J H Veldink

Summary

Affiliation: University Medical Center Utrecht
Country: The Netherlands

Publications

  1. ncbi [Amyotrophic lateral sclerosis]
    J H Veldink
    Afdeling Neurologie van het Universitair Medisch Centrum Utrecht
    Ned Tijdschr Tandheelkd 117:380-2. 2010
  2. ncbi Intake of polyunsaturated fatty acids and vitamin E reduces the risk of developing amyotrophic lateral sclerosis
    J H Veldink
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, G 03 228, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 78:367-71. 2007
  3. ncbi Lack of association between VEGF polymorphisms and ALS in a Dutch population
    P W J van Vught
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Neurology 65:1643-5. 2005
  4. ncbi Physical activity and the association with sporadic ALS
    J H Veldink
    Department of Neurology of the Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Neurology 64:241-5. 2005
  5. ncbi Lifetime occupation, education, smoking, and risk of ALS
    N A Sutedja
    Department of Neurology, G03 228, University Medical Center Utrecht, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Neurology 69:1508-14. 2007
  6. ncbi Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS
    J H Veldink
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    Neurology 56:749-52. 2001
  7. ncbi Inter- and intraindividual variability of riluzole serum concentrations in patients with ALS
    G J Groeneveld
    Neuromuscular Center Utrecht, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neurol Sci 191:121-5. 2001
  8. ncbi Paraplegin mutations in sporadic adult-onset upper motor neuron syndromes
    F Brugman
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurology 71:1500-5. 2008
  9. ncbi Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis
    N A Sutedja
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 82:638-42. 2011
  10. ncbi Riluzole serum concentrations in patients with ALS: associations with side effects and symptoms
    G J Groeneveld
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    Neurology 61:1141-3. 2003

