Research Topics
| I C Van GelderSummaryAffiliation: University Medical Center Groningen Country: The Netherlands Publications
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Detail Information
Publications
Does intensity of rate-control influence outcome in atrial fibrillation? An analysis of pooled data from the RACE and AFFIRM studiesIsabelle C Van Gelder
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
Europace 8:935-42. 2006..The AFFIRM and RACE studies showed that rate control is an acceptable treatment strategy for atrial fibrillation (AF). We examined whether strict rate control offers benefit over more lenient rate control...
Case of the month by the EHRA Education committee: exercise-related arrhythmiasIsabelle C Van Gelder
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
Europace 10:235-7, 256. 2008..This case describes two nephews with exercise-related arrhythmias...
Case of polymorphic ventricular tachycardia after stroke necessitating defibrillationIsabelle C Van Gelder
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
Europace 10:77-8; 124. 2008..This case describes the occurrence of a tachycardia occurring early after a subarachnoid haemorrhage...
[Rhythm control as treatment for patients with medication-resistant atrial fibrillation: maze surgery and percutaneous pulmonary vein isolation by catheter ablation]I C Van Gelder
Universitair Medisch Centrum Groningen, afd Cardiologie, Thoraxcentrum
Ned Tijdschr Geneeskd 150:2294-6. 2006..New techniques have now emerged, including pulmonary vein isolation by means of percutaneous catheter ablation. This is less invasive and therefore nowadays the treatment of first choice if pharmacological rhythm control has failed...
[Non-pharmacological treatment of heart failure: implantable cardioverter defibrillator (ICD) and cardiac resynchronisation therapy]I C Van Gelder
Universitair Medisch Centrum Groningen, Postbus 30 001, 9700, RB Groningen
Ned Tijdschr Geneeskd 150:2238-44. 2006....
The progressive nature of atrial fibrillation: a rationale for early restoration and maintenance of sinus rhythmIsabelle C Van Gelder
Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
Europace 8:943-9. 2006..Although early intervention to limit the progression of this arrhythmia is hindered by the limitations of existing anti-arrhythmic therapies, it is nevertheless a critical goal...
RAte Control Efficacy in permanent atrial fibrillation: a comparison between lenient versus strict rate control in patients with and without heart failure. Background, aims, and design of RACE IIIsabelle C Van Gelder
University Medical Center Groningen, University of Groningen, The Netherlands
Am Heart J 152:420-6. 2006..Recent studies demonstrated that rate control is an acceptable alternative for rhythm control in patients with persistent atrial fibrillation (AF). However, optimal heart rate during AF is still unknown...
Lenient versus strict rate control in patients with atrial fibrillationIsabelle C Van Gelder
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
N Engl J Med 362:1363-73. 2010..We hypothesized that lenient rate control is not inferior to strict rate control for preventing cardiovascular morbidity and mortality in patients with permanent atrial fibrillation...
How to prevent ICD shocks: part ISandra Buck
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands
Europace 10:1110-1. 2008
Rationale and current perspective for early rhythm control therapy in atrial fibrillationIsabelle C Van Gelder
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Europace 13:1517-25. 2011..In the present paper we describe the background of these studies and provide some information on their design...
Prognostic significance of atrial arrhythmias in a primary prevention ICD populationIsabelle C Van Gelder
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Pacing Clin Electrophysiol 34:1070-9. 2011....
Alterations in gene expression of proteins involved in the calcium handling in patients with atrial fibrillationI C Van Gelder
Department of Cardiology, Thoraxcenter, University Hospital Groningen, The Netherlands
J Cardiovasc Electrophysiol 10:552-60. 1999..Abnormalities in the calcium handling in response to tachycardia-induced intracellular calcium overload play a pivotal role in these processes...
Ion channel remodeling is related to intraoperative atrial effective refractory periods in patients with paroxysmal and persistent atrial fibrillationB J Brundel
Department of Cardiology, Thoraxcenter University Hospital Groningen, The Netherlands
Circulation 103:684-90. 2001..We investigated underlying molecular changes by studying the relation between gene expression of the L-type calcium channel and potassium channels and AERP in patients with AF...
