Research Topics
| D A KellySummaryAffiliation: Birmingham Heartlands Hospital Country: UK Publications
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Detail Information
Publications
Hepatitis C-Z: recent advancesD Kelly
Birmingham Children s Hospital and University of Birmingham, UK
Arch Dis Child 86:339-43. 2002..In this review, recently identified hepatitis viruses (hepatitis C, hepatitis D, hepatitis E, hepatitis F, hepatitis G, transfusion transmissible virus) are described, and the implications for paediatric liver disease discussed...
Viral hepatitis in childrenDeirdre Kelly
Liver Unit, Birmingham Children's Hospital, United Kingdom
Adv Exp Med Biol 549:83-90. 2004
Transplantation--new beginnings and new horizonsDeirdre Kelly
Liver Unit, Birmingham Children's Hospital, and Reader in Pediatric Hepatology, University of Birmingham, Birmingham Children's Hospital, United Kingdom
J Pediatr Gastroenterol Nutr 34:S51-3. 2002
Managing liver failureD A Kelly
Liver Unit, Birmingham Children s Hospital NHS Trust, UK
Postgrad Med J 78:660-7. 2002..Treatment includes specific medication, nutritional support, and liver transplantation, which now has a 90% survival with good quality life...
Isolated liver transplant in infants with short bowel syndrome: insights into outcomes and prognostic factorsD Dell-Olio
Liver Unit, Birmingham Children s Hospital BCH, Birmingham, UK
J Pediatr Gastroenterol Nutr 48:334-40. 2009..The aim of the study is to identify risk factors for unfavourable outcome in iLTx...
Current issues in the management of intestinal failureG L Gupte
Liver Unit, Birmingham Children s Hospital, Birmingham, UK
Arch Dis Child 91:259-64. 2006..Recent advances in small bowel transplantation and non-transplant surgical techniques now offer hope of sustained survival in the future without parenteral nutrition...
Is serum gentamicin level a good predictor of graft injury in intestinal transplantation?K S Haghighi
Liver Unit, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, United Kingdom
Transplant Proc 38:1733-4. 2006..Four of the five patients required laparotomies. CONCLUSION: We concluded that in our study raised serum gentamycin levels were a good predictor of rejection or significant injury to the graft...
Bile bilirubin pigment analysis in disorders of bilirubin metabolism in early infancyW S Lee
Liver Unit, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK
Arch Dis Child 85:38-42. 2001....
Immunosuppressive drugs in paediatric liver transplantationI D van Mourik
Liver Unit, The Birmingham Children s Hospital NHS Trust, England
Paediatr Drugs 3:43-60. 2001..Further development and research of efficacy and tolerability of existing drugs is, therefore, vital...
Induction therapy for small bowel transplant recipients: early experience in Birmingham, UKSue V Beath
Liver Unit at Birmingham Children's Hospital, Birmingham, West Midlands B4 6NH, United Kingdom
Transplant Proc 34:1892-3. 2002
Chronic hepatitis C in children--review of natural history at a National CentreM Abdel-Hady
Liver Unit, Birmingham Children s Hospital, Birmingham, UK
J Viral Hepat 18:e535-40. 2011..Consideration should be given to improve detection and diagnosis to refer children to specialist centres for management and antiviral therapy before developing fibrosis...
Current issues in pediatric transplantationD A Kelly
The Liver Unit, Birmingham Children s Hospital NHS Trust, Birmingham, UK
Pediatr Transplant 10:712-20. 2006....
Progress in treatment and outcome for children with neonatal haemochromatosisD M Flynn
Liver Unit, Birmingham Children s Hospital, Steelhouse Lane, Birmingham B4 6NH, UK
Arch Dis Child Fetal Neonatal Ed 88:F124-7. 2003..To evaluate the role of antioxidant treatment and liver transplantation in the management of neonatal haemochromatosis...
Neonatal liver transplantation for fulminant hepatitis caused by herpes simplex virus type 2W S Lee
Liver Units, Birmingham Children's Hospital, Birmingham, United Kingdom
J Pediatr Gastroenterol Nutr 35:220-3. 2002
Peripheral lymphocyte subsets in the management of PTLDG L Gupte
Liver Unit, Birmingham Children's Hospital, Steelhouse Lane, Birmingham B4 6NH, UK
Transplant Proc 34:1782-3. 2002
Cardiomyopathy in tyrosinaemia type I is common but usually benignN Arora
Liver Unit, Department of Cardiology, Children's Hospital NHS Trust, Birmingham, UK
J Inherit Metab Dis 29:54-7. 2006..CONCLUSION: Cardiomyopathy is a common manifestation of TTI and it has a favourable long-term outcome. Children initially treated with nitisinone are less likely to develop this complication...
