Research Topics
Species | M M RoversSummaryAffiliation: University Medical Center Utrecht Country: The Netherlands Publications
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Detail Information
Publications
Bayes' theorem: a negative example of a RCT on grommets in children with glue earMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre, Utrecht, The Netherlands
Eur J Epidemiol 20:23-8. 2005..The results showed that our trial had little or no impact on the beliefs of the ENT-surgeons, i.e. they did not adjust their belief to the extent that was expected according to Bayes' theorem...- Grommets in otitis media with effusion: an individual patient data meta-analysisM M Rovers
Julius Center for Health Sciences and Primary Care and Department of Pediatrics, University Medical Center Utrecht, Netherlands
Arch Dis Child 90:480-5. 2005..To identify subgroups of children with otitis media with effusion (OME) that might benefit more than others from treatment with ventilation tubes... - Otitis mediaMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre, PO Box 85060, 3508 AB, Utrecht, Netherlands
Lancet 363:465-73. 2004..The ideal intervention for OM, however, does not yet exist, and an urgent need remains to explore new and creative options based on modern insights into the pathophysiology of OM... - Is asthma in 2-12 year-old children associated with physician-attended recurrent upper respiratory tract infections?Eelko Hak
Julius Center for Health Science and Primary Care, University Medical Center, Utrecht, The Netherlands
Eur J Epidemiol 18:899-902. 2003..5, 95% confidence interval: 1.1-6.1). As a consequence, antibiotic prescriptions and referrals to hospitals occurred more frequently among asthmatics than controls... - Seasonal variation in the prevalence of persistent otitis media with effusion in one-year-old infantsM M Rovers
Department of Otorhinolaryngology, University Medical Centre, St Radboud, Nijmegen, The Netherlands
Paediatr Perinat Epidemiol 14:268-74. 2000..8% [95% CI 4.3, 5.2]. The highest prevalence (8.0%) was found in April, and the lowest (1.5%) in October. Rates of bilateral OME during the late winter months were twice as high as those during the late summer... - Long-term prognosis of acute otitis media in infancy: determinants of recurrent acute otitis media and persistent middle ear effusionRoger A M J Damoiseaux
Julius Center of Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Fam Pract 23:40-5. 2006..No sufficiently discriminatory prognostic model could be constructed for either outcome measure. CONCLUSION: Prediction of recurrent acute otitis media or persistent middle ear effusion in individual young children remains poor... - Current indications for adenoidectomy in a sample of children in the NetherlandsM T A van den Aardweg
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, Utrecht, The Netherlands
B-ENT 6:15-8. 2010..To study current indications for adenoidectomy in Dutch children... - Recurrent childhood upper respiratory tract infections do not reduce the risk of adult atopic diseaseW A F Balemans
Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
Clin Exp Allergy 36:198-203. 2006..Longitudinal studies investigating these associations beyond childhood are, however, scarce... - Mannose-binding lectin and upper respiratory tract infections in children and adolescents: a reviewJopje M Ruskamp
Department of Pediatric Immunology, Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:482-6. 2006..Large prospective cohort studies with regular documentation of URI and possible confounders such as atopy and environmental factors are required to establish the role of MBL polymorphisms in susceptibility for URI... - International perspectives on management of acute otitis media: a qualitative reviewAnne G M Schilder
Department of Otorhinolaryngology KE 04 140 5, Wilhelmina Children s Hospital, University Medical Center Utrecht, P O Box 85090, 3508 AB, Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 68:29-36. 2004..With antibiotic resistance rising and more evidence regarding the limited clinical efficacy of antibiotics becoming available, interest in managing AOM other than with antibiotics is renewed... - Effect of adenotonsillectomy on middle ear status in childrenKarin P Q Oomen
Department of Otorhinolaryngology, Wilhelmina Children's Hospital, University Medical Center Utrecht, The Netherlands
Laryngoscope 115:731-4. 2005.... - Incidence of GP-diagnosed respiratory tract infections according to age, gender and high-risk co-morbidity: the Second Dutch National Survey of General PracticeE Hak
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Fam Pract 23:291-4. 2006..Figures on GP-diagnosed respiratory tract infections (RTI) are outdated because of demographic changes and increase in co-morbid conditions, respiratory vaccination programmes and change in illness behaviour... - The effect of short-term ventilation tubes versus watchful waiting on hearing in young children with persistent otitis media with effusion: a randomized trialM M Rovers
Department of Otorhinolaryngology, University Medical Centre, Nijmegen, The Netherlands
