L Chouchane

Summary

Affiliation: Service de cardiologie
Country: Tunisie

Publications

  1. ncbi Associations between HLA class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians
    Xin Li
    Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    J Transl Med 5:22. 2007
  2. ncbi Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma
    Kaouther Snoussi
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Universite de Monastir, Tunisia
    BMC Cancer 6:38. 2006
  3. ncbi Implication of Xenobiotic Metabolizing Enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma
    Achraf Khedhaier
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Tunisia
    BMC Cancer 8:109. 2008
  4. ncbi A repeat polymorphism in interleukin-4 gene is highly associated with specific clinical phenotypes of asthma
    L Chouchane
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Monastir, Tunisia
    Int Arch Allergy Immunol 120:50-5. 1999
  5. ncbi Genetic variation in the stress protein hsp70-2 gene is highly associated with obesity
    L Chouchane
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Monastir, Tunisia
    Int J Obes Relat Metab Disord 25:462-6. 2001
  6. ncbi Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: susceptibility and prognostic implications in breast carcinoma
    A Khedhaier
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, 5019 Monastir, Tunisia
    Br J Cancer 89:1502-7. 2003
  7. ncbi NS5A(ISDR-V3) region genetic variability of Tunisian HCV-1b strains: Correlation with the response to the combined interferon/ribavirin therapy
    N Bouzgarrou
    Molecular Immuno oncology Laboratory, Faculty of Medicine, Monastir, Tunisia
    J Med Virol 81:2021-8. 2009
  8. ncbi Interleukin-10 and interferon-gamma gene polymorphisms in patients with nasopharyngeal carcinoma
    K Farhat
    Laboratory of Molecular Immuno Oncology, Faculty of Medicine of Monastir, Monastir, Tunisia
    Int J Immunogenet 35:197-205. 2008
  9. ncbi Dimorphism of TAP-1 gene in Caucasian with juvenile myoclonic epilepsy and in Tunisian with idiopathic generalized epilepsies
    S Layouni
    Department of Physiology, Faculty of Medicine, Monastir, Tunisia
    Int J Immunogenet 37:117-23. 2010
  10. ncbi Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma
    S Mestiri
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Université du Centre, 5019 Monastir, Tunisia
    Cancer 91:672-8. 2001

Collaborators

  • E Schvoerer
  • S B Ahmed
  • B Hamrita
  • I Sfar
  • A Ismail
  • M Corbex
  • A Malafosse
  • O Bahri
  • A Meddeb-Garnaoui
  • E Hassen
  • S Gabbouj
  • N Bouzgarrou
  • K Zouari Bouassida
  • W Mahfoudh
  • Noureddine Bouaouina
  • N Bouaouina
  • S Layouni
  • S Remadi
  • H Triki
  • A Khedhaier
  • S Sfar
  • Achraf Khedhaier
  • K Farhat
  • S Mestiri
  • Xin Li
  • Kaouther Snoussi
  • S Cherif
  • S Haddad
  • J Danguir
  • K Jellouli
  • M Dogui
  • A Ben Yahia
  • N Ben Mami
  • N Mammi
  • N Maamouri
  • H Saffar
  • Elham Hassen
  • A Trabelsi
  • F Stoll-Keller
  • Sallouha Gabbouj
  • I Cheikh
  • A Romdhane
  • Nahla Ghandri
  • Silvia Selleri
  • Ena Wang
  • Domenico Adorno
  • Sharon Adams
  • Francesco M Marincola
  • Alessandro Monaco
  • Fu Meei Robbins
  • B Bel Hadj Jrad
  • David Stroncek
  • Daniela Piancatelli
  • Deborah Chen
  • A Noureddine Helal
  • Slim Ben Ahmed
  • A Donny Strosberg
  • H Khairi
  • J P Briand
  • J Hoebeke
  • A Zakhama
  • R Kacem
  • A Chaieb
  • R Azaiez
  • A N Helal
  • B B Jrad