Continuous vs episodic prophylactic treatment with amiodarone for the prevention of atrial fibrillation: a randomized trialSheba Ahmed
Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
JAMA 300:1784-92. 2008..Amiodarone effectively suppresses atrial fibrillation but causes many adverse events...
Cardiac gene expression profiling - the quest for an atrium-specific biomarkerA H Maass
Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, 30 001, 9700, RB Groningen, The Netherlands
Neth Heart J 18:610-4. 2010..The identified genes need to be confirmed in human tissue and might ultimately be tested as potential biomarkers for atrial stress. (Neth Heart J 2010;18:610-4.)...
VERDICT: the Verapamil versus Digoxin Cardioversion Trial: A randomized study on the role of calcium lowering for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillationT van Noord
Department of Cardiology, Thoraxcenter, University Hospital Groningen, The Netherlands
J Cardiovasc Electrophysiol 12:766-9. 2001..Median time to recurrence was 5 days (range 0 to 26) versus 8 days (range 2 to 28) (P = NS), respectively. CONCLUSION: Stand-alone intracellular calcium lowering by verapamil around ECV does not enhance cardioversion outcome...
[Life-threatening ventricular tachycardia during flecainide treatment for symptomatic atrial fibrillation in a patient with a structural cardiac disorder]M Rienstra
Universitair Medisch Centrum Groningen, Thoraxcentrum, afd. Cardiologie, RB Groningen
Ned Tijdschr Geneeskd 150:1027-31. 2006..A low-voltage electrocardiogram is suggestive of left ventricular damage. For these patients, electric cardioversion is a better alternative...
[Cardiac rehabilitation in patients with a congenital heart disease, an implantable cardioverter defibrillator or chronic heart failure]J Brügemann
Thoraxcentrum, Academisch Ziekenhuis, Postbus 30 001, 9700 RB Groningen
Ned Tijdschr Geneeskd 148:1809-15. 2004..Patients with stable chronic heart failure should continue their physical training in order to maintain its beneficial physical and psychological effects...
Endothelin system in human persistent and paroxysmal atrial fibrillationB J Brundel
Department of Cardiology, Thoraxcenter University Hospital Groningen, The Netherlands
J Cardiovasc Electrophysiol 12:737-42. 2001..The purpose of this study was to investigate mRNA and protein expression levels of the endothelin system in AF patients with and without concomitant underlying valve disease...
Radiofrequency ablation of atrial fibrillationA C P Wiesfeld
Thoraxcenter, University Hospital Groningen, Department of Cardiology P O Box 30 001, 9700 RB Groningen, The Netherlands
Int J Cardiol 93:231-7. 2004..However, it is only successful in one third of the patients. Further investigations are warranted to identify the ideal patient, as well as to develop better ablation strategies...
Electrical remodeling and atrial dilation during atrial tachycardia are influenced by ventricular rate: role of developing tachycardiomyopathyB A Schoonderwoerd
Department of Cardiology, University Hospital Groningen, The Netherlands
J Cardiovasc Electrophysiol 12:1404-10. 2001..Our aim was to establish the influence of concomitant high ventricular rate and consequent development of CHF on electrical remodeling and dilation during atrial tachycardia...
Pulmonary vein isolation of symptomatic refractory paroxysmal and persistent atrial fibrillation: A single centre and single operator experience in the NetherlandsE S Tan
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Neth Heart J 17:366-72. 2009..Conclusion. Independent determinants of a successful outcome after PVI are paroxysmal AF and a longer left atrial ablation time. (Neth Heart J 2009;17:366-72.)...
[Cardiological (pharmaco)therapy and dental practice]J Brügemann
Cardiologie, Universitair Medisch Centrum Groningen
Ned Tijdschr Tandheelkd 113:75-81. 2006..In case of urgent and/or extended dental procedures, admittence to a hospital must be considered to secure optimal therapy...
Cardiac gene expression profiling - the quest for an atrium-specific biomarkerA H Maass
Departments of Cardiology and Experimental Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Neth Heart J 18:610-4. 2010..The identified genes need to be confirmed in human tissue and might ultimately be tested as potential biomarkers for atrial stress. (Neth Heart J 2010;18:610-4.)...
