Research Topics
| H van GoorSummaryAffiliation: Radboud University Nijmegen Medical Centre Country: The Netherlands Publications
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Detail Information
Publications
Complicated Intra-Abdominal Infections Observational European study (CIAO Study)Massimo Sartelli
Department of Surgery, Macerata Hospital, Italy
World J Emerg Surg 6:40. 2011..The CIAO study is a multicenter, observational study and will be carried out in various surgical departments throughout Europe. The study will include patients undergoing surgery or interventional drainage for complicated IAI...- Bologna Guidelines for Diagnosis and Management of Adhesive Small Bowel Obstruction (ASBO): 2010 Evidence-Based Guidelines of the World Society of Emergency SurgeryFausto Catena
Emergency Surgery Unit, Department of General and Multivisceral Transplant Surgery, S, Orsola Malpighi University Hospital, Bologna, Italy
World J Emerg Surg 6:5. 2011..abstract:.. - WSES consensus conference: Guidelines for first-line management of intra-abdominal infectionsMassimo Sartelli
Department of Surgery, Macerata Hospital, Italy
World J Emerg Surg 6:2. 2011..This document represents the executive summary of the final guidelines approved by the consensus conference... - Pancreatitis, very early compared with normal start of enteral feeding (PYTHON trial): design and rationale of a randomised controlled multicenter trialOlaf J Bakker
Dept, of OR Evidence Based Surgery, Radboud University Nijmegen Medical Centre, PO 9101, 6500 HB Nijmegen The Netherlands
Trials 12:73. 2011..A start of enteral nutrition (EN) within 24 hours of onset may reduce the number of infections as compared to the current practice of starting an oral diet and EN if necessary at 3-4 days after admission... - Electrocautery causes more ischemic peritoneal tissue damage than ultrasonic dissectionRichard P G Ten Broek
Department of Surgery, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
Surg Endosc 25:1827-34. 2011..Ultrasonic dissection seems to reduce tissue damage. This study aimed to compare electrocautery and ultrasonic dissection in terms of peritoneal tissue ischemia measured by microdialysis... - Minimally invasive 'step-up approach' versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a randomised controlled multicenter trial [ISRCTN13975868]Marc G H Besselink
Department of Surgery, University Medical Center Utrecht, The Netherlands
BMC Surg 6:6. 2006..So far, these strategies have never been compared in a randomised controlled trial. The PANTER study (PAncreatitis, Necrosectomy versus sTEp up appRoach) was conceived to yield the evidence needed for a considered policy decision... - Oxidised- and total non-protein bound glutathione and related thiols in gallbladder bile of patients with various gastrointestinal disordersWilbert H M Peters
Department of Gastroenterolgy, Radboud University Medical Center, Nijmegen, The Netherlands
BMC Gastroenterol 7:7. 2007..In this study we report on the levels of non-protein bound thiols in gallbladder bile of patients with various gastrointestinal disorders... - Laparoscopic reintervention in colorectal surgeryR P G Ten Broek
Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Minerva Chir 63:161-8. 2008..Improved diagnostic tools for mapping adhesions will also facilitate patient selection for laparoscopic treatment of SBO... - Consequences and complications of peritoneal adhesionsH van Goor
Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Colorectal Dis 9:25-34. 2007.... - Selective cyclo-oxygenase 2 inhibition affects ileal but not colonic anastomotic healing in the early postoperative periodI H J T de Hingh
Department of Surgery, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Br J Surg 93:489-97. 2006..The latter was confirmed in rats with colonic anastomoses only. CONCLUSION: In this model, administration of the COX-2 inhibitor celecoxib affected ileal but not colonic anastomotic healing in the early postoperative period... - No detrimental effects of repeated laparotomies on early healing of experimental intestinal anastomosesI H J T de Hingh
Department of Surgery, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
Int J Colorectal Dis 20:534-41. 2005..CONCLUSIONS: In this experimental setting, early anastomotic healing is not adversely affected by repeated laparotomies... - Early anastomotic repair in the rat intestine is affected by transient preoperative mesenteric ischemiaL A E Posma
Department of Surgery, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands
J Gastrointest Surg 13:1099-106. 2009..Recent preclinical studies reveal that the strength of intestinal anastomoses can be compromised after reperfusion. So far, this phenomenon has not been investigated in the very first days of healing when wound strength is lowest... - Repair of giant midline abdominal wall hernias: "components separation technique" versus prosthetic repair : interim analysis of a randomized controlled trialT S de Vries Reilingh
Department of Surgery, Radboud University Nijmegen Medical Center, PO Box 9101, 6500 HB Nijmegen, The Netherlands
World J Surg 31:756-63. 2007..It was the aim of this study to compare the "components separation technique" (CST) versus prosthetic repair with e-PTFE patch (PR)... - Timing and impact of infections in acute pancreatitisM G Besselink
Department of Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands
Br J Surg 96:267-73. 2009..Although infected necrosis is an established cause of death in acute pancreatitis, the impact of bacteraemia and pneumonia is less certain... - Plasminogen activator, but not systemic antibiotic therapy, prevents abscess formation in an experimental model of secondary peritonitisO R Buyne
Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Br J Surg 95:1287-93. 2008..They are an important target for prevention and treatment during or after surgical treatment of peritonitis. Experimental data suggest that fibrinolytic therapy may be effective when antibiotics are not... - The omentum-polypropylene sandwich technique: an attractive method to repair large abdominal-wall defects in the presence of contamination or infectionR P Bleichrodt
Department of Surgery, Radboud University Nijmegen Medical Center, Huispost 690, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Hernia 11:71-4. 2007..The present report describes an alternative technique for repair of heavily contaminated abdominal-wall defects... - Timing of cholecystectomy after mild biliary pancreatitisO J Bakker
Department of Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands
Br J Surg 98:1446-54. 2011..The aim of the study was to evaluate recurrent biliary events as a consequence of delay in cholecystectomy following mild biliary pancreatitis... - Polyanionic polysaccharides reduce intra-abdominal adhesion and abscess formation in a rat peritonitis modelM M Reijnen
Department of Surgery, University Medical Center Nijmegen, Nijmegen, The Netherlands
J Surg Res 101:248-53. 2001..We have assessed the adhesion- and abscess-reducing capacity of various solution volumes and concentrations of two polyanionic polysaccharides, hyaluronan (HA) and carboxymethylcellulose (CMC), in a rat peritonitis model... - Both tissue-type plasminogen activator and urokinase prevent intraabdominal abscess formation after surgical treatment of peritonitis in the ratO R Buyne
Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Surgery 144:66-73. 2008..Fibrinolytic therapy may be effective in this respect. The efficacy of recombinant tissue plasminogen activator (rtPA) and urokinase is compared in a preclinical model for surgical treatment of peritonitis... - Autologous tissue repair of large abdominal wall defectsT S de Vries Reilingh
Department of Surgery, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Br J Surg 94:791-803. 2007..Pedicled or free vascularized flaps are reserved for complex situations... - Hyaluronan-based antiadhesive membrane has no major effect on intraperitoneal growth of colonic tumour cellsC J J M Sikkink
Department of Surgery, University Medical Centre St Radboud, Nijmegen, The Netherlands
Eur Surg Res 36:123-8. 2004..CONCLUSION: HA-carboxymethylcellulose bioresorbable membrane has no major effect on intraperitoneal tumour implantation and growth in an experimental model... - Adhesion formation and reherniation differ between meshes used for abdominal wall reconstructionC J J M Sikkink
Department of Surgery, Radboud University Nijmegen Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands
Hernia 10:218-22. 2006..Rats in the PPM/HA/CMC had the highest tensile strength. PPM/HA/CMC approaches the demands of the ideal mesh best, having superior antiadhesive properties, no reherniation and no infection in this rat model of incisional hernia... - Sodium hyaluronate increases the fibrinolytic response of human peritoneal mesothelial cells exposed to tumor necrosis factor alphaM M Reijnen
Department of Surgery, University Hospital Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Arch Surg 136:291-6. 2001..Sodium hyaluronate interferes with the fibrin degrading capacity of human peritoneal mesothelial cells exposed to tumor necrosis factor (TNF) alpha... - Pathophysiology of intra-abdominal adhesion and abscess formation, and the effect of hyaluronanM M P J Reijnen
Department of Surgery, University Medical Centre St Radboud, Nijmegen, The Netherlands
Br J Surg 90:533-41. 2003..The aim of this review was to investigate the pathophysiology of intra-abdominal adhesions and abscesses, and to explore the possible sites of action of hyaluronan... - Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitisI H J T de Hingh
Department of Surgery, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Br J Surg 90:981-8. 2003..This experimental finding lends support to recent clinical studies that have demonstrated the feasibility of constructing a primary anastomosis under these conditions... - Increased sympathetic activity in chronic pancreatitis patients is associated with hyperalgesiaH C J L Buscher
Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
J Pain Palliat Care Pharmacother 24:362-6. 2010..042). In severe chronic pancreatitis patients, increased sympathetic activity and hyperalgesia appear associated, suggesting that sympathetic activity may also play a role in these patients' pain... - Enhanced recovery after surgery (ERAS) versus conventional postoperative care in colorectal surgeryPascal H E Teeuwen
Department of Surgery, Division of Gastro intestinal Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
J Gastrointest Surg 14:88-95. 2010..In a cohort study, mortality, morbidity, and length of stay were compared between ERAS patients and carefully matched historical controls... - Repair of large midline incisional hernias with polypropylene mesh: comparison of three operative techniquesT S de Vries Reilingh
Department of Surgery, University Medical Center Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands
Hernia 8:56-9. 2004..22). Repair of large midline incisional hernias with the use of a polypropylene mesh carries a high risk of complications and has a high reherniation rate. The underlay technique seems to be the better technique... - Effect of thoracoscopic splanchnic denervation on pain processing in chronic pancreatitis patientsH C J L Buscher
