Research Topics
Species | Hakan BozcukSummaryAffiliation: Akdeniz University Country: Turkey Publications
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Detail Information
Publications
Correlates of benefit from neoadjuvant chemotherapy before radiotherapy in non-small cell lung cancer: a meta-analytical approach with meta-regression analysisH Bozcuk
Akdeniz University Medical Faculty, Department of Internal Medicine, Division of Medical Oncology, Antalya, Turkey
J BUON 15:43-50. 2010..In this setting, we assessed the predictors of benefit from neoadjuvant chemotherapy before radiotherapy...
Does awareness of diagnosis make any difference to quality of life? Determinants of emotional functioning in a group of cancer patients in TurkeyH Bozcuk
Akdeniz University School of Medicine, Department of Internal Medicine, Division of Medical Oncology, Antalya, Turkey
Support Care Cancer 10:51-7. 2002..On the contrary, those with hepatic dysfunction, female gender, poor social functioning and constipation are the ones at increased risk of poor emotional functioning, and these patients may benefit from psychological screening...
Fundamental principals of tumor necrosis factor-alpha gene therapy approach and implications for patients with lung carcinomaAhter D Sanlioglu
The Human Gene Therapy Unit, Faculty of Medicine, Akdeniz University Campus, B Block, 1st Floor, Antalya 07070, Turkey
Lung Cancer 44:199-211. 2004..Current progress in clinical trials using adenovirus-mediated delivery of TNF-alpha is also discussed...
Zoledronic acid is synergic with vinblastine to induce apoptosis in a multidrug resistance protein-1 dependent way: an in vitro studyMustafa Yildiz
Pamukkale University Medical Faculty, Department of Medical Oncology, Denizli, Turkey
Cell Biol Int 30:278-82. 2006..3%, P < 0.001). This preliminary work shows that zoledronic acid acts synergistically with vinblastine to induce apoptosis in an MRP-1 dependent way...
Does treatment delay affect survival in non-small cell lung cancer? A retrospective analysis from a single UK centreH Bozcuk
Oncology Division, Department of Internal Medicine, Akdeniz University Medical Faculty, Antalya 07070, Turkey
Lung Cancer 34:243-52. 2001....
A simple and accurate prediction model to estimate the intrahospital mortality risk of hospitalised cancer patientsH Bozcuk
Department of Medical Oncology, Akdeniz University Medical Faculty, Antalya, Turkey
Int J Clin Pract 58:1014-9. 2004..88 in the derivation cohort and 0.82 in the validation cohort. Using readily available clinical parameters, it is possible to devise an accurate and applicable risk prediction model for the hospitalised cancer patients...
Tumour necrosis factor-alpha, interleukin-6, and fasting serum insulin correlate with clinical outcome in metastatic breast cancer patients treated with chemotherapyHakan Bozcuk
Akdeniz University Medical Faculty, Department of Medical Oncology, Dumlupinar Bulvari, 07070 Antalya, Turkey
Cytokine 27:58-65. 2004..To assess the relationship of various growth factors and cytokines with the clinical outcome in metastatic breast cancer patients receiving chemotherapy...
Cluster analysis of p-glycoprotein, c-erb-B2 and P53 in relation to tumor histology strongly indicates prognosis in patients with operable non-small cell lung cancerHakan Bozcuk
Department of Medical Oncology, Faculty of Medicine, Akdeniz University, Antalya, Turkey
Med Sci Monit 11:HY11-20. 2005..We aimed to identify the roles of P53, c-erb- B2 and p-glycoprotein (pgp) as prognostic factors, independently or in conjunction with each other, in operable NSCLC...
Does music exposure during chemotherapy improve quality of life in early breast cancer patients? A pilot studyHakan Bozcuk
Akdeniz University Medical Faculty, Dept of Medical Oncology, Antalya, Turkey
Med Sci Monit 12:CR200-5. 2006..Adjuvant chemotherapy is associated with poor quality of life (qol) in breast cancer patients. We tested the effect of listening to music during chemotherapy on quality of life in these patients...
Quality of life in patients with advanced non-small cell lung cancerHakan Bozcuk
Department of Medical Oncology, Faculty of Medicine, Akdeniz University, Antalya, Turkey
Cancer Nurs 29:104-10. 2006..Conversely, in this cohort, patients who are likely to have deteriorating QOL on chemotherapy may benefit from closer follow-up and nursing care to optimize supportive measures...
