Research Topics
| Natalie C DirekzeSummaryAffiliation: Cancer Research UK Country: UK Publications
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Detail Information
Publications
Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblasts in bone-marrow-transplanted miceNatalie C Direkze
Histopathology Unit, Cancer Research UK London Research Institute, London, United Kingdom
Stem Cells 21:514-20. 2003..005). Bone-marrow-derived fibroblasts were also found. We suggest that bone marrow contributes to a circulating population of cells and, in the context of injury, these cells are recruited and contribute to tissue repair...
Bone marrow contribution to tumor-associated myofibroblasts and fibroblastsNatalie C Direkze
Cancer Research United Kingdom, London Research Institute, London, UK
Cancer Res 64:8492-5. 2004..Thus, the development of tumor stroma is at least in part a systemic response that may ultimately yield methods of targeting new therapy...
Bone marrow-derived stromal cells express lineage-related messenger RNA speciesNatalie C Direkze
Cancer Research UK, 44 Lincolns Inn Fields, London WC2A 3PX, UK
Cancer Res 66:1265-9. 2006..This provides evidence that the bone marrow-tumor stroma axis is functionally relevant and may therefore subsequently be exploited to develop new strategies for anticancer therapy...
Plastic adult stem cells: will they graduate from the school of hard knocks?Malcolm R Alison
Histopathology Unit, Cancer Research UK, London WC2A 3PX, UK
J Cell Sci 116:599-603. 2003....
Bone marrow and tumour stroma: an intimate relationshipNatalie C Direkze
Histopathology Unit, Cancer Research, UK
Hematol Oncol 24:189-95. 2006..This review focuses on the contribution of bone marrow cells to tumour stroma, highlighting the bone marrow as a potential new portal through which to direct anti-tumour therapies...
Stem cell plasticity and tumour formationMalcolm R Alison
Centre for Diabetes and Metabolic Medicine, Queen Mary School of Medicine and Dentistry, Institute of Cell and Molecular Science, 4 Newark Street, Whitechapel, London E1 2AT, UK
Eur J Cancer 42:1247-56. 2006..In the context of oncology, BMC derivation of the tumour stroma and vasculature has profound biological and therapeutic implications, and there are several examples of carcinomas seemingly being derived from BMCs...
