Research Topics
| C A BoucherSummaryAffiliation: University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assayC A Boucher
Department of Virology, Eijkman Winkler Institute, University Hospital Utrecht, The Netherlands
Antimicrob Agents Chemother 40:2404-9. 1996....
Replication of a pre-existing resistant HIV-1 subpopulation in vivo after introduction of a strong selective drug pressureM D de Jong
Department of Virology, Academic Medical Centre, University of Amsterdam, The Netherlands
Antivir Ther 1:33-41. 1996..The extensive repercussions for subsequent treatment of even a minor subpopulation of naturally occurring drug-resistant variants observed in this study must be considered in future therapeutic strategies...
Multicenter comparison of three commercial methods for quantification of human immunodeficiency virus type 1 RNA in plasmaR Schuurman
Eijkman Winkler Institute for Medical Microbiology, Department of Virology, Utrecht University, The Netherlands
J Clin Microbiol 34:3016-22. 1996..In all assays, similar changes in plasma HIV-1 RNA concentrations were determined for longitudinally collected clinical samples...
The dominant source of CD4+ and CD8+ T-cell activation in HIV infection is antigenic stimulationJ W Cohen Stuart
Department of Virology, Eijkman Winkler Institute, University Medical Center, Utrecht, The Netherlands
J Acquir Immune Defic Syndr 25:203-11. 2000..Persistence of HIV antigens may explain why T-cell activation fails to revert to levels found in healthy individuals after 48 weeks of therapy...
Clinical diagnosis of influenza virus infection: evaluation of diagnostic tools in general practiceL J van Elden
Department of Virology, Eijkman Winkler Institute for Microbiology, Infectious Diseases and Inflammation, The Netherlands
Br J Gen Pract 51:630-4. 2001..Respiratory virus infections are difficult to distinguish on clinical grounds. General practitioners (GPs) however, still depend on their clinical judgement...
Transient relapses ("blips") of plasma HIV RNA levels during HAART are associated with drug resistanceJ W Cohen Stuart
Department of Virology, Eijkman-Winkler Institute, University Medical Center, Utrecht, The Netherlands
J Acquir Immune Defic Syndr 28:105-13. 2001..Independent of the mechanism, blips did not preclude successful inhibition of viral replication during 2-year follow-up in the majority of these cases...
