Edward T Wargent

Summary

Affiliation: Clore Laboratory
Country: UK

Publications

  1. ncbi Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation
    Ed Wargent
    Clore Laboratory for Life Sciences, University of Buckingham, Buckingham, MK18 1EG, UK
    Lipids Health Dis 4:3. 2005
  2. ncbi The measurement of insulin secretion using pancreas perfusion in the rodent
    Edward T Wargent
    Clore Laboratory, University of Buckingham, Hunter Street, Buckingham, MK18 1EG, UK
    Methods Mol Biol 560:203-19. 2009
  3. ncbi Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter
    Nigel J Pearce
    Department of Vascular Biology, GlaxoSmithKline, Harlow, UK
    Metabolism 53:1322-30. 2004
  4. ncbi Prevention of diet-induced obesity and impaired glucose tolerance in rats following administration of leptin to their mothers
    Claire J Stocker
    Clore Laboratory, Univ of Buckingham, Buckingham, UK
    Am J Physiol Regul Integr Comp Physiol 292:R1810-8. 2007
  5. ncbi Inhibition of insulin secretion by betagranin, an N-terminal chromogranin A fragment
    Gerhard M Schmid
    Biomedical Proteomics Research Group BPRG, Department of Structural Biology and Bioinformatics, Geneva University Medical Center, CH 1211 Geneva 4, Switzerland
    J Biol Chem 282:12717-24. 2007

Collaborators

  • Jonathan R S Arch
  • Steven Wang
  • J Speakman
  • Stephen A Smith
  • John C Clapham
  • Claire J Stocker
  • Gerhard M Schmid
  • Nigel J Pearce
  • Dorothee Caille
  • Jean Charles Sanchez
  • Denis F Hochstrasser
  • Paolo Meda
  • Jean-Charles Sanchez
  • Michael A Cawthorne
  • Colleen M Taylor
  • Matthew P Coghlan
  • Carolyn A Lister
  • Alastair D Morrison
  • John W Yates
  • Stacey L Corcoran
  • Gregory J Murphy
  • Lynne Roxbee-Cox
  • Alexander J Harper
  • Julie C Holder
  • Alejandro Abuin
  • Gary B Moore
  • Andrea Llano

Detail Information

Publications5

  1. ncbi Prolonged treatment of genetically obese mice with conjugated linoleic acid improves glucose tolerance and lowers plasma insulin concentration: possible involvement of PPAR activation
    Ed Wargent
    Clore Laboratory for Life Sciences, University of Buckingham, Buckingham, MK18 1EG, UK
    Lipids Health Dis 4:3. 2005
    ..We have conducted three experiments with CLA in obese mice over three weeks, and one over eleven weeks. We have also investigated the effects of CLA isomers in PPARgamma and PPARalpha reporter gene assays...
  2. ncbi The measurement of insulin secretion using pancreas perfusion in the rodent
    Edward T Wargent
    Clore Laboratory, University of Buckingham, Hunter Street, Buckingham, MK18 1EG, UK
    Methods Mol Biol 560:203-19. 2009
    ..A detailed description of the isolation and perfusion apparatus is described as well as the measurement of glucose-stimulated insulin secretion using an in-house-developed radioimmunoassay...
  3. ncbi Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter
    Nigel J Pearce
    Department of Vascular Biology, GlaxoSmithKline, Harlow, UK
    Metabolism 53:1322-30. 2004
    ....
  4. ncbi Prevention of diet-induced obesity and impaired glucose tolerance in rats following administration of leptin to their mothers
    Claire J Stocker
    Clore Laboratory, Univ of Buckingham, Buckingham, UK
    Am J Physiol Regul Integr Comp Physiol 292:R1810-8. 2007
    ..A similar trend was seen for male rats fed on the obesogenic diet. Thus leptin levels during pregnancy and lactation can affect the development of energy balance regulatory systems in their offspring...
  5. ncbi Inhibition of insulin secretion by betagranin, an N-terminal chromogranin A fragment
    Gerhard M Schmid
    Biomedical Proteomics Research Group BPRG, Department of Structural Biology and Bioinformatics, Geneva University Medical Center, CH 1211 Geneva 4, Switzerland
    J Biol Chem 282:12717-24. 2007
    ..The data demonstrated a hitherto unknown inhibitory effect of betagranin on insulin secretion...