of mortality in Manicaland, Zimbabwe, which has been severely affected by HIV...
HIV decline in Zimbabwe due to reductions in risky sex? Evidence from a comprehensive epidemiological reviewSimon Gregson
Department of Infectious Disease Epidemiology, Imperial College London, London, UK
Int J Epidemiol 39:1311-23. 2010..We assessed the contributions of rising mortality, falling HIV incidence and sexual behaviour change to the decline in HIV prevalence...
Assessing evidence for behaviour change affecting the course of HIV epidemics: a new mathematical modelling approach and application to data from ZimbabweTimothy B Hallett
Imperial College London, London, UK
Epidemics 1:108-17. 2009..We aimed to develop a method to evaluate evidence for changes in risk behaviour altering the course of an HIV epidemic...
Condom use by female sex workers and their clients in Mexico: who decides and does it matter?Annick Bórquez
Department of Infectious Disease Epidemiology, Imperial College, London, UK
Sex Transm Infect 87:254-6. 2011..To explore the effect of different patterns of condom use by clients and female sex workers (FSW) on HIV transmission in Mexico...
Mathematical models in the evaluation of health programmesGeoffrey P Garnett
Department of Infectious Disease Epidemiology, Imperial College London, London, UK
Lancet 378:515-25. 2011..The degree of rigor in model development and assessment can vary greatly, and there is a danger that existing beliefs inappropriately influence judgments about model assumptions and results...
Concurrent sexual partnerships and primary HIV infection: a critical interactionJeffrey W Eaton
Department of Infectious Disease Epidemiology, Imperial College London, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
AIDS Behav 15:687-92. 2011..The sensitivity of epidemic spread to the amount of concurrency is greater than predicted by models that do not include primary HIV infection...
Evidence for changes in behaviour leading to reductions in HIV prevalence in urban MalawiGeorge Bello
Ministry of Health, Lilongwe, Malawi
Sex Transm Infect 87:296-300. 2011..At the epicentre of the HIV epidemic in Eastern Africa, HIV prevalence has appeared to stabilise in most countries. However, there are indications that the HIV epidemic in Malawi has recently declined...
Role of widows in the heterosexual transmission of HIV in Manicaland, Zimbabwe, 1998-2003B A Lopman
Department of Infectious Disease Epidemiology, Imperial College London, London, UK
Sex Transm Infect 85:i41-8. 2009..AIDS is the main driver of young widowhood in southern Africa...
Interpreting declines in HIV prevalence: impact of spatial aggregation and migration on expected declines in prevalenceP T Walker
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Sex Transm Infect 84:ii42-8. 2008..Declines in the prevalence of HIV might occur due to natural epidemic dynamics rather than changes in risk behaviour. Determining the cause of an observed decline is important in understanding the epidemiology of HIV...
Examining the promise of HIV elimination by 'test and treat' in hyperendemic settingsPeter J Dodd
Imperial College London, London, UK
AIDS 24:729-35. 2010....
Sex with stitches: assessing the resumption of sexual activity during the postcircumcision wound-healing periodPaul C Hewett
Population Council, Lusaka, Zambia
AIDS 26:749-56. 2012..This study uses observational data collected as part of Zambia's male circumcision program to measure sexual behavior in the postsurgical healing period and to model its influence on HIV transmission for men and their partners...
Late entry to HIV care limits the impact of anti-retroviral therapy in The NetherlandsColette Smit
HIV Monitoring Foundation Amsterdam, Amsterdam, The Netherlands
PLoS ONE 3:e1949. 2008..To explain differences in survival in the first three years of combination anti-retroviral therapy (cART) between HIV treatment centres in The Netherlands...
