The timing of surgical antimicrobial prophylaxisWalter P Weber
Department of General Surgery, University Hospital of Basel, Basel, Switzerland
Ann Surg 247:918-26. 2008
..To obtain precise information on the optimal time window for surgical antimicrobial prophylaxis...
- Clinical review: Severe malaria
Andrej Trampuz
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Crit Care 7:315-23. 2003
..For early diagnosis, it is paramount to consider malaria in every febrile patient with a history of travel in an area endemic for malaria...
- Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults: a retrospective analysis over an 11-year period
Anna Conen
Division of Infectious Diseases and Hospital Epidemiology, Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
Clin Infect Dis 47:73-82. 2008
..Data on infections associated with cerebrospinal fluid (CSF) shunts among adults are limited. Therefore, we performed a retrospective study of shunt-associated infections in adults...
- Avian influenza: a new pandemic threat?
Andrej Trampuz
Division of Infectious Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:523-30; quiz 530. 2004
..This article summarizes the current knowledge on avian influenza, including the virology, epidemiology, diagnosis, and management of this emerging disease...
- Changes in the epidemiology of pneumococcal bacteremia in a Swiss university hospital during a 15-year period, 1986-2000
Andrej Trampuz
Division of Infectious Diseases, Department of Internal Medicine, University Hospitals, Basel, Switzerland
Mayo Clin Proc 79:604-12. 2004
..To evaluate changes in epidemiological characteristics and outcome of patients with pneumococcal bacteremia during a 15-year period in a Swiss university hospital...
- In vitro activity of gallium maltolate against Staphylococci in logarithmic, stationary, and biofilm growth phases: comparison of conventional and calorimetric susceptibility testing methods
Daniela Baldoni
Infectious Diseases, Department of Biomedicine, University Hospital, Basel, Switzerland
Antimicrob Agents Chemother 54:157-63. 2010
..These data support the potential topical use of GaM, including its use for the treatment of wound infections, MRSA decolonization, and coating of implants...
- Linezolid alone or combined with rifampin against methicillin-resistant Staphylococcus aureus in experimental foreign-body infection
Daniela Baldoni
Department of Biomedicine, Infectious Diseases Research Laboratory, University Hospital Basel, Basel, Switzerland
Antimicrob Agents Chemother 53:1142-8. 2009
..The linezolid-rifampin combination is a treatment option for implant-associated infections caused by quinolone-resistant MRSA...
- Sonication of removed hip and knee prostheses for diagnosis of infection
Andrej Trampuz
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
N Engl J Med 357:654-63. 2007
..We hypothesized that culturing of samples obtained from the prosthesis would improve the microbiologic diagnosis of prosthetic-joint infection...
- Efficacy of daptomycin in implant-associated infection due to methicillin-resistant Staphylococcus aureus: importance of combination with rifampin
Anne Kathrin John
Infectious Diseases Service, Department of Internal Medicine, University Hospital and University of Lausanne, Rue du Bugnon 46, Lausanne, Switzerland
Antimicrob Agents Chemother 53:2719-24. 2009
..Daptomycin plus rifampin is a promising treatment option for implant-associated MRSA infections...
- Lack of association of Staphylococcus aureus type A beta-lactamase with cefazolin combined with antimicrobial spacer placement prosthetic joint infection treatment failure
Jennifer A Shuford
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Diagn Microbiol Infect Dis 54:189-92. 2006
..We conclude that type A blaZ is common in MSSA PJI and that cefazolin therapy for blaZ MSSA PJI can be successful when combined with 2-stage reimplantation and local antimicrobial therapy...
- Efficacy of a novel rifamycin derivative, ABI-0043, against Staphylococcus aureus in an experimental model of foreign-body infection
Andrej Trampuz
Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
Antimicrob Agents Chemother 51:2540-5. 2007
..ABI-0043 in combination with a quinolone has the potential for treatment of implant-associated infections caused by susceptible strains of S. aureus, potentially without drug-drug interactions...
- High rate of aminoglycoside resistance among staphylococci causing prosthetic joint infection
Paloma Anguita-Alonso
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Clin Orthop Relat Res 439:43-7. 2005
..The findings suggest that consideration should be given to the further study of agents other than aminoglycosides for incorporation into polymethylmethacrylate for the treatment and prevention of prosthetic joint infection...
- Performance of microcalorimetry for early detection of methicillin resistance in clinical isolates of Staphylococcus aureus
Daniela Baldoni
Infectious Diseases Research Laboratory, Department of Biomedicine, University Hospital, Basel, Switzerland
J Clin Microbiol 47:774-6. 2009
..Among 30 genetically distinct clinical isolates, 19/20 MRSA (95%) and 10/10 methicillin-susceptible Staphylococcus aureus (100%) were correctly identified. Microcalorimetry may be useful for rapid MRSA screening...
- Sonication of explanted prosthetic components in bags for diagnosis of prosthetic joint infection is associated with risk of contamination
Andrej Trampuz
Division of Infectious Diseases, Mayo Clinic College of Medicine, 200 First St. S.W, Rochester, MN 55905, USA
J Clin Microbiol 44:628-31. 2006
..Sonication in bags improved bacterial recovery from the surface of orthopedic implants; however, it lacked specificity, due to bag leakage...
