Research Topics
| E J T RutgersSummaryAffiliation: The Netherlands Cancer Institute Country: The Netherlands Publications
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Detail Information
Publications
Sentinel node biopsy: interpretation and management of patients with immunohistochemistry-positive sentinel nodes and those with micrometastasesEmiel J T Rutgers
Department of Surgery, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
J Clin Oncol 26:698-702. 2008..Protocols that identify lymph node metastasis, from which the clinical relevance is known, are warranted. Unnecessary lymph node dissections should be avoided...
Behavioral and psychosocial effects of rapid genetic counseling and testing in newly diagnosed breast cancer patients: design of a multicenter randomized clinical trialMarijke R Wevers
Division of Psychosocial Research and Epidemiology, The Netherlands Cancer Institute, PO Box 90203, 1006 BE Amsterdam, The Netherlands
BMC Cancer 11:6. 2011..The aim of this study is to determine the effect of RGCT on treatment decisions and on psychosocial health...
Sentinel node identification rate and nodal involvement in the EORTC 10981-22023 AMAROS trialMarieke E Straver
Department of Surgical Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Ann Surg Oncol 17:1854-61. 2010..The aim of the current substudy was to evaluate the identification rate and the nodal involvement...
Sentinel node micrometastasis in breast cancerE J T Rutgers
Department of Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Br J Surg 91:1241-2. 2004
Ductal carcinoma in situ of the breast; diagnostic assessment and treatmentE J Th Rutgers
Department of Surgery, Pathology, and Radiation Oncology, Netherlands Cancer Institute, Amsterdam
Scand J Surg 91:268-72. 2002
Guidelines to assure quality in breast cancer surgeryE J Th Rutgers
Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Eur J Surg Oncol 31:568-76. 2005..The outcome of the different procedures can be measured according to simple criteria and prospective registration. All possible surgical procedures, the indication-objectives, the training-objectives and outcome measures are described...
Sentinel node procedure in breast carcinoma: a valid tool to omit unnecessary axillary treatment or even more?E J T Rutgers
Department of Surgery, The Netherlands Cancer Institute/Antoni van Leeuwenhoek ziekenhuis, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Eur J Cancer 40:182-6. 2004
Follow-up care in breast cancerEmiel J Rutgers
Department of Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Expert Rev Anticancer Ther 4:212-8. 2004..For more complex issues, such as debilitating functional treatment regimens, estrogen deprivation symptoms, pregnancy after breast cancer or symptoms suspicious for a relapse, an experienced oncologist should be at hand...
Clinical trials update of the European Organization for Research and Treatment of Cancer Breast Cancer GroupEmiel J T Rutgers
Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Breast Cancer Res 6:165-9. 2004....
The EORTC 10041/BIG 03-04 MINDACT trial is feasible: Results of the pilot phaseEmiel Rutgers
The Netherlands Cancer Institute, Department of Surgery, Amsterdam, The Netherlands
Eur J Cancer 47:2742-9. 2011..We present the results of the pilot phase consisting of first 800 patients included...
Excision biopsy of breast lesions changes the pattern of lymphatic drainageS H Estourgie
Department of Surgery, Academic Medical Centre, Meibergdreef 9, Amsterdam, The Netherlands
Br J Surg 94:1088-91. 2007..The aim was to validate the sentinel node biopsy procedure in women who had previous breast excision biopsy by means of determining the reproducibility of lymphoscintigraphy after surgery...
Risk of invasion and axillary lymph node metastasis in ductal carcinoma in situ diagnosed by core-needle biopsyP Meijnen
Department of Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Br J Surg 94:952-6. 2007..The data were used to select criteria for patients in whom sentinel node (SN) biopsy might be indicated...
Marking the axilla with radioactive iodine seeds (MARI procedure) may reduce the need for axillary dissection after neoadjuvant chemotherapy for breast cancerM E Straver
Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Br J Surg 97:1226-31. 2010..The aim was to assess a new surgical method for evaluating the axillary response to chemotherapy...
The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of ageS Mook
Department of Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, The Netherlands
Ann Oncol 21:717-22. 2010..The aim of this study was to evaluate the prognostic value of the 70-gene prognosis signature for early events in postmenopausal patients...
Validation of 70-gene prognosis signature in node-negative breast cancerJ M Bueno-de-Mesquita
Department of Pathology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands
Breast Cancer Res Treat 117:483-95. 2009....
Randomized trial of high-dose chemotherapy and hematopoietic progenitor-cell support in operable breast cancer with extensive lymph node involvement: final analysis with 7 years of follow-upJ G Schrama
Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam
Ann Oncol 13:689-98. 2002....
Stage of breast cancers found during the surveillance of women with a familial or hereditary riskR Kaas
Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands
Eur J Surg Oncol 34:501-7. 2008..To compare the breast cancer stages found during MG alone surveillance in women at increased risk with those detected in a program where MRI was added...
Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signatureM Knauer
Division of Diagnostic Oncology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, Amsterdam NL 1066CX, The Netherlands
Br J Cancer 103:1788-93. 2010..However, the majority of patients does not recur and might thus be overtreated with adjuvant systemic therapy. We investigated whether the 70-gene MammaPrint signature identifies HER-2-positive patients with favourable outcome...