Collaborators

Detail Information

Publications20

  1. ncbi [Amyotrophic lateral sclerosis]
    J H Veldink
    Afdeling Neurologie van het Universitair Medisch Centrum Utrecht
    Ned Tijdschr Tandheelkd 117:380-2. 2010
    ..Only one drug is able to inhibit the progression of the disease to any extent: riluzole. Treatment, therefore, is mainly focused on supportive measures and those which enhance the quality of life optimally...
  2. ncbi Intake of polyunsaturated fatty acids and vitamin E reduces the risk of developing amyotrophic lateral sclerosis
    J H Veldink
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, G 03 228, PO Box 85500, 3508 GA Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 78:367-71. 2007
    ..To assess whether the premorbid dietary intake of fatty acids, cholesterol, glutamate or antioxidants was associated with the risk of developing amyotrophic lateral sclerosis (ALS)...
  3. ncbi Lack of association between VEGF polymorphisms and ALS in a Dutch population
    P W J van Vught
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Neurology 65:1643-5. 2005
    ..No significant association between the previously reported at-risk haplotypes and ALS was found. Pooling our results with the previously studied population still showed a significant association with the AAG haplotype...
  4. ncbi Physical activity and the association with sporadic ALS
    J H Veldink
    Department of Neurology of the Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    Neurology 64:241-5. 2005
    ..001, 7 years earlier), and activity during the last 10 years (p < 0.001, 3 years earlier). CONCLUSIONS: There is no association between physical activity and the risk of developing ALS...
  5. ncbi Lifetime occupation, education, smoking, and risk of ALS
    N A Sutedja
    Department of Neurology, G03 228, University Medical Center Utrecht, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Neurology 69:1508-14. 2007
    ..To investigate the association between cigarette smoking, level of education, occupation, and the occurrence of sporadic amyotrophic lateral sclerosis (ALS)...
  6. ncbi Homozygous deletion of the survival motor neuron 2 gene is a prognostic factor in sporadic ALS
    J H Veldink
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    Neurology 56:749-52. 2001
    ..Increasing the expression of the SMN2 gene may provide a strategy for treatment of motor neuron disease...
  7. ncbi Inter- and intraindividual variability of riluzole serum concentrations in patients with ALS
    G J Groeneveld
    Neuromuscular Center Utrecht, University Medical Center Utrecht, PO Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neurol Sci 191:121-5. 2001
    ..001). Serum levels were not correlated with age or smoking status. The determination of a correlation between riluzole serum concentrations and survival of patients with ALS will be the aim of further studies...
  8. ncbi Paraplegin mutations in sporadic adult-onset upper motor neuron syndromes
    F Brugman
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurology 71:1500-5. 2008
    ..To investigate the frequency of autosomal recessive paraplegin mutations in patients with sporadic adult-onset upper motor neuron (UMN) syndromes...
  9. ncbi Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis
    N A Sutedja
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Neurol Neurosurg Psychiatry 82:638-42. 2011
    ..The authors assessed the association between vascular risk factors and ALS...
  10. ncbi Riluzole serum concentrations in patients with ALS: associations with side effects and symptoms
    G J Groeneveld
    Department of Neurology, University Medical Center Utrecht, The Netherlands
    Neurology 61:1141-3. 2003
    ..It may therefore be advantageous to raise the riluzole dose in patients with low riluzole serum concentrations without the risk of serious side effects...
  11. ncbi Multidisciplinary ALS care improves quality of life in patients with ALS
    J P van den Berg
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
    Neurology 65:1264-7. 2005
    ..To examine the effect of multidisciplinary ALS care on the quality-of-life (QoL) in patients with ALS and their caregivers...
  12. ncbi Family history of neurodegenerative and vascular diseases in ALS: a population-based study
    M H B Huisman
    Department of Neurology, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurology 77:1363-9. 2011
    ....
  13. ncbi Few adverse effects of long-term creatine supplementation in a placebo-controlled trial
    G J Groeneveld
    Department of Neurology, University Medical Centre Utrecht, The Netherlands
    Int J Sports Med 26:307-13. 2005
    ..69 +/- 1.47 before treatment vs. 5.26 +/- 1.44 at the end of treatment) or to a higher prevalence of micro-albuminuria (5.4 % before treatment vs. 1.8 % at the end of treatment)...
  14. ncbi SMN genotypes producing less SMN protein increase susceptibility to and severity of sporadic ALS
    J H Veldink
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center, Utrecht, The Netherlands
    Neurology 65:820-5. 2005
    ....
  15. ncbi Correlates of outcome and response to IVIg in 88 patients with multifocal motor neuropathy
    E A Cats
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht100, 3584 CX Utrecht, The Netherlands
    Neurology 75:818-25. 2010
    ..Identification and examination of all patients with multifocal motor neuropathy (MMN) in the Netherlands to document the clinical spectrum and response to IV immunoglobulin (IVIg) and to determine correlates of outcome...
  16. ncbi Zinc amplifies mSOD1-mediated toxicity in a transgenic mouse model of amyotrophic lateral sclerosis
    G J Groeneveld
    Rudolf Magnus Institute of Neuroscience, Department of Neurology and Neurosurgery, G.03.228, University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands
    Neurosci Lett 352:175-8. 2003
    ..We conclude that zinc sulfate amplifies the mSOD1 transgenic mouse phenotype. This finding may shed more light on the role of zinc in mSOD1-mediated toxicity...
  17. ncbi Increased frequency of HLA-DRB1*15 in patients with multifocal motor neuropathy
    N A Sutedja
    Department of Neurology, G03 228, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Neurology 74:828-32. 2010
    ..We investigated the association of MMN with human leukocyte antigen (HLA) class I and II antigens...
  18. ncbi SMN1 gene duplications are associated with sporadic ALS
    H M Blauw
    Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
    Neurology 78:776-80. 2012
    ..To investigate the role of SMN1 and SMN2 copy number variation and point mutations in amyotrophic lateral sclerosis (ALS) pathogenesis in a large population...
  19. ncbi Sexual differences in onset of disease and response to exercise in a transgenic model of ALS
    J H Veldink
    Department of Neurology, G.03.228 University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, Netherlands
    Neuromuscul Disord 13:737-43. 2003
    ..These results suggest a possible neuroprotective effect of female sex hormones and support the view that ALS patients should not avoid regular exercise...
  20. ncbi [From gene to disease: amyotrophic lateral sclerosis]
    P W J van Vught
    Universitair Medisch Centrum Utrecht, afd. Neurologie, Heidelberglaan 100, 3584 CX Utrecht
    Ned Tijdschr Geneeskd 148:2125-7. 2004
    ..This results in a toxic gain of function. Mutations in the gene coding for alsin, ALS2, have been shown to be responsible for an autosomal recessive form of juvenile ALS...