Detail Information

Publications18

  1. ncbi Associations between HLA class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians
    Xin Li
    Immunogenetics Section, Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    J Transl Med 5:22. 2007
    ..In addition, we identified a putative haplotype rare in Tunisian patients with NPC that may serve as a genetic marker for further susceptibility studies...
  2. ncbi Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma
    Kaouther Snoussi
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Universite de Monastir, Tunisia
    BMC Cancer 6:38. 2006
    ..Leptin exerts its physiological action through its specific receptor (LEPR). We have investigated whether genetic variations in LEP and LEPR have implications for susceptibility to and prognosis in breast carcinoma...
  3. ncbi Implication of Xenobiotic Metabolizing Enzyme gene (CYP2E1, CYP2C19, CYP2D6, mEH and NAT2) polymorphisms in breast carcinoma
    Achraf Khedhaier
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Tunisia
    BMC Cancer 8:109. 2008
    ..This study investigated the susceptibility and prognostic implications of the CYP2E1, CYP2C19, CYP2D6, mEH and NAT2 gene polymorphisms in breast carcinoma patients...
  4. ncbi A repeat polymorphism in interleukin-4 gene is highly associated with specific clinical phenotypes of asthma
    L Chouchane
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Monastir, Tunisia
    Int Arch Allergy Immunol 120:50-5. 1999
    ..The authors designed a case-controlled study to investigate the potential association of a repeat polymorphism in IL-4 gene with specific clinical phenotypes of asthma...
  5. ncbi Genetic variation in the stress protein hsp70-2 gene is highly associated with obesity
    L Chouchane
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Monastir, Tunisia
    Int J Obes Relat Metab Disord 25:462-6. 2001
    ..We designed a case-controlled study to investigate the potential association of polymorphism of the TNF-alpha and that of a stress protein (hsp70-2) with obesity...
  6. ncbi Glutathione S-transferases (GSTT1 and GSTM1) gene deletions in Tunisians: susceptibility and prognostic implications in breast carcinoma
    A Khedhaier
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, 5019 Monastir, Tunisia
    Br J Cancer 89:1502-7. 2003
    ..The gene deletion of GSTs may predict not only the early onset of breast carcinoma but also the clinical response to chemotherapy and the recurrence-free survival for patients with lymph node-negative breast carcinoma...
  7. ncbi NS5A(ISDR-V3) region genetic variability of Tunisian HCV-1b strains: Correlation with the response to the combined interferon/ribavirin therapy
    N Bouzgarrou
    Molecular Immuno oncology Laboratory, Faculty of Medicine, Monastir, Tunisia
    J Med Virol 81:2021-8. 2009
    ..The genetic variability within the NS5A region of HCV-1b strains was associated with the response to the combined IFN plus ribavirin therapy in our Tunisian cohort...
  8. ncbi Interleukin-10 and interferon-gamma gene polymorphisms in patients with nasopharyngeal carcinoma
    K Farhat
    Laboratory of Molecular Immuno Oncology, Faculty of Medicine of Monastir, Monastir, Tunisia
    Int J Immunogenet 35:197-205. 2008
    ..Nevertheless, we strongly believe that the relationship between cytokines polymorphisms and NPC susceptibility deeply depends on the ethnicity...
  9. ncbi Dimorphism of TAP-1 gene in Caucasian with juvenile myoclonic epilepsy and in Tunisian with idiopathic generalized epilepsies
    S Layouni
    Department of Physiology, Faculty of Medicine, Monastir, Tunisia
    Int J Immunogenet 37:117-23. 2010
    ..In this study, we report an association between two TAP-1 functional polymorphisms the I333V and the D637G and most common IGE in Tunisian population, but we fail to find significant results in Caucasian with JME...
  10. ncbi Genetic variation in the tumor necrosis factor-alpha promoter region and in the stress protein hsp70-2: susceptibility and prognostic implications in breast carcinoma
    S Mestiri
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Université du Centre, 5019 Monastir, Tunisia
    Cancer 91:672-8. 2001
    ..The authors designated a large study to investigate the susceptibility and prognostic implications of the genetic variation in TNF-alpha and hsp70-2 in breast carcinoma...
  11. ncbi A polymorphism in FAS gene promoter correlated with circulating soluble FAS levels
    W Mahfoudh
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Universite de Monastir, Tunisia
    Int J Immunogenet 34:209-12. 2007
    ..90 ng mL(-1) vs. 3.12 ng mL(-1), P = 0.035). Our results demonstrated that FAS promoter polymorphism was significantly associated with the level of soluble FAS production in normal subjects...
  12. ncbi Association of interleukin-18 polymorphisms and plasma level with the outcome of chronic HCV infection
    N Bouzgarrou
    Laboratory of Molecular Immuno Oncology, Faculty of Medicine, Monastir, Tunisia
    J Med Virol 80:607-14. 2008
    ..0001) that correlate with disease severity (P = 0.01, P = 0.001, P = 0.0006, respectively). In conclusion, we supposed a possible implication of IL-18 promoter polymorphisms in the pathogenesis of chronic HCV infection...
  13. ncbi [Human genome project: a federator program of genomic medicine]
    S Sfar
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, Avenue Avicenne, Monastir, Tunisia
    Pathol Biol (Paris) 56:170-5. 2008
    ..The pharmacogenomics could give rise to a new generation of highly effective drugs that treat causes, not just symptoms...
  14. ncbi [The therapeutic contribution of proteomic approaches in cancers]
    B Hamrita
    Laboratoire d Immuno Oncologie Moleculaire, Faculte de medecine de Monastir, 5019 Monastir, Tunisie
    Gynecol Obstet Fertil 39:87-93. 2011
    ..The purpose of the current review is to describe the major advances in cancer proteomics, especially those related to the study of serum biomarkers, immune-related responses (autoantibodies) and alterations in cellular proteins...
  15. ncbi Association analysis of HLA-class II and class III gene polymorphisms in the susceptibility to mediterranean visceral leishmaniasis
    A Meddeb-Garnaoui
    Laboratory of Immunology, Institut Pasteur de Tunis, Tunis Belvedere, Tunisia
    Hum Immunol 62:509-17. 2001
    ..94; p = 0.04). Again, this result was not significant after using Bonferroni correction. These results do not support association between susceptibility to MVL and the MHC class II and class III loci analyzed in this study...
  16. ncbi Polymorphism of stress protein HSP70-2 gene in Tunisians: susceptibility implications in type 2 diabetes and obesity
    K Zouari Bouassida
    Service de Nutrition expérimentale, Institut de Nutrition, Tunis, Tunisie
    Diabetes Metab 30:175-80. 2004
    ..We designated a case-controlled study to investigate a potential association of genetic variation of the TNFalpha and that of the heat shock protein 70-2 (HSP70-2) with type 2 diabetes...
  17. ncbi Cervical cancer and HPV
    E Hassen
    Laboratoire d'Immunologie,
    Tunis Med 83:61. 2005
  18. ncbi The peroxisome proliferator activated receptorgamma2 (PPARgamma2) Pro12Ala variant: lack of association with type 2 diabetes in obese and non obese Tunisian patients
    K Zouari Bouassida
    Service of Experimental Nutrition, Institute of Nutrition, Tunis, Tunisia
    Diabetes Metab 31:119-23. 2005
    ..We designed a case-controlled study to investigate the potential association of the genetic variation of the PPARgamma2 gene with type 2 diabetes in Tunisians...