The hidden sentinel node in breast cancerP J Tanis
Department of Surgery, The Netherlands Cancer Institute, Amsterdam
Eur J Nucl Med Mol Imaging 29:305-11. 2002..Delayed imaging and re-injection of the radioactive tracer increase the visualisation rate. The non-visualised sentinel node can be identified intraoperatively in more than half of the patients...
Effects of patient selection on the applicability of results from a randomised clinical trial (EORTC 10853) investigating breast-conserving therapy for DCISN Bijker
Department of Radiation Oncology, The Netherlands Cancer Institute Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Br J Cancer 87:615-20. 2002..Selection of patients may explain the differences in outcome of the randomised patients, and those not-entered. Thus, the results of this trial may not be applicable to all patients with ductal carcinoma in situ...
The influence of tamoxifen treatment on the oestrogen receptor in metachronous contralateral breast cancerR Kaas
Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Ziekenhuis Plesmanlaan, Amsterdam, The Netherlands
Br J Cancer 88:707-10. 2003..045). In conclusion, metachronous CBCs developing after 1-3 years of tamoxifen treatment are more often ER-negative breast cancers. So far this does not seem to have a major impact on survival...
Adjuvant therapy for breast cancerS Rodenhuis
Departments of Medical Oncology and Surgical Oncology, The Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Br J Surg 93:1443-5. 2006
Axillary and extra-axillary lymph node recurrences after a tumor-negative sentinel node biopsy for breast cancer using intralesional tracer administrationIris M C van der Ploeg
Department of Surgery, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066, CX, Amsterdam, The Netherlands
Ann Surg Oncol 15:1025-31. 2008..The objective of the present study of sentinel node-negative breast cancer patients was to determine the lymph node recurrence rates in the axilla and elsewhere, the false-negative rates, and the survival...
Ultrasonography and fine-needle aspiration cytology can spare breast cancer patients unnecessary sentinel lymph node biopsyMaartje C van Rijk
Department of Surgery, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, CX, 1066, The Netherlands
Ann Surg Oncol 13:31-5. 2006..The aims of this study were to evaluate the sensitivity of preoperative ultrasonography and fine-needle aspiration cytology for detecting axillary metastases and to assess how often sentinel node biopsy could be avoided...
Sentinel node biopsy before neoadjuvant chemotherapy spares breast cancer patients axillary lymph node dissectionMaartje C van Rijk
Department of Surgery, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, CX, 1066, The Netherlands
Ann Surg Oncol 13:475-9. 2006..In our institute, sentinel lymph node biopsy is performed before neoadjuvant chemotherapy. The aim of this study was to evaluate our experience with this approach...
Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER)Jolien M Bueno de Mesquita
Department of Pathology, Division of Diagnostic Oncology, Netherlands Cancer Institute, Amsterdam, Netherlands
Lancet Oncol 8:1079-87. 2007....
Effects of lycopene on the insulin-like growth factor (IGF) system in premenopausal breast cancer survivors and women at high familial breast cancer riskDorien W Voskuil
Division of Experimental Therapy and the Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
Nutr Cancer 60:342-53. 2008..However, lycopene effects were discordant between the 2 study populations showing beneficial effects in high-risk healthy women but not in breast cancer survivors...
Differences between first and subsequent rounds of the MRISC breast cancer screening program for women with a familial or genetic predispositionMieke Kriege
The Rotterdam Family Cancer Clinic, Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Rotterdam, Netherlands
Cancer 106:2318-26. 2006..As results of these subsequent screening rounds were most predictive for long-term effects, the authors expect that this screening program will contribute to a decrease of breast cancer mortality in these high-risk women...
Prognostic factors and evaluation of surgical management of hepatic metastases from colorectal origin: a 10-year single-institute experienceEduard L A R Mutsaerts
Department of Surgery, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, 1066 CX Amsterdam, The Netherlands
J Gastrointest Surg 9:178-86. 2005..Our data suggest there is no strong predictor of survival. Survival seems to decrease with increasing number of metastases found on computed tomography...
Efficacy of MRI and mammography for breast-cancer screening in women with a familial or genetic predispositionMieke Kriege
Rotterdam Family Cancer Clinic, Department of Medical Oncology, Erasmus Medical Center-Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
N Engl J Med 351:427-37. 2004..4 percent (P<0.001) and 56.4 percent (P=0.001) in the two control groups. CONCLUSIONS: MRI appears to be more sensitive than mammography in detecting tumors in women with an inherited susceptibility to breast cancer...
Individualization of therapy using Mammaprint: from development to the MINDACT TrialStella Mook
Netherlands Cancer Institute, Amsterdam, The Netherlands
Cancer Genomics Proteomics 4:147-55. 2007....
Factors affecting sensitivity and specificity of screening mammography and MRI in women with an inherited risk for breast cancerMieke Kriege
Family Cancer Clinic, Department of Medical Oncology, Erasmus MC-Daniel den Hoed Cancer Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands
Breast Cancer Res Treat 100:109-19. 2006..227) and for women with a low breast density (0.237). CONCLUSIONS: This report supports the earlier recommendation that MRI should be a standard screening method for breast cancer in BRCA1/2 mutation carriers...
Are short-term or long-term recurrence rates more important in breast cancer screening?Emiel J T Rutgers
Ann Intern Med 149:357; author reply 357-8. 2008
