Margreet R Olthof

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. ncbi Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans
    Margreet R Olthof
    Division of Human Nutrition and Epidemiology, Wageningen University, Wageningen, The Netherlands
    J Nutr 133:1806-14. 2003
  2. ncbi Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women
    Margreet R Olthof
    Wageningen Centre for Food Sciences and Wageningen University, Division of Human Nutrition and Epidemiology, Wageningen, The Netherlands
    J Nutr 133:4135-8. 2003
  3. ncbi Effects of betaine intake on plasma homocysteine concentrations and consequences for health
    M R Olthof
    Wageningen Centre for Food Sciences and Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
    Curr Drug Metab 6:15-22. 2005
  4. ncbi Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans
    Margreet R Olthof
    Wageningen Centre for Food Sciences, Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    PLoS Med 2:e135. 2005
  5. ncbi Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men
    Margreet R Olthof
    Wageningen Centre for Food Sciences and the Division of Human Nutrition, Wageningen University, Wageningen, Netherlands Quality of Life, Zeist, Netherlands
    Am J Clin Nutr 82:111-7. 2005
  6. ncbi A high-protein diet increases postprandial but not fasting plasma total homocysteine concentrations: a dietary controlled, crossover trial in healthy volunteers
    Petra Verhoef
    Nutrition and Health Programme, Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am J Clin Nutr 82:553-8. 2005
  7. ncbi Dietary serine and cystine attenuate the homocysteine-raising effect of dietary methionine: a randomized crossover trial in humans
    Petra Verhoef
    Wageningen Centre for Food Sciences, Nutrition and Health Programme, Wageningen, Netherlands
    Am J Clin Nutr 80:674-9. 2004
  8. ncbi Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women
    G W Dalmeijer
    Wageningen University, Wageningen, The Netherlands
    Eur J Clin Nutr 62:386-94. 2008
  9. ncbi Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans
    M R Olthof
    Division of Human Nutrition and Epidemiology, Wageningen University, Wageningen, Netherlands
    Am J Clin Nutr 73:532-8. 2001

Collaborators

Detail Information

Publications9

  1. ncbi Chlorogenic acid, quercetin-3-rutinoside and black tea phenols are extensively metabolized in humans
    Margreet R Olthof
    Division of Human Nutrition and Epidemiology, Wageningen University, Wageningen, The Netherlands
    J Nutr 133:1806-14. 2003
    ..Metabolites of dietary phenols have lower antioxidant activity than their parent compounds; therefore, the contribution of dietary phenols to antioxidant activity in vivo might be lower than expected from in vitro tests...
  2. ncbi Low dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women
    Margreet R Olthof
    Wageningen Centre for Food Sciences and Wageningen University, Division of Human Nutrition and Epidemiology, Wageningen, The Netherlands
    J Nutr 133:4135-8. 2003
    ..0002) less, respectively. Thus, doses of betaine in the range of dietary intake reduce fasting and postmethionine loading plasma homocysteine concentrations. A betaine-rich diet might therefore lower cardiovascular disease risk...
  3. ncbi Effects of betaine intake on plasma homocysteine concentrations and consequences for health
    M R Olthof
    Wageningen Centre for Food Sciences and Wageningen University, Division of Human Nutrition, Wageningen, The Netherlands
    Curr Drug Metab 6:15-22. 2005
    ..However, whether the potential beneficial health effects of betaine and choline outweigh the possible adverse effects on serum lipids is as yet unclear...
  4. ncbi Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans
    Margreet R Olthof
    Wageningen Centre for Food Sciences, Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands
    PLoS Med 2:e135. 2005
    ..We therefore investigated the effect of betaine, of its precursor choline in the form of phosphatidylcholine, and of the classical homocysteine-lowering vitamin folic acid on blood lipid concentrations in healthy humans...
  5. ncbi Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men
    Margreet R Olthof
    Wageningen Centre for Food Sciences and the Division of Human Nutrition, Wageningen University, Wageningen, Netherlands Quality of Life, Zeist, Netherlands
    Am J Clin Nutr 82:111-7. 2005
    ..Choline is the precursor for betaine, but the effects of choline supplementation on plasma total homocysteine (tHcy) concentrations in healthy humans are unknown...
  6. ncbi A high-protein diet increases postprandial but not fasting plasma total homocysteine concentrations: a dietary controlled, crossover trial in healthy volunteers
    Petra Verhoef
    Nutrition and Health Programme, Wageningen Centre for Food Sciences, Wageningen, The Netherlands
    Am J Clin Nutr 82:553-8. 2005
    ..A high protein intake and hence a high intake of methionine--the sole dietary precursor of homocysteine--may raise plasma tHcy concentrations...
  7. ncbi Dietary serine and cystine attenuate the homocysteine-raising effect of dietary methionine: a randomized crossover trial in humans
    Petra Verhoef
    Wageningen Centre for Food Sciences, Nutrition and Health Programme, Wageningen, Netherlands
    Am J Clin Nutr 80:674-9. 2004
    ..The increase in tHcy induced by methionine, the sole dietary precursor of homocysteine, might be modulated by other amino acids present in dietary proteins...
  8. ncbi Prospective study on dietary intakes of folate, betaine, and choline and cardiovascular disease risk in women
    G W Dalmeijer
    Wageningen University, Wageningen, The Netherlands
    Eur J Clin Nutr 62:386-94. 2008
    ..To investigate the association between dietary intakes of folate, betaine and choline and the risk of cardiovascular disease (CVD)...
  9. ncbi Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans
    M R Olthof
    Division of Human Nutrition and Epidemiology, Wageningen University, Wageningen, Netherlands
    Am J Clin Nutr 73:532-8. 2001
    ..Chlorogenic acid is a major polyphenol in coffee; coffee drinkers consume up to 1 g chlorogenic acid/d...