Research Topics
Species | Iris E SommerSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
Healthy individuals with auditory verbal hallucinations; who are they? Psychiatric assessments of a selected sample of 103 subjectsIris E C Sommer
Neuroscience Division University Medical Center Utrecht, B01 206, Rudolf Magnus School for Neuroscience, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Schizophr Bull 36:633-41. 2010..Our data suggest that AVH in otherwise healthy individuals are not an isolated phenomenon but part of a general vulnerability for schizophrenia...
Effects of cross-sex hormones on cerebral activation during language and mental rotation: An fMRI study in transsexualsI E C Sommer
Rudolf Magnus Institute of Neuroscience, Brain Division, University Medical Center Utrecht, The Netherlands
Eur Neuropsychopharmacol 18:215-21. 2008..54, p=0.34), but post-treatment testosterone levels correlated to total activation during mental rotation (rho=0.64, p=0.01). Findings suggest that sex steroids may influence cerebral activation, but lateralization remains stable...
Nonsteroidal anti-inflammatory drugs in schizophrenia: ready for practice or a good start? a meta-analysisIris E Sommer
B01 206 Neuroscience Department, University Medical Center Utrecht, Heidelberglaan 100 3584CX Utrecht, The Netherlands
J Clin Psychiatry 73:414-9. 2012..This article quantitatively summarizes the efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) to augment antipsychotic treatment to reduce schizophrenia symptom severity...
Formal thought disorder in non-clinical individuals with auditory verbal hallucinationsIris E Sommer
The Neuroscience Division University Medical Center Utrecht, Rudolf Magnus School for Neuroscience, Netherlands
Schizophr Res 118:140-5. 2010..The hypothesis of a shared neurobiological basis would be strengthened by the presence of FTD in individuals who frequently experience AVH, but do not meet DSM-IV criteria for a psychotic disorder...
Auditory verbal hallucinations predominantly activate the right inferior frontal areaIris E C Sommer
Neuroscience Division, University Medical Center Utrecht and Rudolf Magnus Institute for Neuroscience, Heidelberglaan, Netherlands
Brain 131:3169-77. 2008..The predominant engagement of the right inferior frontal area during AVH may be related to the typical low semantic complexity and negative emotional content...
Sex differences in handedness, asymmetry of the planum temporale and functional language lateralizationIris E Sommer
Neuroscience Division of the University Medical Center Utrecht, The Netherlands
Brain Res 1206:76-88. 2008..In conclusion, males are more frequently non-right handed than females, but there is no sex difference in asymmetries of the Planum Temporale, dichotic listening or functional imaging findings during language tasks...
Psychiatric morbidity and X-chromosomal origin in a Klinefelter sampleMarco P M Boks
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, Utrecht, The Netherlands
Schizophr Res 93:399-402. 2007..Nevertheless, these findings provide further support for the role of the X-chromosome in the susceptibility to psychiatric disorders in general and psychotic disorders in particular...
Do mood symptoms subdivide the schizophrenia phenotype? Association of the GMP6A gene with a depression subgroupMarco P M Boks
Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
Am J Med Genet B Neuropsychiatr Genet 147:707-11. 2008..Overall, these finding suggests that investigating subgroups of schizophrenia based symptoms profile and particularly mood symptoms can facilitate genetic studies of schizophrenia...
The relationship of DNA methylation with age, gender and genotype in twins and healthy controlsMarco P Boks
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands
PLoS ONE 4:e6767. 2009..The identification of CpG loci of which DNA methylation levels are under genetic control or are related to age or gender will facilitate further studies into the role of DNA methylation and disease...
The Measurement of Language Lateralization with Functional Transcranial Doppler and Functional MRI: A Critical EvaluationMetten Somers
Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht Utrecht, Netherlands
Front Hum Neurosci 5:31. 2011..Our results suggest that fTCD can be a valid alternative for fMRI to measure lateralization, particularly when costs or mobility are important factors in the study design...
Language lateralization in female patients with schizophrenia: an fMRI studyI E C Sommer
Department of Neuroscience, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
Schizophr Res 60:183-90. 2003..These findings indicate that lower language lateralization in women is not likely to underlie gender differences in schizophrenia...
Language lateralization in monozygotic twin pairs concordant and discordant for handednessI E C Sommer
Rudolf Magnus Institute of Neuroscience, Department of Psychiatry, Neuroscience Division, University Medical Centre Utrecht, The Netherlands
Brain 125:2710-8. 2002..Discordant language dominance may be caused by a relatively late time of splitting of the original embryo, which disrupts the normal development of left-right asymmetry...
Efficacy of slow repetitive transcranial magnetic stimulation in the treatment of resistant auditory hallucinations in schizophrenia: a meta-analysisAndre Aleman
BCN Neuroimaging Center, University Medical Center Groningen, University of Groningen, The Netherlands
J Clin Psychiatry 68:416-21. 2007..Several studies have now been reported regarding the efficacy of TMS treatment, but results were inconsistent. Therefore, meta-analytic integration of the published trials is needed to evaluate the prospects of this new treatment...
