Research Topics
| S P ElliottSummaryCountry: UK Publications
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Detail Information
Publications
The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosisSimon Elliott
ROAR Forensics, Malvern Hills Science Park, Malvern, UK
Forensic Sci Int 198:53-7. 2010..Initial data suggest vitreous humour BHB could be a useful alternative in the absence of blood (same interpretative ranges may also apply). Analytical recommendation for investigation of post-mortem ketoacidosis is also presented...
Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPPSimon Elliott
Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham, B18 7QH United Kingdom
J Anal Toxicol 32:172-7. 2008..Although BZP and 3-TFMPP were not the direct cause of death, the toxicological findings presented in this paper may assist the interpretation of future cases involving these drugs where their significance may be more apparent...
Nonfatal instances of intoxication with gamma-hydroxybutyrate in the United KingdomSimon P Elliott
Regional Laboratory for Toxicology, City Hospital, Birmingham B18 7QH, UK
Ther Drug Monit 26:432-40. 2004..This is believed to be the largest compilation of nonfatal cases from the United Kingdom...
Current awareness of piperazines: pharmacology and toxicologySimon Elliott
Forensics Ltd, Malvern Hills Science Park, Geraldine Road, Malvern, Worcestershire WR14 3SZ, UK
Drug Test Anal 3:430-8. 2011..This paper reviews the current pharmacological and toxicological information for piperazine derivatives and also includes new ante-mortem and post-mortem blood data...
The prevalence of drugs and alcohol found in road traffic fatalities: a comparative study of victimsSimon Elliott
ROAR Forensics Ltd Malvemrn Hills Science Park, Geraldine Road, Malvemrn, Worcestershire, WR14 3SZ, UK
Sci Justice 49:19-23. 2009..This degree of frequency strongly implicates the involvement of drugs and alcohol in road traffic incidents and infers an effect on driving ability and individual impairment...
Investigative implications of the instability and metabolism of mebeverineSimon Elliott
Regional Laboratory for Toxicology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham B18 7QH, United Kingdom
J Anal Toxicol 30:91-7. 2006..Only one case involving mebeverine has previously been published; this paper provides additional data and suggestions of best practice for case investigation...
MDMA and MDA concentrations in antemortem and postmortem specimens in fatalities following hospital admissionSimon P Elliott
Regional Laboratory for Toxicology, City Hospital N H S Trust, Birmingham, UK
J Anal Toxicol 29:296-300. 2005..Overall, MDMA and MDA appear to exhibit postmortem redistribution and concentrations measured in postmortem specimens (even from peripheral sites) are not directly comparable with antemortem findings close to or prior to death...
The presence of gamma-hydroxybutyric acid (GHB) and gamma-butyrolactone (GBL) in alcoholic and non-alcoholic beveragesSimon Elliott
Regional Laboratory for Toxicology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham B187QH, UK
Forensic Sci Int 151:289-92. 2005..This is believed to be the first published data concerning the endogenous presence of GHB and GBL in the beverages described...
The possible influence of micro-organisms and putrefaction in the production of GHB in post-mortem biological fluidSimon Elliott
Regional Laboratory for Toxicology, City Hospital, Dudley Road, Birmingham B18 7QH, UK
Forensic Sci Int 139:183-90. 2004..Although this concentration is lower than is typically associated with "endogenous" post-mortem GHB concentrations, this paper proposes a potential microbial production of GHB with time...
Further evidence for the presence of GHB in postmortem biological fluid: implications for the interpretation of findingsSimon P Elliott
Regional Laboratory for Toxicology, City Hospital N H S Trust, Dudley Road, Birmingham B18 7QH, United Kingdom
J Anal Toxicol 28:20-6. 2004..At blood concentrations less than 30 mg/L and at urine concentrations less than 20 mg/L, it is possible that any GHB detected could represent only endogenous GHB production...
Gamma hydroxybutyric acid (GHB) concentrations in humans and factors affecting endogenous productionSimon P Elliott
Regional Laboratory for Toxicology, City Hospital N H S Trust, Dudley Road, Birmingham B18 7QH, UK
Forensic Sci Int 133:9-16. 2003....
Analysis of 4-methylthioamphetamine in clinical specimensS P Elliott
Regional Laboratory for Toxicology, City Hospital NHS Trust, Birmingham, UK
Ann Clin Biochem 38:339-47. 2001..This paper describes the first reported data regarding possible pharmacokinetics of 4-MTA in humans and presents the first reported non-fatal instances of 4-MTA intoxication in the UK...
A previously unidentified acepromazine metabolite in humans: implications for the measurement of acepromazine in bloodS P Elliott
Regional Laboratory for Toxicology, City Hospital NHS Teaching Trust, Birmingham, United Kingdom
J Anal Toxicol 23:367-71. 1999..These findings have important implications for the analytical toxicology of acepromazine...
A validated hybrid quadrupole linear ion-trap LC-MS method for the analysis of morphine and morphine glucuronides applied to opiate deathsKerry Taylor
Regional Laboratory for Toxicology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham B187QH, UK
Forensic Sci Int 187:34-41. 2009..e. illicit heroin) and the rapidity of death after administration...
A case of fatal poisoning with the aconite plant: quantitative analysis in biological fluidS P Elliott
Regional Laboratory for Toxicology, City Hospital N.H.S. Teaching Trust, Dudley Road, Birmingham B18 7QH, United Kingdom
Sci Justice 42:111-5. 2002..Hence, accidental, suicidal or homicidal poisoning due to the ingestion of plant material remains a possibility and should be borne in mind when investigating sudden or unexplained death...
Clinical urinalysis of drugs and alcohol in instances of suspected surreptitious administration ("spiked drinks")Simon P Elliott
Regional Laboratory for Toxicology, Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Dudley Road, Birmingham, B18 7QH, UK
Sci Justice 45:129-34. 2005..6% of cases), ephedrine 0.6% of cases), fluoxetine (0.6% of cases), tramadol (0.6% of cases) and zopiclone (0.6% of cases). No gamma-hydroxybutyrate (GHB), gamma-butyrolactone (GBL) or flunitrazepam was detected in the cases analysed...
