Research Topics
| William J CunliffeSummaryCountry: UK Publications
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Detail Information
Publications
Looking back to the future--acneW J Cunliffe
Skin Research Centre, Department of Dermatology, The General Infirmary at Leeds, UK
Dermatology 204:167-72. 2002
Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responsesJenny Kim
Division of Dermatology, University of California, Los Angeles, School of Medicine, Los Angeles, CA 90095, USA
J Immunol 169:1535-41. 2002..These data suggest that P. acnes triggers inflammatory cytokine responses in acne by activation of TLR2. As such, TLR2 may provide a novel target for treatment of this common skin disease...
A randomized, double-blind comparison of a clindamycin phosphate/benzoyl peroxide gel formulation and a matching clindamycin gel with respect to microbiologic activity and clinical efficacy in the topical treatment of acne vulgarisWilliam J Cunliffe
Department of Dermatology, The General Infirmary, Leeds, United Kingdom
Clin Ther 24:1117-33. 2002..These reductions in total P acnes and clindamycin-resistant P acnes counts correlated with reductions in total acne lesions...
Inflammatory events are involved in acne lesion initiationAnthony H T Jeremy
University of Leeds, and Leeds General Infirmary, Leeds, UK
J Invest Dermatol 121:20-7. 2003..These results provide novel evidence for vascular endothelial cell activation and involvement of inflammatory responses in the very earliest stages of acne lesion development...
Comedone formation: etiology, clinical presentation, and treatmentWilliam J Cunliffe
Skin Research Centre, University of Leeds, Leeds, UK
Clin Dermatol 22:367-74. 2004..The glass slide is gently removed, taking with it the upper part of the stratum corneum and microcomedones, which are then analyzed by low-power microscopy or digital image analysis.(1-3)..
Is combined oral and topical therapy better than oral therapy alone in patients with moderate to moderately severe acne vulgaris? A comparison of the efficacy and safety of lymecycline plus adapalene gel 0.1%, versus lymecycline plus gel vehicleWilliam J Cunliffe
Department of Dermatology, The General Infirmary at Leeds, UK
J Am Acad Dermatol 49:S218-26. 2003....
A randomized double-blind study to assess the effects of silicic acid compared to placebo in patients with mild to moderate acneCatherine Fernandez
Clinical Trials Unit, Leeds Foundation for Dermatological Research, Department of Dermatology, General Infirmary at Leeds, Leeds, UK
J Dermatolog Treat 16:287-94. 2005..To establish the efficacy and safety of silicic acid in comparison to placebo in patients with mild to moderate acne vulgaris...
Randomised, controlled trial of the efficacy and safety of adapalene gel 0.1% and tretinoin cream 0.05% in patients with acne vulgarisWilliam J Cunliffe
Departement of Dermatology, General Infirmary, Leeds, UK
Eur J Dermatol 12:350-4. 2002..CONCLUSION: Adapalene gel 0.1% showed equivalent efficacy and was significantly better tolerated than tretinoin cream 0.05% in patients with mild-to-moderate acne vulgaris...
Guidelines for treating acneAndreas D Katsambas
Department of Dermatology, University of Athens, Andreas Sygros Hospital, 5 Ionos Dragoumi Street, Athens, Greece
Clin Dermatol 22:439-44. 2004..3) Effective treatment can dramatically improve a person's quality of life...
Comparison of five antimicrobial regimens for treatment of mild to moderate inflammatory facial acne vulgaris in the community: randomised controlled trialMara Ozolins
Centre of Evidence-Based Dermatology, Queens Medical Centre, Nottingham, UK
Lancet 364:2188-95. 2004..INTERPRETATION: Topical benzoyl peroxide and benzoyl peroxide/erythromycin combinations are similar in efficacy to oral oxytetracycline and minocycline and are not affected by propionibacterial antibiotic resistance...
A new concept for acne therapy: a pilot study with zileuton, an oral 5-lipoxygenase inhibitorChristos C Zouboulis
Arch Dermatol 139:668-70. 2003
Validation of the CR-POSSUM risk-adjusted scoring system for major colorectal cancer surgery in a single centerStephen J Bromage
Queen Elizabeth Hospital, Gateshead, Tyne and Wear, UK
Dis Colon Rectum 50:192-6. 2007..We also analyzed whether albumin may have a role in the CR-POSSUM model...
