D Christopher Braddock

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi A hypothesis concerning the biosynthesis of the obtusallene family of marine natural products via electrophilic bromination
    D Christopher Braddock
    Department of Chemistry, Imperial College London, London SW7 2AZ, UK
    Org Lett 8:6055-8. 2006
  2. ncbi A biosynthetically-inspired synthesis of the tetrahydrofuran core of obtusallenes II and IV
    D Christopher Braddock
    Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, U K
    Org Lett 9:445-8. 2007
  3. ncbi Bromonium ion induced transannular oxonium ion formation-fragmentation in model obtusallene systems and structural reassignment of obtusallenes V-VII
    D Christopher Braddock
    Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, UK
    J Org Chem 74:1835-41. 2009
  4. ncbi Enantiospecific bromonium ion generation and intramolecular capture: a model system for asymmetric bromonium ion-induced polyene cyclisations
    D Christopher Braddock
    Department of Chemistry, Imperial College London, London, SW7 2AZ, UK
    Chem Commun (Camb) 47:9051-3. 2011
  5. ncbi Total synthesis of the marine metabolite (±)-polysiphenol via highly regioselective intramolecular oxidative coupling
    Tim N Barrett
    Department of Chemistry, Imperial College London, London, South Kensington SW7 2AZ, UK
    J Nat Prod 74:1980-4. 2011
  6. ncbi Structural reassignment of obtusallenes V, VI, and VII by GIAO-based density functional prediction
    D Christopher Braddock
    Department of Chemistry, Imperial College London, London, UK
    J Nat Prod 71:728-30. 2008

Collaborators

  • Tim N Barrett
  • Michael R Webb
  • Anna Monta
  • Andrew J P White

Detail Information

Publications6

  1. ncbi A hypothesis concerning the biosynthesis of the obtusallene family of marine natural products via electrophilic bromination
    D Christopher Braddock
    Department of Chemistry, Imperial College London, London SW7 2AZ, UK
    Org Lett 8:6055-8. 2006
    ..Structure: see text] A hypothesis concerning the biosynthesis of the marine natural product family the obtusallenes is proposed. Multiple electrophilic bromination events are invoked...
  2. ncbi A biosynthetically-inspired synthesis of the tetrahydrofuran core of obtusallenes II and IV
    D Christopher Braddock
    Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, U K
    Org Lett 9:445-8. 2007
    ..Bromoetherification gave the fully elaborated core of obtusallenes II and IV with all of the relative stereochemistry correctly set...
  3. ncbi Bromonium ion induced transannular oxonium ion formation-fragmentation in model obtusallene systems and structural reassignment of obtusallenes V-VII
    D Christopher Braddock
    Department of Chemistry, Imperial College London, South Kensington, London SW7 2AZ, UK
    J Org Chem 74:1835-41. 2009
    ..This revised structure was subsequently confirmed by X-ray crystallography. These findings allow us to confidently conclude that the structures of obtusallenes VII and VI should also be reassigned...
  4. ncbi Enantiospecific bromonium ion generation and intramolecular capture: a model system for asymmetric bromonium ion-induced polyene cyclisations
    D Christopher Braddock
    Department of Chemistry, Imperial College London, London, SW7 2AZ, UK
    Chem Commun (Camb) 47:9051-3. 2011
    ..This enantiospecific pathway is not significantly perturbed by the addition of a trisubstituted alkene...
  5. ncbi Total synthesis of the marine metabolite (±)-polysiphenol via highly regioselective intramolecular oxidative coupling
    Tim N Barrett
    Department of Chemistry, Imperial College London, London, South Kensington SW7 2AZ, UK
    J Nat Prod 74:1980-4. 2011
    ..The origins of the regioselectivity in the oxidative coupling are explored...
  6. ncbi Structural reassignment of obtusallenes V, VI, and VII by GIAO-based density functional prediction
    D Christopher Braddock
    Department of Chemistry, Imperial College London, London, UK
    J Nat Prod 71:728-30. 2008
    ..Revised structures proposed previously for obtusallenes V-VII ( 5- 7) have been confirmed on the basis of computed GIAO-DFT 13C NMR chemical shifts...