Using a business model approach and marketing techniques for recruitment to clinical trialsAlison M McDonald
Health Services Research Unit, University of Aberdeen, Health Sciences Building, Foresterhill, Aberdeen AB252ZD, UK
Trials 12:74. 2011
..We review what is known about interventions to improve recruitment to trials. We describe a proposed business approach to trials and discuss the implementation of using a business model, using insights gained from three case studies...
- Development of a theory of implementation and integration: Normalization Process Theory
Carl R May
Institute of Health and Society, Newcastle University, Newcastle, UK
Implement Sci 4:29. 2009
..CONCLUSION: Normalization Process Theory has been developed through procedures that were properly sceptical and critical, and which were opened to review at each stage of development. The theory has been shown to merit formal testing...
- Study protocol for BeWEL: the impact of a BodyWEight and physicaL activity intervention on adults at risk of developing colorectal adenomas
Angela M Craigie
Centre for Research into Cancer Prevention and Screening, University of Dundee, UK
BMC Public Health 11:184. 2011
..These diseases share risk factors related to the metabolic syndrome including large body size, abnormal lipids and markers of insulin resistance indicating common aetiological pathways...
- Normalisation process theory: a framework for developing, evaluating and implementing complex interventions
Elizabeth Murray
Research Department of Primary Care and Population Health, University College London, Upper Floor 3, Royal Free Hospital, Rowland Hill Street, London NW3 2PF, UK
BMC Med 8:63. 2010
..The Normalisation Process Theory (NPT) addresses the factors needed for successful implementation and integration of interventions into routine work (normalisation)...
- Evaluating complex interventions and health technologies using normalization process theory: development of a simplified approach and web-enabled toolkit
Carl R May
Faculty of Health Sciences, University of Southampton, UK
BMC Health Serv Res 11:245. 2011
..This paper describes the processes by which we developed a simplified version of NPT for use by clinicians, managers, and policy makers, and which could be embedded in a web-enabled toolkit and on-line users manual...
- Understanding the implementation of complex interventions in health care: the normalization process model
Carl May
Institute of Health and Society, Newcastle University, 21 Claremont Place, Newcastle upon Tyne, NE2 4AA, UK
BMC Health Serv Res 7:148. 2007
..It offers a framework for process evaluation and also for comparative studies of complex interventions. It focuses on the factors that promote or inhibit the routine embedding of complex interventions in health care practice...
- Making trials matter: pragmatic and explanatory trials and the problem of applicability
Shaun Treweek
Division of Clinical and Population Sciences and Education, University of Dundee, Dundee, UK
Trials 10:37. 2009
..If we want evidence from trials to be used in clinical practice and policy, trialists should make every effort to make their trial widely applicable, which means that more trials should be pragmatic in attitude...
- Incomplete reporting of recruitment information in breast cancer trials published between 2003 and 2008
Shaun Treweek
Quality, Safety and Informatics Research Group, University of Dundee, Kirsty Semple Way, Dundee DD2 4BF, UK
J Clin Epidemiol 64:1216-22. 2011
..To review the reporting of key items of recruitment information in trial reports and estimate the number needed to screen to recruit one additional participant...
- Developing and evaluating interventions to reduce inappropriate prescribing by general practitioners of antibiotics for upper respiratory tract infections: A randomised controlled trial to compare paper-based and web-based modelling experiments
Shaun Treweek
Quality, Safety and Informatics Research Group, University of Dundee, Kirsty Semple Way, Dundee, UK
Implement Sci 6:16. 2011
..They do this by delivering key elements of the intervention in a simulation that approximates clinical practice by, for example, presenting general practitioners (GPs) with a clinical scenario about making a treatment decision...
- Desktop software to identify patients eligible for recruitment into a clinical trial: using SARMA to recruit to the ROAD feasibility trial
Shaun Treweek
Clinical and Population Sciences and Education, University of Dundee, Dundee, UK
Inform Prim Care 18:51-8. 2010
..For patients willing to learn more about the trial, the software allows practice staff to send the patient's contact details to the research team by text message...
- How much does pre-trial testing influence complex intervention trials and would more testing make any difference? An email survey
Shaun Treweek
Tayside Centre for General Practice, Community Health Sciences Division, University of Dundee, Kirsty Semple Way, Dundee DD2 4BF, UK
BMC Med Res Methodol 6:28. 2006
..This study aimed to determine to what extent complex interventions are tested prior to a full-scale trial and whether more or different testing would have led to a different intervention being used in the trial...
- Strategies to improve recruitment to randomised controlled trials
Shaun Treweek
Division of Clinical and Population Sciences and Education, University of Dundee, Kirsty Semple Way, Dundee, UK, DD2 4BF
Cochrane Database Syst Rev 4:MR000013. 2010
..Some strategies (e.g. open trial designs) need to be considered carefully before use because they also have disadvantages. For example, opt-out procedures are controversial and open designs are by definition unblinded...
- The Trial Protocol Tool: The PRACTIHC software tool that supported the writing of protocols for pragmatic randomized controlled trials
Shaun Treweek
Tayside Centre for General Practice, University of Dundee, DD2 4BF Dundee, UK
J Clin Epidemiol 59:1127-33. 2006
..To develop a tool that would make it easier for researchers, especially those in low- and middle-income countries, to write research protocols for pragmatic randomized controlled trials...
- Public attitudes to the storage of blood left over from routine general practice tests and its use in research
Shaun Treweek
Tayside Centre for General Practice, Division of Clinical and Population Sciences and Education, University of Dundee, Dundee, UK
J Health Serv Res Policy 14:13-9. 2009
..To this end, our study aimed to investigate the attitudes of members of the public recruited through general practices to the donation and storage of blood left over from routine clinical tests in general practice...
- Complex interventions and the chamber of secrets: understanding why they work and why they do not
Shaun Treweek
Tayside Centre for General Practice, University of Dundee, Kirsty Semple Way, Dundee DD2 4BF, Scotland, UK
J R Soc Med 98:553. 2005