Long-term challenges of immunosuppression in pediatric patientsD A Kelly
Liver Unit, Birmingham Children's Hospital NHS Trust, Birmingham, UK
Transplant Proc 37:1657-62. 2005
The frequency and outcome of biliary atresia in the UK and IrelandP J McKiernan
Liver Unit, Birmingham Children s Hospital NHS Trust, UK
Lancet 355:25-9. 2000..The outcome of a 2-year cohort of children with biliary atresia in the UK and Ireland was assessed to find the current frequency, the factors influencing outcome, and the medium-term need for liver transplantation...
Concomitant basiliximab with low-dose calcineurin inhibitors in children post-liver transplantationN Arora
Liver Unit, Birmingham Children's Hospital, Birmingham, UK
Pediatr Transplant 6:214-8. 2002..Further studies to evaluate the appropriate levels of CNI immunosuppression with Bx are required...
Population screening for neonatal liver disease: potential for a community-based programmeJ E Powell
Department of Public Health and Epidemiology, University of Birmingham, UK
J Med Screen 10:112-6. 2003..However, testing as part of the neonatal screening programme will prove practical only if the method can be adapted to use dried blood spots...
Tacrolimus and steroids versus ciclosporin microemulsion, steroids, and azathioprine in children undergoing liver transplantation: randomised European multicentre trialDeirdre Kelly
Liver Unit, Birmingham Children s Hospital NHS Trust, Birmingham, UK
Lancet 364:1054-61. 2004..We aimed to compare these drugs in children undergoing liver transplantation...
Current status of liver transplantationDeirdre Kelly
The Liver Unit, Birmingham Children's Hospital, Steelhouse Lane, Birmingham
Indian J Pediatr 70:731-6. 2003..Most children achieve good quality of life. There are still many lessons to learn and there are future challenges such as the ever increasing problems of donor scarcity and the search for potent but less toxic immunosuppressive agents...
Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study groupRobert H Squires
University of Pittsburgh, Children s Hospital of Pittsburgh, PA 15213, USA
J Pediatr 148:652-658. 2006..To determine short-term outcome for children with acute liver failure (ALF) as it relates to cause, clinical status, and patient demographics and to determine prognostic factors...
Chronic hepatitisKaren F Murray
Hepatobiliary Program, Seattle Children's Hospital and Regional Medical Center, Seattle, WA 98105, USA
J Pediatr Gastroenterol Nutr 47:225-33. 2008
Safety, efficacy, and pharmacokinetics of adefovir dipivoxil in children and adolescents (age 2 to <18 years) with chronic hepatitis BMaureen M Jonas
Children s Hospital Boston, Boston, MA 02115, USA
Hepatology 47:1863-71. 2008..CONCLUSION: ADV showed significant antiviral efficacy in subjects aged 12 to 17 years with HBeAg+ CHB, but was not different from placebo in subjects aged 2 to 11 years...
The pharmacokinetics and safety of adefovir dipivoxil in children and adolescents with chronic hepatitis B virus infectionEtienne M Sokal
Pediatric Research Institute, Departement de Pediatrie, Université Catholique de Louvain and Cliniques St Luc, 10 av Hippocrate, 1200 Brussels, Belgium
J Clin Pharmacol 48:512-7. 2008..There was 1 serious adverse event reported that was not related to study medication. No patient discontinued the study prematurely due to an adverse event related to the study drug...
A national sample of individuals who acquired hepatitis C virus infections in childhood or adolescence: risk factors for advanced diseaseHelen E Harris
Immunisation Department, Health Protection Agency, Centre for Infections, London, UK
J Pediatr Gastroenterol Nutr 45:335-41. 2007..To describe hepatitis C virus (HCV)-related liver disease in a national cohort of patients who acquired their infections in childhood or adolescence and to assess risk factors for progressive disease and response to antiviral therapy...
Visual loss and idiopathic intracranial hypertension in children with Alagille syndromePriya Narula
Liver Unit, Birmingham Children's Hospital, Birmingham, UK
J Pediatr Gastroenterol Nutr 43:348-52. 2006..CONCLUSIONS: We recommend annual fundoscopy in the follow-up of children with AGS to facilitate early detection and appropriate management of IIH to prevent visual loss...
Body growth after combined liver-kidney transplantation in children with primary hyperoxaluria type 1Richard Nissel
Department of Pediatric Nephrology, Charite Children s Hospital, Berlin, Germany
Transplantation 82:48-54. 2006..Combined liver and kidney transplantation (LKT) corrects the underlying metabolic defect and restores renal function in these children...
Viral hepatitis B and C in childrenDeirdre Kelly
The Liver Unit, Birmingham Children's Hospital, Birmingham B4 6NH, UK
J R Soc Med 99:353-7. 2006
Development of hepatopulmonary syndrome and portopulmonary hypertension in a paediatric liver transplant patientTahir Shah
University Hospital Birmingham and Birmingham Children s Hospital, Birmingham, UK
Pediatr Transplant 9:127-31. 2005..Although these syndromes are frequently diagnosed in patients undergoing assessment for liver transplantation, they seldom occur in the same patient...