Ear Hear 22:191-9. 2001..This is probably due to partial recurrent OME in the VT group and to partial spontaneous recovery in the WW group... - Polymorphisms in the mannan-binding lectin gene are not associated with questionnaire-reported respiratory tract infections in childrenJopje M Ruskamp
Department of Pediatrics, Wilhelmina Children s Hospital, University Medical Center Utrecht, University of Utrecht, Lundlaan 6, Utrecht, The Netherlands
J Infect Dis 198:1707-13. 2008..Large-scale replication of previous associations is needed, however. We investigated the association between MBL2 polymorphisms and the frequency of RTI in a large population-based birth cohort of white children... - The burden of otitis mediaMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Vaccine 26:G2-4. 2008..Conclusive evidence is, however, lacking. More insight into the individual risk factors is required in order to answer the question of why some children recover from OM spontaneously while others need specific intervention... - Predictors of chronic suppurative otitis media in childrenErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:1115-8. 2006..To determine which factors predict development of chronic suppurative otitis media (CSOM) in children... - Antibiotics for acute otitis media: a meta-analysis with individual patient dataMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
Lancet 368:1429-35. 2006..We aimed to identify subgroups of children who would and would not benefit more than others from treatment with antibiotics... - Prediction of asthma in young adults using childhood characteristics: Development of a prediction ruleWalter A F Balemans
Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre Utrecht, KH 01 419 0, PO Box 85090, Lundlaan 6, 3508 AB Utrecht, The Netherlands
J Clin Epidemiol 59:1207-12. 2006..To develop an easily applicable prediction rule for asthma in young adulthood using childhood characteristics... - Trimethoprim-sulfamethoxazole in children with chronic otitis media: a randomized comparison of costs and effectsChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
Otol Neurotol 29:961-4. 2008..To study the cost-effectiveness of a 6- to 12-week course of high-dose oral trimethoprim-sulfamethoxazole in children with chronic active otitis media (COM)... - Antibiotic therapy to prevent the development of asymptomatic middle ear effusion in children with acute otitis media: a meta-analysis of individual patient dataLaura Koopman
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 134:128-32. 2008..To determine predictors of the development of asymptomatic middle ear effusion (MEE) in children with acute otitis media (AOM) and to assess the effect of antibiotic therapy in preventing the development of MEE in these children... - A systematic review of analytical methods used to study subgroups in (individual patient data) meta-analysesLaura Koopman
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, Stratenum 6 131, PO Box 85500, 3508 GA Utrecht, The Netherlands
J Clin Epidemiol 60:1002-9. 2007..To determine whether individual patient data meta-analyses (IPDMA) are used to perform subgroup analyses and to study whether the analytical methods regarding subgroup analyses differ between IPDMA and conventional meta-analyses (CMA)... - Empirical comparison of subgroup effects in conventional and individual patient data meta-analysesLaura Koopman
University Medical Center Utrecht, Utrecht, The Netherlands
Int J Technol Assess Health Care 24:358-61. 2008..Our objective is to compare such subgroup effects using the data of six trials (n = 1,643) on the effectiveness of antibiotics in children with acute otitis media (AOM)... - Is pacifier use a risk factor for acute otitis media? A dynamic cohort studyMaroeska M Rovers
Julius Center for Health Science and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
Fam Pract 25:233-6. 2008..Recently, the use of a pacifier has been identified as a risk factor for acute otitis media (AOM). The studies performed so far, however, suffer from methodological limitations... - Predictors of pain and/or fever at 3 to 7 days for children with acute otitis media not treated initially with antibiotics: a meta-analysis of individual patient dataMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
Pediatrics 119:579-85. 2007..The goal was to determine the predictors of a prolonged course for children with acute otitis media... - Effectiveness of trimethoprim/sulfamethoxazole for children with chronic active otitis media: a randomized, placebo-controlled trialErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, Netherlands
Pediatrics 119:897-904. 2007..The goal was to determine the clinical effectiveness of prolonged outpatient treatment with trimethoprim/sulfamethoxazole for children with chronic active otitis media... - Comparison of methods of handling missing data in individual patient data meta-analyses: an empirical example on antibiotics in children with acute otitis mediaLaura Koopman
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Am J Epidemiol 167:540-5. 2008..In the authors' empirical example, imputation within trials appears to be the most appropriate approach of handling missing data in individual patient data meta-analyses... - Effect of long-term trimethoprim/sulfamethoxazole treatment on resistance and integron prevalence in the intestinal flora: a randomized, double-blind, placebo-controlled trial in childrenErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, The Netherlands
