Svend K Petersen-Mahrt

Summary

Affiliation: Cancer Research UK
Country: UK

Publications

  1. ncbi DNA deamination in immunity
    Svend Petersen-Mahrt
    DNA Editing Laboratory, Cancer Research UK, Clare Hall Laboratories, South Mimms Hert, UK
    Immunol Rev 203:80-97. 2005
  2. ncbi DNA deaminases: AIDing hormones in immunity and cancer
    Svend K Petersen-Mahrt
    DNA Editing Laboratory, Clare Hall Laboratories, London Research Institute, South Mimms, EN6 3LD, UK
    J Mol Med (Berl) 87:893-7. 2009
  3. ncbi Estrogen directly activates AID transcription and function
    Siim Pauklin
    DNA Editing Laboratory, Cancer Research UK, Clare Hall Laboratories, South Mimms, EN6 3LD, England, UK
    J Exp Med 206:99-111. 2009
  4. ncbi Progesterone inhibits activation-induced deaminase by binding to the promoter
    Siim Pauklin
    DNA Editing Lab, Clare Hall Laboratories, Cancer Research U K, South Mimms, United Kingdom
    J Immunol 183:1238-44. 2009
  5. ncbi The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action
    Heather A Coker
    DNA Editing Lab, Clare Hall Laboratories, Cancer Research UK, South Mimms EN6 3LD, UK
    DNA Repair (Amst) 6:235-43. 2007
  6. ncbi Genetic and in vitro assays of DNA deamination
    Heather A Coker
    DNA Editing Laboratory, Cancer Research United Kingdom, Clare Hall Laboratories, South Mimms, Hertfordshire
    Methods Enzymol 408:156-70. 2006

Collaborators

  • Siim Pauklin
  • Heather A Coker
  • Gudrun Bachmann
  • Almudena R Ramiro
  • Isora V Sernández
  • Hugh D Morgan

Detail Information

Publications6

  1. ncbi DNA deamination in immunity
    Svend Petersen-Mahrt
    DNA Editing Laboratory, Cancer Research UK, Clare Hall Laboratories, South Mimms Hert, UK
    Immunol Rev 203:80-97. 2005
    ....
  2. ncbi DNA deaminases: AIDing hormones in immunity and cancer
    Svend K Petersen-Mahrt
    DNA Editing Laboratory, Clare Hall Laboratories, London Research Institute, South Mimms, EN6 3LD, UK
    J Mol Med (Berl) 87:893-7. 2009
    ..Identifying the direct molecular link between estrogen and a mutation event provides us with new targets for studying and possibly inhibiting the pathological side-effects of estrogen...
  3. ncbi Estrogen directly activates AID transcription and function
    Siim Pauklin
    DNA Editing Laboratory, Cancer Research UK, Clare Hall Laboratories, South Mimms, EN6 3LD, England, UK
    J Exp Med 206:99-111. 2009
    ..We therefore suggest that estrogen-induced autoimmunity and oncogenesis may be derived through AID-dependent DNA instability...
  4. ncbi Progesterone inhibits activation-induced deaminase by binding to the promoter
    Siim Pauklin
    DNA Editing Lab, Clare Hall Laboratories, Cancer Research U K, South Mimms, United Kingdom
    J Immunol 183:1238-44. 2009
    ..Importantly, the progesterone-induced repression was also extended to the protein level of AID and its activity on somatic hypermutation and class switch recombination...
  5. ncbi The nuclear DNA deaminase AID functions distributively whereas cytoplasmic APOBEC3G has a processive mode of action
    Heather A Coker
    DNA Editing Lab, Clare Hall Laboratories, Cancer Research UK, South Mimms EN6 3LD, UK
    DNA Repair (Amst) 6:235-43. 2007
    ....
  6. ncbi Genetic and in vitro assays of DNA deamination
    Heather A Coker
    DNA Editing Laboratory, Cancer Research United Kingdom, Clare Hall Laboratories, South Mimms, Hertfordshire
    Methods Enzymol 408:156-70. 2006
    ..The application of these assays to future studies of the deaminase family will provide an indispensible tool in determining the potentially diverse functions of the remainder of this family of enzymes...