- Improved diagnosis of periprosthetic joint infection by multiplex PCR of sonication fluid from removed implants
Yvonne Achermann
Infectious Diseases Service, Department of Internal Medicine, Cantonal Hospital Zug, Baar, Switzerland
J Clin Microbiol 48:1208-14. 2010
..With modified primer sets, multiplex PCR has the potential for further improvement of the diagnosis of PJI...
- Effect of gamma irradiation on viability and DNA of Staphylococcus epidermidis and Escherichia coli
Andrej Trampuz
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Med Microbiol 55:1271-5. 2006
..This finding has practical implications for those using molecular diagnostic techniques in microbiology...
- Infections associated with orthopedic implants
Andrej Trampuz
Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
Curr Opin Infect Dis 19:349-56. 2006
..The treatment modality depends on duration of infection, stability of the implant, antimicrobial susceptibility of the pathogen and condition of the surrounding soft tissue...
- The value of serum procalcitonin level for differentiation of infectious from noninfectious causes of fever after orthopaedic surgery
Sabina Hunziker
Department of Internal Medicine, University Hospital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
J Bone Joint Surg Am 92:138-48. 2010
..There are currently no reliable diagnostic markers to differentiate infectious from noninfectious causes of postoperative fever. We investigated the value of the serum procalcitonin level in febrile patients after orthopaedic surgery...
- Antimicrobial agents in orthopaedic surgery: Prophylaxis and treatment
Andrej Trampuz
Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
Drugs 66:1089-105. 2006
..Vaccination against Staphylococcus aureus with StaphVAX induced specific antibodies potentially preventing bacteraemia; however, there are no studies on efficacy in the prophylaxis of device-associated infections with this vaccine...
- Prosthetic joint infections: update in diagnosis and treatment
Andrej Trampuz
Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Basel, Switzerland
Swiss Med Wkly 135:243-51. 2005
..In this article, epidemiology, pathogenesis, diagnosis and treatment of prosthetic joint infections are reviewed...
- Improved detection of microbial ureteral stent colonisation by sonication
Gernot Bonkat
Department of Urology, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland
World J Urol 29:133-8. 2011
..The aim of the present study was to evaluate the potential of sonication in the detection of MUSC and to identify risk factors for device colonisation...
- Phenotypic and genotypic mupirocin resistance among Staphylococci causing prosthetic joint infection
Margalida Rotger
Division of Infectious Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First St. SW, Rochester, MN 55905, USA
J Clin Microbiol 43:4266-8. 2005
..mupA was detected in all five high-level mupirocin-resistant staphylococci and one mupirocin-susceptible staphylococcus...
- Hand hygiene: a frequently missed lifesaving opportunity during patient care
Andrej Trampuz
Division of Infectious Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:109-16. 2004
..Reducing health care-associated infections requires that health care workers take responsibility for ensuring that hand hygiene becomes an everyday part of patient care...
- Clinical predictors for Legionella in patients presenting with community-acquired pneumonia to the emergency department
Rico Fiumefreddo
Department of Internal Medicine, Kantonsspital Aarau, Tellstrasse, CH 5001 Aarau, Switzerland
BMC Pulm Med 9:4. 2009
..Accurate clinical predictors to assess the likelihood of Legionella community-acquired pneumonia (CAP) in patients presenting to the emergency department are lacking...
- A high-mobility, low-cost phenotype defines human effector-memory CD8+ T cells
Gabriela Zenhaeusern
Immunobiology Laboratory, Department of Biomedicine, University Hospital Basel, 20 Hebelstrasse, Basel, Switzerland
Blood 113:95-9. 2009
..Together these assays indicated a high energy efficiency of the high crawling frequency CD8+ T-cell population, and identified differentially regulated heat production among nonlymphoid versus lymphoid homing CD8+ T cells...
- Persistent ulcers on the hand of an aquarium owner
Andrej Trampuz
Department of Internal Medicine, University Hospitals, Basel, Switzerland
Scand J Infect Dis 34:630-2. 2002
..Indeed, reassessment of histopathology revealed acid-fast bacilli, and mycobacterial cultures at 30 degrees C grew Mycobacterium marinum. Eventually, surgical reconstruction of the tendons was needed...
- Pharmacokinetics and pharmacodynamics of gatifloxacin against Streptococcus pneumoniae and Staphylococcus aureus in a granulocyte-rich exudate
Andrej Trampuz
Division of Infectious Diseases, Departments of Internal Medicine and Research, University Hospitals, Basel, Switzerland
Antimicrob Agents Chemother 46:3630-3. 2002
..Five hours after a single dose of gatifloxacin, SBF killed 2.5 logs of Streptococcus pneumoniae and 1.5 log of Staphylococcus aureus during a 2-h incubation ex vivo...
- TB in a low-incidence country: differences between new immigrants, foreign-born residents and native residents
Gerd Laifer
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland
Am J Med 120:350-6. 2007
..Active screening programs are likely to change the clinical presentation of TB, but the extent of the difference between immigrant and resident populations has not been studied prospectively...