J Antimicrob Chemother 63:1011-6. 2009..The aim of this study was to test the hypothesis that trimethoprim/sulfamethoxazole selects for integron-positive and multidrug-resistant Enterobacteriaceae in the intestinal flora... - Influence of sampling technique on detection of potential pathogens in the nasopharynxErwin L van der Veen
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 132:752-5. 2006..To determine the optimal approach for nasopharyngeal culture and to establish which approach children tolerate best... - Open and closed endotracheal suction systems in mechanically ventilated intensive care patients: a meta-analysisIrene P Jongerden
Department of Medicine, Division of Internal Medicine and Infectious Diseases, Eijkman Winkler Centre for Medical Microbiology, University Medical Center Utrecht, 3508 GA Utrecht, The Netherlands
Crit Care Med 35:260-70. 2007..Yet effectiveness regarding patient safety and costs of these systems has not been carefully analyzed... - Intranasal corticosteroid monotherapy in acute rhinosinusitis: an evidence-based case reportRoderick P Venekamp
Julius Center for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:783-8. 2010.... - Interventions in health care professionals to improve treatment in children with upper respiratory tract infectionsChantal W B Boonacker
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 74:1113-21. 2010..To assess the effectiveness of these interventions, and when more are effective--which works best. And to analyse the costs associated with these interventions... - Effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy: open, randomised controlled trialBirgit K van Staaij
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, 3508 AB Utrecht, Netherlands
BMJ 329:651. 2004..12 children had complications related to surgery. CONCLUSION: Adenotonsillectomy has no major clinical benefits over watchful waiting in children with mild symptoms of throat infections or adenotonsillar hypertrophy... - Subgroup effects despite homogeneous heterogeneity test resultsRolf H H Groenwold
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
BMC Med Res Methodol 10:43. 2010..Lack of demonstrable statistical heterogeneity, however, might obscure clinical heterogeneity, meaning clinically relevant subgroup effects... - Measuring disease-specific health-related quality of life to evaluate treatment outcomes in tinnitus patients: a systematic reviewDigna M Kamalski
Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 143:181-5. 2010..To identify all disease-specific health-related quality-of-life (HR-QoL) instruments used to assess tinnitus in clinical trials and detail their psychometric properties... - Ventilator-associated pneumonia and mortality: a systematic review of observational studiesWilhelmina G Melsen
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Crit Care Med 37:2709-18. 2009..Ventilator-associated pneumonia is generally believed to increase the mortality of patients. This notion is predominantly based on the results of observational studies... - Influence of single-trial results on clinical practice: example of adenotonsillectomy in childrenMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, 3508 AB Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 135:970-5. 2009.... - Recurrence up to 3.5 years after antibiotic treatment of acute otitis media in very young Dutch children: survey of trial participantsNatália Bezáková
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO Box 85060, 3508 AB Utrecht, Netherlands
BMJ 338:b2525. 2009..To determine the long term effects of antibiotic treatment for acute otitis media in young children... - Translating research evidence into action in daily practiceMaroeska M Rovers
Julius Centrum for Health Sciences and Primary Care, Department of Otolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:29-30. 2010..These efforts may also prove to be very helpful to identify evidence gaps and provide recommendations for research priorities in otolaryngology... - Risk factors for otitis media: an international perspectiveMaroeska M Rovers
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 139, P O Box 85060, 3508 AB Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 70:1251-6. 2006..It is not known how this is to be explained, whether by cultural differences or by other factors, such as variation in environmental risk factors for OM... - Persistence of upper respiratory tract infections in a cohort followed from childhood to adulthoodMaroeska M Rovers
Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, The Netherlands
Fam Pract 23:286-90. 2006.... - The diagnostic value of diffusion-weighted magnetic resonance imaging in detecting a residual cholesteatomaMark C J Aarts
Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 143:12-6. 2010.... - Is a positive family history predictive for recurrent acute otitis media in children? An evidence-based case reportMonique Albersen
