Research Topics
Genomes and GenesSpecies | Joost J B KeurentjesSummaryAffiliation: Wageningen University Country: The Netherlands Publications
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Detail Information
Publications
Regulatory network construction in Arabidopsis by using genome-wide gene expression quantitative trait lociJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Arboretumlaan 4, NL 6703 BD Wageningen, The Netherlands
Proc Natl Acad Sci U S A 104:1708-13. 2007..Results that revealed clusters of coregulated genes and their most likely regulators were in agreement with published data, and unknown relationships could be predicted...
The genetics of plant metabolismJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Arboretumlaan 4, NL-6703 BD Wageningen, The Netherlands
Nat Genet 38:842-9. 2006..More than one-third of the signals were not detected in either parent, indicating the large potential for modification of metabolic composition through classical breeding...
Genetical metabolomics: closing in on phenotypesJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Arboretumlaan 4, NL 6703 BD Wageningen, The Netherlands
Curr Opin Plant Biol 12:223-30. 2009..It is now clear that modern plant sciences can benefit enormously from integrated multidisciplinary approaches...
Redefining plant systems biology: from cell to ecosystemJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands
Trends Plant Sci 16:183-90. 2011..The coupling of aggregation levels in plant sciences, termed Integral Quantification of Biological Organization (IQ(BiO)), might enhance our abilities to generate new desired plant phenotypes...
Integrative analyses of genetic variation in enzyme activities of primary carbohydrate metabolism reveal distinct modes of regulation in Arabidopsis thalianaJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Arboretumlaan, NL 6703 BD Wageningen, The Netherlands
Genome Biol 9:R129. 2008..Quantitative analyses of each trait were performed in the Arabidopsis thaliana Ler x Cvi recombinant inbred line (RIL) population and subjected to correlation and quantitative trait locus (QTL) analysis...
Quantitative genetics in the age of omicsJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, Arboretumlaan 4, NL 6703 BD Wageningen, The Netherlands
Curr Opin Plant Biol 11:123-8. 2008..The progress made in analytical and statistical techniques now allows the construction of regulatory networks that integrate the different levels of the biological information flow from gene-to-function...
Vacuolar invertase regulates elongation of Arabidopsis thaliana roots as revealed by QTL and mutant analysisLidiya I Sergeeva
Laboratory of Plant Physiology, Wageningen University, Arboretumlaan 4, 6703 BD, Wageningen, The Netherlands
Proc Natl Acad Sci U S A 103:2994-9. 2006..Thus, we show the power of QTL analysis, combined for morphological and biochemical traits, followed by fine-mapping and mutant analysis, in unraveling the function of genes and their role in growth and development...
Development of a near-isogenic line population of Arabidopsis thaliana and comparison of mapping power with a recombinant inbred line populationJoost J B Keurentjes
Laboratory of Genetics, Wageningen University, NL 6703 BD, Wageningen, The Netherlands
Genetics 175:891-905. 2007..These analyses are expected to facilitate experimental design for QTL mapping using these two common types of segregating populations...
Histochemical analysis reveals organ-specific quantitative trait loci for enzyme activities in ArabidopsisLidiya I Sergeeva
Laboratory of Plant Physiology, Graduate School Experimental Plant Sciences, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands
Plant Physiol 134:237-45. 2004..Some of this type of loci were also organ specific. It is concluded that QTL analysis based on histochemical data is feasible and may reveal organ-specific loci involved in the regulation of metabolic pathways...
Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometryRic C H De Vos
Plant Research International, Wageningen University and Research Centre Wageningen UR, PO Box 16, 6700 AA Wageningen, The Netherlands
Nat Protoc 2:778-91. 2007..The complete procedure from metabolite extraction to assembly of a data matrix with aligned mass signal intensities takes about 6 days for 50 samples...
Identification of quantitative trait loci controlling symptom development during viral infection in Arabidopsis thalianaOphélie Sicard
UMR Génomique, Diversité et Pouvoir Pathogène, Institut National de la Recherche Agronomique Université Bordeaux 2, IBVM, BP81, 33883 Villenave d Ornon, France
Mol Plant Microbe Interact 21:198-207. 2008..In addition, in the Cvi x Ler RIL population, a digenic recessive determinant controlling PPV infection was identified...
Colonization of the Arabidopsis rhizosphere by fluorescent Pseudomonas spp. activates a root-specific, ethylene-responsive PR-5 gene in the vascular bundleKaren M Leon-Kloosterziel
Faculty of Biology, Graduate School Experimental Plant Sciences, Section Phytopathology, Utrecht University, P O Box 800 84, 3508 TB Utrecht, The Netherlands
Plant Mol Biol 57:731-48. 2005..Together, these results indicate that induction of AtTLP1 is a local response of Arabidopsis roots to colonization by non-pathogenic fluorescent Pseudomonas spp. and is unlikely to play a role in systemic resistance...
MetaNetwork: a computational protocol for the genetic study of metabolic networksJingyuan Fu
Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, NL 9751 NN Haren, The Netherlands
Nat Protoc 2:685-94. 2007..This way MetaNetwork will contribute to a better integration of such data into systems biology...
