Aftab AlaSummaryAffiliation: Frimley Park Hospital Country: UK Publications
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Publications
Wilson's diseaseAftab Ala
UCL Institute of Hepatology, Hampstead Campus, Division of Medicine, Royal Free and University College Medical School, University College London, London, UK
Lancet 369:397-408. 2007..Liver transplantation corrects the underlying pathophysiology and can be lifesaving. The discovery of the Wilson's disease gene has opened up a new molecular diagnostic approach, and could form the basis of future gene therapy...
Wilson disease: pathophysiology, diagnosis, treatment, and screeningAftab Ala
Division of Liver Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
Clin Liver Dis 8:787-805, viii. 2004..Future cell-based and genetic therapies may provide a cure for this disorder...
Histopathology and clinical correlates of end-stage hepatitis B cirrhosis: a possible mechanism to explain the response to antiviral therapySamuel H Sigal
Center for Liver Disease and Transplantation, New York Weill Cornell Medical Center, 525 East 68th Street, Box 308, New York, NY 10021, USA
Liver Transpl 11:82-8. 2005..In conclusion, high-grade inflammation is common in end-stage HBV cirrhosis, but it is not readily detected by biochemical and virologic parameters. High-grade inflammation is associated with a greater degree of hepatic decompensation...
Wilson disease in septuagenarian siblings: Raising the bar for diagnosisAftab Ala
Division of Liver Diseases, Recanati/Miller Transplant Institute, The Mount Sinai Medical Center, New York, NY, USA
Hepatology 41:668-70. 2005..Environmental and extragenic factors are pivotal determinants of disease phenotype. We suggest that WD must be considered at all ages in patients with hepatic disease, neurological disease, or psychiatric symptoms...