Julius Centre for Health Sciences and Primary Care, Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:31-5. 2010..Family history increases the absolute risk, but not in a way that it will help to predict rAOM accurately... - Alterations of the oropharyngeal microbial flora after adenotonsillectomy in children: a randomized controlled trialThuy My Le
Julius Center for Health Sciences and Primary Care, Department of Otorhinolaryngology, E 04 140 5, Wilhelmina Children s Hospital, University Medical Center Utrecht, PO Box 85090, 3590 AB Utrecht, The Netherlands
Arch Otolaryngol Head Neck Surg 133:969-72. 2007.... - Differences in mortality on the basis of complete blood count in an unselected population at the emergency departmentKaren Vroonhof
Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
Lab Hematol 12:134-8. 2006..7 g/dL, p < .01), for men no difference was observed.In conclusion, our study shows clinically relevant differences in mortality in hematological parameters in an unselected population at the ED, irrespective of underlying pathology... - Trends in doctor consultations, antibiotic prescription, and specialist referrals for otitis media in children: 1995-2003Astrid I O Plasschaert
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Pediatrics 117:1879-86. 2006..The rising antibiotic prescription rate for otitis media causes concern, because this may induce increasing medical costs and antibiotic resistance... - Exploring the role of polymorphisms in ficolin genes in respiratory tract infections in childrenJ M Ruskamp
Department of Paediatrics, Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
Clin Exp Immunol 155:433-40. 2009..In conclusion, at a population level, genetic variation in ficolin genes FCN2 and FCN3 do not seem to contribute to the risk of RTI in Caucasian children... - Accuracy and feasibility of daily infrared tympanic membrane temperature measurements in the identification of fever in childrenBirgit K van Staaij
Julius Center for Health Sciences and Primary Care, University Medical Center stratenum 6 131, PO Box 85060, 3508 AB Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 67:1091-7. 2003..The infrared tympanic membrane thermometer (ITT) seems ideal for measuring central body temperature. Its accuracy, however, is still debated, and the feasibility of daily temperature measurements with an ITT has not been described... - Atopic disease and exhaled nitric oxide in an unselected population of young adultsCharlotte J J van Asch
Department of Paediatric Respiratory Medicine, Wilhelmina Children s Hospital, University Medical Centre, Utrecht, The Netherlands
Ann Allergy Asthma Immunol 100:59-65. 2008..However, the independent influence of different atopic entities (eczema, allergic rhinitis, and asthma) on FeNO has never been studied in the general population... - Differences in mortality on the basis of laboratory parameters in an unselected population at the Emergency DepartmentKaren Vroonhof
Department of Clinical Chemistry and Laboratory Medicine, University Medical Center Utrecht, The Netherlands
Clin Chem Lab Med 43:536-41. 2005..Therefore, glucose and lactate should be routinely added to a blood gas request. Our study shows differences in mortality for laboratory parameters in patients visiting the emergency department, irrespective of the underlying pathology... - Effect of pneumococcal vaccination on otitis media with effusion in children older than 1 yearThuy My Le
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands
Eur J Pediatr 166:1049-52. 2007..Therefore, these vaccinations are not indicated in the prevention of OME in these children... - Adenoidectomy and/or tonsillectomy in childhood is not associated with atopic disease later in lifeE S van Hattum
Department of Pediatric Respiratory Medicine, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
Clin Exp Allergy 36:40-3. 2006..52-1.64), RR 0.94 (CL 0.68-1.30), and RR 1.00 (CL 0.59-1.68), respectively. CONCLUSIONS: Our data show no association between adenoidectomy and/or tonsillectomy in childhood and the incidence of atopic disease in young adults... - Loss of antibodies and response to (re-)vaccination in children after treatment for acute lymphocytic leukemia: a systematic reviewC M van Tilburg
Wilhelmina Children s Hospital, University Medical Centre Utrecht, Utrecht, The Netherlands
Leukemia 20:1717-22. 2006..Memory is preserved but revaccination may be warranted. This is the first systematic review and the best possible current approximation of chemotherapy-induced immune damage in children after ALL treatment... - Alterations in the nasopharyngeal bacterial flora after adenoidectomy in children: a systematic reviewJohanna W M Aarts
Department of Otorhinolaryngology, Wilhelmina Children s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands
Otolaryngol Head Neck Surg 142:15-20.e1. 2010..To review the current literature on alterations in the nasopharyngeal bacterial flora in relation to adenoidectomy in children with recurrent upper respiratory tract infections (rURTIs)... - Penicillin for acute sore throat in children: randomised, double blind trialSjoerd Zwart
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Stratenum 6 131, PO Box 85060, 3508 AB Utrecht, Netherlands
