Research Topics
Genomes and GenesSpecies | Melody S ClarkSummaryAffiliation: British Antarctic Survey Country: UK Publications
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Detail Information
Publications
Antarctic krill 454 pyrosequencing reveals chaperone and stress transcriptomeMelody S Clark
British Antarctic Survey, Natural Environment Research Council, Cambridge, United Kingdom
PLoS ONE 6:e15919. 2011..Hence, understanding how this organism functions is a priority area and will provide fundamental data for life history studies, energy budget calculations and food web models...
Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratusFlorbela A Vieira
Comparative and Molecular Endocrinology Group, Centre for Marine Sciences CCMAR, Universidade do Algarve, Campus de Gambelas, 8005 139 Faro, Portugal
BMC Genomics 12:490. 2011....
Discovering genes associated with dormancy in the monogonont rotifer Brachionus plicatilisNadav Y Denekamp
Israel Oceanographic and Limnological Research, Haifa 31080, Israel
BMC Genomics 10:108. 2009..The aim of this study was to generate Expressed Sequence Tags (ESTs) for molecular characterisation of processes associated with the formation of resting eggs, their survival during dormancy and hatching...
Evolution of secretin family GPCR members in the metazoaJoão C R Cardoso
Centre of Marine Sciences, Universidade do Algarve, Campus de Gambelas, 8005 139 Faro, Portugal
BMC Evol Biol 6:108. 2006..In this study a comprehensive description of family 2 GPCR evolution is given based on in silico and expression analyses of the invertebrate receptor genes...
Persistence of duplicated PAC1 receptors in the teleost, Sparus auratusJoão C R Cardoso
CCMAR, Molecular and Comparative Endocrinology, University of Algarve, 8005 139 Faro, Portugal
BMC Evol Biol 7:221. 2007..These receptors belong to family 2 GPCRs and most of their members are duplicated in teleosts although the reason why both persist in the genome is unknown...
How insects survive the cold: molecular mechanisms-a reviewMelody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, UK
J Comp Physiol B 178:917-33. 2008....
Low heat-shock thresholds in wild Antarctic inter-tidal limpets (Nacella concinna)Melody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge, UK
Cell Stress Chaperones 13:51-8. 2008..However, experimental manipulation can provide molecular markers for identifying stress in Antarctic molluscs, provided it is accompanied by environmental validation, as demonstrated here...
Antarctic marine molluscs do have an HSP70 heat shock responseMelody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge, UK
Cell Stress Chaperones 13:39-49. 2008..This study shows that this is not the case for other Antarctic animals, with the two molluscs showing an inducible heat shock response, at a level probably set during their temperate evolutionary past...
Surviving extreme polar winters by desiccation: clues from Arctic springtail (Onychiurus arcticus) EST librariesMelody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge, CB3 0ET, UK
BMC Genomics 8:475. 2007..The aim of this project was to generate clones and sequence data in the form of ESTs to provide a platform for the future molecular characterisation of the processes involved in protective dehydration...
Characterisation of the warm acclimated protein gene (wap65) in the Antarctic plunderfish (Harpagifer antarcticus)Melody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, UK
DNA Seq 19:50-5. 2008..antarcticus...
Triggers of the HSP70 stress response: environmental responses and laboratory manipulation in an Antarctic marine invertebrate (Nacella concinna)Melody S Clark
Biological Sciences Division, British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, UK
Cell Stress Chaperones 14:649-60. 2009..These results provide intriguing clues not only to the complexity of HSP70 gene expression in response to environmental change but also insights into the stress response of a non-model species...
Surviving the cold: molecular analyses of insect cryoprotective dehydration in the Arctic springtail Megaphorura arctica (Tullberg)Melody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge, UK
BMC Genomics 10:328. 2009..There are no in-depth molecular studies on the underlying cold survival mechanisms in any species...
Fugu ESTs: new resources for transcription analysis and genome annotationMelody S Clark
MRC Rosalind Franklin Centre for Genomics Research, formerly known as the MRC UK HGMP Resource Centre, Genome Campus, Hinxton, Cambridge, CB10 1SB, UK
Genome Res 13:2747-53. 2003..This is particularly timely with the increasing availability of draft genome sequence from different organisms and the mounting emphasis on gene function and regulation...
