Geoff A Butcher

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria
    Quinton L Fivelman
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Malar J 1:1. 2002
  2. ncbi Malaria and macrophage function in Africans: a possible link with autoimmune disease?
    G A Butcher
    Department of Biology, Imperial College of Science, Technology and Medicine, London, UK
    Med Hypotheses 47:97-100. 1996
  3. ncbi Antimalarial drugs and the mosquito transmission of Plasmodium
    G A Butcher
    Department of Biology, Imperial College of Science, Technology and Medicine, London, U K
    Int J Parasitol 27:975-87. 1997
  4. ncbi Inhibition of the mosquito transmission of Plasmodium berghei by Malarone (atovaquone-proguanil)
    G A Butcher
    Department of Biology, Imperial College of Science, Technology and Medicine, London, U K
    Ann Trop Med Parasitol 94:429-36. 2000
  5. ncbi Persistence of atovaquone in human sera following treatment: inhibition of Plasmodium falciparum development in vivo and in vitro
    Geoff A Butcher
    Department of Biologic Sciences, Imperial College of Science Technology and Medicine, London, UK
    Am J Trop Med Hyg 68:111-4. 2003
  6. ncbi Maintenance of the Plasmodium berghei life cycle
    Robert E Sinden
    Department of Biology, Imperial College of Science, Technology and Medicine, London, UK
    Methods Mol Med 72:25-40. 2002
  7. ncbi A malaria scavenger receptor-like protein essential for parasite development
    Charles Claudianos
    Department of Biological Sciences, Imperial College of Science Technology and Medicine, London, UK
    Mol Microbiol 45:1473-84. 2002
  8. ncbi Complete development of mosquito phases of the malaria parasite in vitro
    Ebtesam M Al-Olayan
    Centre for Applied Entomology and Parasitology, School of Life Sciences, Keele University, Staffordshire ST5 5BG, UK
    Science 295:677-9. 2002
  9. ncbi Progression of Plasmodium berghei through Anopheles stephensi is density-dependent
    Robert E Sinden
    Division of Cell and Molecular Biology, Faculty of Life Sciences, Imperial College London, London, United Kingdom
    PLoS Pathog 3:e195. 2007

Collaborators

Detail Information

Publications9

  1. ncbi Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria
    Quinton L Fivelman
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Malar J 1:1. 2002
    ..The cytochrome b gene of isolate NGATV01 showed a single mutation, Tyr268Asn which has not been seen previously...
  2. ncbi Malaria and macrophage function in Africans: a possible link with autoimmune disease?
    G A Butcher
    Department of Biology, Imperial College of Science, Technology and Medicine, London, UK
    Med Hypotheses 47:97-100. 1996
    ..It is argued here that malaria both prevents these diseases in West Africa by its effects on macrophage function, and has also selected for a predisposition to them...
  3. ncbi Antimalarial drugs and the mosquito transmission of Plasmodium
    G A Butcher
    Department of Biology, Imperial College of Science, Technology and Medicine, London, U K
    Int J Parasitol 27:975-87. 1997
    ..This review summarises the available information on the properties of antimalarials in relation to mosquito transmission and highlights the need for more attention to be paid to this aspect of drug action...
  4. ncbi Inhibition of the mosquito transmission of Plasmodium berghei by Malarone (atovaquone-proguanil)
    G A Butcher
    Department of Biology, Imperial College of Science, Technology and Medicine, London, U K
    Ann Trop Med Parasitol 94:429-36. 2000
    ..Despite previous information on the rapid elimination of atovaquone by patients, the present data indicate that low concentrations of this drug may persist in the plasma for some weeks after treatment...
  5. ncbi Persistence of atovaquone in human sera following treatment: inhibition of Plasmodium falciparum development in vivo and in vitro
    Geoff A Butcher
    Department of Biologic Sciences, Imperial College of Science Technology and Medicine, London, UK
    Am J Trop Med Hyg 68:111-4. 2003
    ..Also, persistence of atovaquone in plasma at low concentrations for long periods may increase the risk of resistant parasites arising...
  6. ncbi Maintenance of the Plasmodium berghei life cycle
    Robert E Sinden
    Department of Biology, Imperial College of Science, Technology and Medicine, London, UK
    Methods Mol Med 72:25-40. 2002
  7. ncbi A malaria scavenger receptor-like protein essential for parasite development
    Charles Claudianos
    Department of Biological Sciences, Imperial College of Science Technology and Medicine, London, UK
    Mol Microbiol 45:1473-84. 2002
    ..berghei results in parasites that form normal numbers of oocysts, but fail to produce any sporozoites. We suggest that, in addition to a role in sporogonic development, PxSR may have a multiplicity of functions...
  8. ncbi Complete development of mosquito phases of the malaria parasite in vitro
    Ebtesam M Al-Olayan
    Centre for Applied Entomology and Parasitology, School of Life Sciences, Keele University, Staffordshire ST5 5BG, UK
    Science 295:677-9. 2002
    ..Sporozoite production required the presence of para-aminobenzoic acid. The entire life cycle of P. berghei, a useful model malaria parasite, can now be achieved in vitro...
  9. ncbi Progression of Plasmodium berghei through Anopheles stephensi is density-dependent
    Robert E Sinden
    Division of Cell and Molecular Biology, Faculty of Life Sciences, Imperial College London, London, United Kingdom
    PLoS Pathog 3:e195. 2007
    ....