Current treatment recommendations in antiarrhythmic therapyI C Van Gelder
Department of Cardiology, Thoraxcenter, University Hospital Groningen, The Netherlands
Drugs 55:331-46. 1998..This may imply that an increasing number of patients will be candidates for such a device. However, it will be necessary to await publication of data involving these devices from current ongoing studies...
Paroxysmal atrial fibrillation, quality of life and neuroticismM P van den Berg
Department of Cardiology, Thorax Centre, Groningen University Medical Centre, Groningen, The Netherlands
Neth J Med 63:170-4. 2005..We sought to investigate the potential role of neuroticism in the impairment of QoL in patients with paroxysmal AF...
Planning and monitoring of patients for electrical cardioversion for atrial fibrillationJ H H Deuling
Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
Neth Heart J 20:148-54. 2012....
Phlebotomies as a treatment of serious heart failure due to haemochromatosis: a case reportR V H P Huijskes
Department of Cardiology, Medical Center Leeuwarden, The Netherlands
Neth Heart J 17:438-41. 2009..Neth Heart J 2009;17:438-41.)...
Evaluation of global left ventricular function assessment of non-fluorescent electromechanical endocardial mapping compared with biplane left ventricular contrast angiographyE S Tan
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Neth Heart J 18:72-7. 2010..Neth Heart J 2010;18:72-77.)...
Cardiac resynchronisation therapy and the role of optimal device utilisationS Buck
Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Neth Heart J 17:354-7. 2009..By optimising programming of the device response to cardiac resynchronisation, therapy can be improved. (Neth Heart J 2009;17:354-7.)...
Predictors of ventricular tachyarrhythmia in high-risk myocardial infarction patients treated with primary coronary interventionJ R Timmer
Department of Cardiology, Thorax Center, University Medical Center Groningen, Groningen currently Department of Cardiology, Isala Klinieken, Zwolle, The Netherlands
Neth Heart J 18:122-8. 2010..Independent predictors of VT are younger age, TIMI 0-1 flow prior to PCI and larger infarct size. The presence of early VT was not significantly associated with one-year mortality. (Neth Heart J 2010;18:122-8.)...
Alterations in potassium channel gene expression in atria of patients with persistent and paroxysmal atrial fibrillation: differential regulation of protein and mRNA levels for K+ channelsB J Brundel
Department of Cardiology, Thoraxcenter University Hospital Groningen, The Netherlands
J Am Coll Cardiol 37:926-32. 2001..Our purpose was to determine whether patients with persistent atrial fibrillation (AF) and patients with paroxysmal AF show alterations in potassium channel expression...
Broad complex tachycardia during treatment of atrial fibrillation with a 1c antiarrhythmic drug: ventricular or supraventricular proarrhythmia?A C P Wiesfeld
Int J Cardiol 107:140-1. 2006
Treatment of atrial fibrillationY Blaauw
Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands
Heart 88:432-7. 2002
Dronedarone for the control of ventricular rate in permanent atrial fibrillation: the Efficacy and safety of dRonedArone for the cOntrol of ventricular rate during atrial fibrillation (ERATO) studyJean Marc Davy
Cardiology Department, University Hospital, CHU Montpellier, Montpellier, France
Am Heart J 156:527.e1-9. 2008....
Human SCN5A gene mutations alter cardiac sodium channel kinetics and are associated with the Brugada syndromeM B Rook
Department of Medical Physiology, Utrecht University, The Netherlands
Cardiovasc Res 44:507-17. 1999..This syndrome is associated with a high mortality rate and has been shown to display familial occurrence...
[Arrhythmogenic right-ventricular cardiomyopathy: different manifestations as precursors of sudden death which might be prevented]P van der Harst
Academisch Ziekenhuis, Postbus 30.001, 9700 RB, Groningen
Ned Tijdschr Geneeskd 148:2396-402. 2004..Furthermore, since genetics play an important role and ARVC can be asymptomatic, evaluation of close relatives for preclinical symptoms is important...