Insights into shell deposition in the Antarctic bivalve Laternula elliptica: gene discovery in the mantle transcriptome using 454 pyrosequencingMelody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB30ET, UK
BMC Genomics 11:362. 2010..Hence, this species presents as an ideal candidate for studies into the processes of calcium regulation and shell deposition in our changing ocean environments...
Cold hardening processes in the Antarctic springtail, Cryptopygus antarcticus: clues from a microarrayJelena Purać
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, UK
J Insect Physiol 54:1356-62. 2008..These structural proteins mainly comprised cuticle proteins and provide support for the recent theory that summer SCP variation within Collembola species could be a consequence of moulting, with moulting population having lowered SCPs...
Genomic characterisation of putative growth hormone releasing hormone (GHRH) receptor genes in the teleost fish Fugu rubripesJoão C Cardoso
Fugu Genomics Group, MRC HGMP Resource Centre, Genome Campus, Hinxton, Cambridge, UK
DNA Seq 14:129-33. 2003..This is the first time that the genomic organisation of a GHRH receptor gene has been characterised from a nonmammalian vertebrate...
Fugu orthologues of human major histocompatibility complex genes: a genome surveyJennifer G Sambrook
Fugu Genomics, HGMP Resource Centre, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1SB, UK
Immunogenetics 54:367-80. 2002..Comparison with zebrafish substantiates previously observed linkages between class III region orthologues and hints at an ancient conserved class III region...
Long-term survival of hydrated resting eggs from Brachionus plicatilisMelody S Clark
British Antarctic Survey, Natural Environment Research Council, High Cross, Cambridge, United Kingdom
PLoS ONE 7:e29365. 2012....
Tolerance of Antarctic soil fungi to hydrocarbonsKevin A Hughes
British Antarctic Survey, Natural Environment Research Council, High Cross, Madingley Road, Cambridge CB3 0ET, United Kingdom
Sci Total Environ 372:539-48. 2007..Hyphal dry weight measurements suggested that Mortierella sp. may be able to use dodecane as sole carbon and energy source. Hydrocarbon-degrading Antarctic fungi may have use in future hydrocarbon spill bioremediation...
Characterisation, expression and promoter analysis of an interleukin 10 homologue in the puffer fish, Fugu rubripesJun Zou
Scottish Fish Immunology Research Centre, School of Biological Sciences, Zoology Building, University of Aberdeen, Aberdeen, AB24 2TZ, UK
Immunogenetics 55:325-35. 2003....
Whole-genome shotgun assembly and analysis of the genome of Fugu rubripesSamuel Aparicio
Institute of Molecular and Cell Biology, 30 Medical Drive, Singapore 117609
Science 297:1301-10. 2002..Conserved linkages between Fugu and human genes indicate the preservation of chromosomal segments from the common vertebrate ancestor, but with considerable scrambling of gene order...
Novel bioactive parathyroid hormone and related peptides in teleost fishAdelino V M Canario
Centro de Ciências do Mar do Algarve, Universidade do Algarve, Campus de Gambelas, 8005 139 Faro, Portugal
FEBS Lett 580:291-9. 2006..We hypothesise on the basis of phylogenetic and functional analysis that PTH-L could be a fish relic of an ancestral PTH/PTHrP gene...
Application of comparative genomics in fish endocrinologyDeborah M Power
CCMAR, Centre of Marine Sciences, Universidade do Algarve, Campus de Gambelas, 8000-810 Faro, Portugal
Int Rev Cytol 221:149-90. 2002....
Xena, a full-length basal retroelement from tetraodontid fishDamian E Dalle Nogare
Department of Biochemistry, University of Otago, Dunedin, New Zealand
Mol Biol Evol 19:247-55. 2002..The Penelope-Xena lineage is apparently a basal group within the retrotransposons and therefore represents an evolutionarily important class of retroelement...
