Detail Information
Publications
Ventilator-induced endothelial activation and inflammation in the lung and distal organsMaria A Hegeman
Laboratory of Psychoneuroimmunology, University Medical Center Utrecht, Utrecht, 3584 EA, The Netherlands
Crit Care 13:R182. 2009..The present study was designed to investigate whether alveolar stretch due to mechanical ventilation (MV) may evoke endothelial activation and inflammation in healthy mice, not only in the lung but also in organs distal to the lung...
Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injuryMaria A Hegeman
Laboratory of Neuroimmunology and Developmental Origins of Disease, Department of Pediatric Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands
PLoS ONE 5:e15653. 2010..Moreover, we evaluated whether treatment with Ang-1, a Tie2 receptor agonist, protects against inflammation, vascular leakage and impaired gas exchange induced by mechanical ventilation...