BMJ 327:1324. 2003..To assess the effectiveness of penicillin for three days and treatment for seven days compared with placebo in resolving symptoms in children with sore throat... - The association between intrauterine inflammation and spontaneous vaginal delivery at term: a cross-sectional studyMichiel L Houben
Department of Pediatrics, Wilhelmina Children s Hospital, Utrecht University Medical Center, Utrecht, The Netherlands
PLoS ONE 4:e6572. 2009..The role of intrauterine inflammation, although implicated in preterm birth, is not yet established in human term labor. We hypothesized that intrauterine inflammation at term is associated with spontaneous onset of labor... - A systematic review of diagnostic criteria for acute mastoiditis in childrenMaaike T A van den Aardweg
Department of Otorhinolaryngology, University Medical Centre Utrecht, Utrecht, The Netherlands
Otol Neurotol 29:751-7. 2008..To review systematically the literature for the current criteria and strategies used to diagnose acute mastoiditis in children... - Effectiveness of adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy: open, randomised controlled trialBirgit K van Staaji
Clin Otolaryngol 30:60-3. 2005..12 children had surgery related complications. CONCLUSION: Adenotonsillectomy in children with mild symptoms of throat infections or adenotonsillar hypertrophy has no major clinical benefits over watchful waiting... - Chronic suppurative otitis media: a reviewMonique Verhoeff
Department of Otorhinolaryngology (KE04.140.5, Wilhelmina Children's Hospital, University Medical Centre Utrecht, P.O. Box 85090, 3508 AB Utrecht, The Netherlands
Int J Pediatr Otorhinolaryngol 70:1-12. 2006..There is also a need for further well-designed studies on the effectiveness of various management strategies for CSOM... - Representativeness of trial populations: an example from a trial of adenotonsillectomy in childrenEmma H van den Akker
Department of Otorhinolaryngology, Wilhelmina Children's Hospital Utrecht, The Netherlands
Acta Otolaryngol 123:297-301. 2003..The trial population appears to be representative of the relevant patient domain, i.e. children currently undergoing adenotonsillectomy in The Netherlands... - Reliability and validity of functional health status and health-related quality of life questionnaires in children with recurrent acute otitis mediaCarole N M Brouwer
Department of Paediatrics, Spaarne Hospital, Postbus 770, 2130 AT Hoofddorp, The Netherlands
Qual Life Res 16:1357-73. 2007..Apart from the generic TAIQOL subscales, both generic and disease-specific questionnaires used in this study showed good psychometric qualities and responsiveness for use in clinical studies on children with rAOM... - Quality of life in children with undiagnosed and diagnosed asthmaRene van Gent
Department of Pediatrics, Maxima Medical Centre, P O Box 7777, 5500 MB Veldhoven, The Netherlands
Eur J Pediatr 166:843-8. 2007..05), with highest absence rate in those with diagnosed asthma. In conclusion, both undiagnosed and diagnosed asthma have a significant impact on the quality of life of both children and their caregivers... - Effect of pneumococcal vaccination on quality of life in children with recurrent acute otitis media: a randomized, controlled trialCarole N M Brouwer
Department of Pediatrics, Spaarne Hospital Haarlem, Haarlem, Netherlands
Pediatrics 115:273-9. 2005..CONCLUSION: Pneumococcal vaccination has no beneficial effect compared with control vaccination on either HRQoL or FHS in children 1 to 7 years old with RAOM... - Recent advances in otitis media. 1. Epidemiology, natural history, and risk factorsKathleen A Daly
Department of Otolaryngology, University of Minnesota, Minneapolis, USA
Ann Otol Rhinol Laryngol Suppl 194:8-15. 2005 - Long-term effects of pediatric adenotonsillectomy on serum immunoglobulin levels: results of a randomized controlled trialEmma H van den Akker
Department of Otorhinolaryngology, Wilhelmina Children's Hospital/University Medical Center Utrecht, The Netherlands
Ann Allergy Asthma Immunol 97:251-6. 2006..This finding indicates that the remaining mucosa-associated lymphoid tissue can compensate for the loss of tonsil and adenoid tissue... - Otitis media meta-analysisMaroeska M Rovers
Pediatrics 114:508-9; author reply 508-9. 2004 - Excessive body weight is associated with additional loss of quality of life in children with asthmaRene van Gent
Maxima Medical Center, Department of Pediatrics, Veldhoven, The Netherlands
J Allergy Clin Immunol 119:591-6. 2007..Asthma and excessive body weight frequently coexist, whereas the exact relationship between the 2 diseases is unknown... - Health-related quality of life in children with otitis mediaCarole N M Brouwer
Department of Paediatrics, Spaarne Hospital Hoofddorp, Postbus 770, 2130 AT Hoofddorp, The Netherlands
Int J Pediatr Otorhinolaryngol 69:1031-41. 2005.... - No differences in physical activity in (un)diagnosed asthma and healthy controlsRene van Gent
Maxima Medical Center, Department of Pediatrics, Veldhoven, The Netherlands
Pediatr Pulmonol 42:1018-23. 2007..Childhood asthma does not appear to be associated with a decreased level of daily physical activity in our study population...