S P McKenna

..The international development of the Parents' Index of Quality of Life in Atopic Dermatitis (PIQoL-AD), a quality of life (QoL) instrument specific to parents of children with atopic dermatitis (AD) is described...

..In particular it is important to establish unidimensionality, additivity and item ordering through the application of Item Response Theory...

..We developed and evaluated the psychometric performance of a patient-reported measure to assess the impact on sleep due to respiratory disease, the COPD and Asthma Sleep Impact Scale (CASIS)...

..The Ankylosing Spondylitis Quality of Life (ASQOL) questionnaire is a unidimensional, disease-specific measure developed in the UK and the Netherlands. This study describes its adaptation into other languages...

..We followed 982 clinically depressed persons to determine which measures changed and whether the change was synchronous with change in depressive symptoms...

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..Health and Quality of Life Outcomes 2009, 7: 6...

..The new model is illustrated by data collected using different types of outcome measures. Finally, the different outcomes are related to their purpose in clinical studies...

..The purpose of this study was to develop and validate a preference based measure from the CAMPHOR that could be used in cost-utility analyses...

..This review looks at these developments and reports on recently published articles on the impact of the condition on affected children and other members of their family...

..To report on quality of life (QoL) and health-related quality of life (HRQL) impacts of pimecrolimus (Elidel, Novartis A.G., Basel, Switzerland, SDZ ASM 981) 1% cream in the long-term treatment of paediatric atopic dermatitis...

..The aim of the study was to develop health-related quality of life (symptoms and functioning) scales and a quality of life scale that would allow comprehensive, accurate and valid patient-reported outcome assessment in clinical studies...

..The aim of the current study was to produce and validate a conceptually equivalent US version of the PSORIQoL with equally good psychometric properties...

..From these it was intended to develop two separate scales, one assessing impact on carers and the other determining the effect on the child...

..This study describes the adaptation of eight language versions for Canadian English, Canadian French, French, German, Italian, Spanish, Swedish, and US English...

..The present study describes the adaptation of the QoL-AGHDA for use in the following four Slavic languages; Czech, Polish, Serbian and Slovakian...

..The present article questions these orthodox views and suggests alternative approaches that have been shown to be effective...

..The purpose of the study was to develop a patient-based PRO measure for COPD that captures the overall everyday impact of living with COPD from the patient's perspective...

..Several patient-completed instruments are available to measure outcome in dermatological conditions but these primarily focus on severity of disease rather than on QoL...

..Patient reported outcome measures used in studies of psoriatic arthritis (PsA) have been found to be inadequate for determining the impact of the disease from the patient's perspective...

..This paper describes the development and testing of a new instrument to measure QoL in systemic lupus erythematosus (L-QoL)...

..This paper describes the production and psychometric assessment of nine new language versions for Canada (French and English), Denmark, France, Germany, Italy, Morocco, Spain and the US...

..The CAMPHOR Utility Index is valid and responsive to change. Patients can experience significant and important improvements even if they do not improve on the basis of traditional outcomes, such as NYHA functional class...

..CONCLUSIONS: The QoLIAD is a practical, reliable, valid and culturally applicable instrument for measuring the impact of AD and its treatment on QoL in clinical trials or in routine clinical practice...

..Although disease-specific health status measures are available for ankylosing spondylitis (AS), no instrument exists for assessing quality of life (QoL) in the condition...

..The multidimensional assessment of fatigue is complicated by the interrelation of its multiple causes and effects...

..This report describes the validation of paper-and-pencil versions of the scales and responsiveness assessments in an Australian clinical trial...

..Complex diseases such as multiple sclerosis (MS) present dilemmas over the choice of patient-reported outcome measures as no single scale can inform on all types of MS impact from the patient's perspective...

..It is argued that it would be useful for clinicians to gain an understanding of the meaning of QoL scores through routine use of such measures in clinical practice...

..The Herpes Outbreak Impact Questionnaire (HOIQ) and the Herpes Symptom Checklist (HSC) were designed to be acceptable to clinical professionals and to reflect patients' experience...

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..The objective is to produce eight new language versions of the U-FIS: Canadian-English, Canadian-French, French, German, Italian, Spanish, Swedish, and US-English...

..A secondary aim of both trials, and the focus of this article, was to evaluate the quality-of-life (QoL) impact of pimecrolimus compared with its vehicle...

..Needs-based instruments have been developed for a wide range of diseases. Recently, they have been applied widely in dermatology. This paper describes these applications and shows how they have proved of value...

..Needs-based QoL is defined and it is argued that this approach (the extent to which an individual is able to meet his or her needs) provides a good working indicator of QoL...

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..It was developed in the UK and US and has proven to be acceptable to patients, to have good psychometric properties, and to be unidimensional...

..Quantification with disease-specific patient-reported outcome measures is essential for assessing disease severity. This study aimed to develop and validate the first scar-specific patient-reported outcome measure...

..However, the patient-reported outcome measures used in clinical studies were not lipoatrophy-specific and had limited ability to show real changes in health status associated with lipoatrophy...

..Current asthma patient-reported outcome (PRO) measures focus on symptoms and functioning and may not capture the holistic impact of asthma on the quality of life of the patient...

..Although promising, both questionnaires warrant further developmental work and stronger support of measurement validity before they could be considered fully suitable for valid use in PD, in particular in earlier stages of the disease...

..Different sections of the Japanese NHP were shown to have known group validity...

..The psychometric properties of instruments designed to measure the impact of psoriasis should be tested in populations in which the instrument is to be applied...

..Predicted convergent and divergent validity was demonstrated. Unidimensionality of the instrument was confirmed by excellent fit to the Rasch model. The RAQoL is appropriate for use in clinical studies and trials involving RA patients...

..To enable use in the United States, this study adapted, field-tested, and evaluated its reliability and validity at a single center in Chicago...

..The new language version was shown to be well-accepted by respondents and to have excellent psychometric properties...

..The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) is the first disease-specific instrument for assessing patient-reported symptoms, functioning and quality of life (QoL) in pulmonary arterial hypertension (PAH)...

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..By ensuring that scales are based on the same measurement model and that they fit the Rasch model it is possible for QoL scores to be compared across diseases by means of cocalibration and item banking...

..To develop and validate a disease-specific quality of life (QOL) measure for osteoarthritis (OA), the OAQoL, using the needs-based conceptual model...

..This preliminary study illustrates the need for documented linguistic validity before new language adaptations of patient-reported outcome measures can be considered suitable for use in clinical trials, research, and practice...

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