The impact of waist-to-hip ratio on clinical outcomes in metastatic breast cancer patients treated with aromatase inhibitorsMehmet Artac
Division of Medical Oncology, Meram Medical Faculty, Selcuk University, Konya, Turkey
Breast 17:418-22. 2008..92 and >or=0.92 were 423 versus 1004 days (Log rank statistic=6.37, P=0.012). This study suggests that WHR may serve as a potential predictive marker in MBC patients treated with AIs...
Does maintenance/consolidation chemotherapy have a role in the management of small cell lung cancer (SCLC)? A metaanalysis of the published controlled trialsHakan Bozcuk
Akdeniz University Medical Faculty, Department of Internal Medicine, Division of Medical Oncology, Antalya, Turkey
Cancer 104:2650-7. 2005..The role of maintenance/consolidation chemotherapy was assessed in the management of small cell lung cancer (SCLC) via a metaanalytic approach...
The value of XPD and XRCC1 genotype polymorphisms to predict clinical outcome in metastatic colorectal carcinoma patients with irinotecan-based regimensMehmet Artac
Department of Medical Oncology, Meram Medical Faculty, Selcuk University, Meram, 42080 Konya, Turkey
J Cancer Res Clin Oncol 136:803-9. 2010..Previous studies have suggested that DNA repair enzyme polymorphisms may bear prognostic value in metastatic colorectal carcinoma (MCRC)...
Different clinical features of primary and secondary tumors in patients with multiple malignanciesMehmet Artac
Akdeniz University Medical School, Department of Internal Medicine, Division of Medical Oncology, Antalya, Turkey
Tumori 91:317-20. 2005..Thus, we recommend a long screening time for secondary tumors after a curative treatment in patients with common cancers, taking into account the different occurrence patterns of second primaries with respect to first primaries...
An application of a genetic algorithm in conjunction with other data mining methods for estimating outcome after hospitalization in cancer patientsHakan Bozcuk
Department of Medical Oncology, Akdeniz University Medical Faculty, Antalya 07070, Turkey
Med Sci Monit 10:CR246-51. 2004..We investigated which factors predicted the risk of in-hospital mortality in a general population of cancer patients with non-terminal disease and whether employing the genetic algorithm technique would be useful in this regard...
Low-grade inflammation in white-coat hypertensionMustafa Ozdogan
Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey
Med Sci Monit 13:CR570-3. 2007..The risk profile of white-coat hypertension is not yet completely clear. The aim of this study was to determine the levels of high-sensitivity CRP (hs-CRP) in white-coat hypertensive subjects...
Small cell carcinoma of the cervix: a case reportAylin Fidan Korcum
Department of Radiation Oncology, Akdeniz University, School of Medicine, 07070, Antalya, Turkey
Arch Gynecol Obstet 277:367-70. 2008..Subsequently, they were treated with pelvic external radiotherapy and high-dose-rate intracavitary brachytherapy with concurrent cisplatin based chemotherapy. They were alive with no evidence of disease at 91 and 65 months, respectively...
The value of CEA and CA 19-9 in detecting cancer in a group of high-risk subjects with gastrointestinal symptomsE Coban
Department of Internal Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey
Int J Biol Markers 18:177-81. 2003..In conclusion, in patients presenting with gastrointestinal complaints, the finding of elevated CEA levels may help in the diagnosis of cancer by prompting a more extensive search for intraabdominal cancer...
The value of low-dose intraperitoneal immunoglobulin administration in the treatment of peritoneal dialysis-related peritonitisErkan Coban
Department of Internal Medicine, Faculty of Medicine, Akdeniz University, Antalya, Turkey
J Nephrol 17:427-30. 2004..In this study, the effect of intraperitoneal (IP) immunoglobulin (Ig) usage, as an approach for strengthening opsonization, was evaluated in CAPD peritonitis...
Predictors of distant metastasis at presentation in breast cancer: a study also evaluating associations among common biological indicatorsH Bozcuk
Department of Internal Medicine, Akdeniz University Medical Faculty, Antalya, Turkey
Breast Cancer Res Treat 68:239-48. 2001..To investigate the correlation among some of the commonly used clinical, pathological factors and newer biological indicators, and to identify the independent predictors of distant metastasis at presentation in patients with breast cancer...
Cisplatin cytotoxicity is enhanced with zoledronic acid in A549 lung cancer cell line: preliminary results of an in vitro studyO H Ozturk
Akdeniz University, Department of Biochemistry, Antalya, Turkey
Cell Biol Int 31:1069-71. 2007..Thus, we show for the first time in a lung cancer cell line that zoledronic acid bears cytotoxic potential on its own and in conjunction with cisplatin. The clinical potential of this finding should be further studied...
The debate about maintenance is not over in small-cell lung cancerMehmet Artac
J Clin Oncol 25:5840; author reply 5840-1. 2007