Department of General Surgery, Radboud University Nijmegen Medical Centre, P O B 9101, Internal 520, 6500 HB Nijmegen, The Netherlands
Eur J Pain 11:437-43. 2007..Using quantitative sensory testing (QST), this first study investigates whether thoracoscopic splanchnic denervation (TSD), performed to reduce nociceptive visceral input, affects central sensitisation in chronic pancreatitis patients... - Time course of peritoneal tissue plasminogen activator after experimental colonic surgery: effect of hyaluronan-based antiadhesive agents and bacterial peritonitisM M P J Reijnen
Department of Surgery, University Medical Centre Nijmegen, Nijmegen, The Netherlands
Br J Surg 89:103-9. 2002..This study assessed the peritoneal fibrinolytic response during the first week after colonic surgery in rats with and without bacterial peritonitis, and possible modulation of the response by two hyaluronan-based antiadhesive agents... - Feasibility of minimally invasive approaches in patients with infected necrotizing pancreatitisM G Besselink
Department of Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands
Br J Surg 94:604-8. 2007..Minimally invasive procedures to treat infected necrotizing pancreatitis (INP) are gaining popularity. The proportion of patients suitable for this approach remains unknown... - Interventional management of abdominal sepsis: when and howH van Goor
Department of Surgery, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Langenbecks Arch Surg 387:191-200. 2002..relaparotomy "on demand," intra-abdominal hypertension, and primary and delayed abdominal wall closure techniques after operation for severe intra-abdominal infection... - Pancreas-preserving total duodenectomy versus standard pancreatoduodenectomy for patients with familial adenomatous polyposis and polyps in the duodenumS M M de Castro
Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands
Br J Surg 95:1380-6. 2008..This study analysed the results of PPTD in the Netherlands and reviewed the relevant literature... - Decreased levels of mucosal detoxification enzymes in the pouch of patients with familial adenomatous polyposisP Friederich
Department of Gastroenterology, Radboud University Medical Centre, Nijmegen, The Netherlands
Br J Surg 93:1108-14. 2006..CONCLUSION: After IPAA, GST detoxification activity in the pouch is significantly lower than that in the afferent ileal loop, which may promote tumorigenesis... - Invited commentary on "Fast track open aortic surgery: reduced postoperative stay with a goal directed pathway". towards aneurysm repair in day-care?J Adam van der Vliet
Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
Eur J Vasc Endovasc Surg 34:279-80. 2007 - Diagnosis and treatment of acute appendicitis in children: a survey among Dutch surgeons and comparison with evidence-based practiceE C T H Tan
Department of General Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, P O Box 9101, 690, 6500, 6500 HB, The Netherlands
World J Surg 30:512-8; discussion 519. 2006..A national survey provides insight into daily surgical practice and enables comparison of practice with the available evidence... - Long-term results of bilateral thoracoscopic splanchnicectomy in patients with chronic pancreatitisH C J L Buscher
Department of Surgery, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Br J Surg 89:158-62. 2002..CONCLUSION: Bilateral thoracoscopic splanchnicectomy alleviated pain in patients with chronic pancreatitis. It was associated with a low morbidity rate and no deaths. Pain eventually recurred in approximately 50 per cent... - Guideline proposal to reconstructive surgery for complex perineal sinus or rectal fistulaJ W P M Oomen
Department of Gastrointestinal Surgery, Radboud University Medical Centre Nijmegen, Nijmegen, The Netherlands
Int J Colorectal Dis 22:225-30. 2007..To evaluate a guideline approach of reconstructive surgery for complex perineal sinus or rectal fistula... - [The treatment of gallstone disease in the elderly]S van Assen
afd. Algemene Interne Geneeskunde, Universitair Medisch Centrum St Radboud, Postbus 9101, 6500 HB Nijmegen
Ned Tijdschr Geneeskd 147:146-50. 2003..After removal of common bile duct stones (whether or not accompanied by cholangitis or pancreatitis) a laparoscopic cholecystectomy should be performed, unless contraindications are present... - Pharmacological management of pain in chronic pancreatitisA A J van Esch
Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Center, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands
Dig Liver Dis 38:518-26. 2006..The treatment of chronic pancreatic pain requires a multidisciplinary approach that tailors the various therapeutic options to meet the need of the individual patient... - Adhesions and colorectal surgery - call for actionM C Parker
Darent Valley Hospital, Dartford, Kent, UK
Colorectal Dis 9:66-72. 2007..The paper acts as a 'call for action' to colorectal surgeons to make prevention of adhesions more of a priority and importantly to inform patients of the risks associated with adhesion-related complications during the consent process... - Granulocyte-colony stimulating factor in the prevention of postoperative infectious complications and sub-optimal recovery from operation in patients with colorectal cancer and increased preoperative risk (ASA 3 and 4). Protocol of a controlled clinical tB Stinner
Department of General Surgery, Philipps-University Marburg, Germany
Inflamm Res 50:233-48. 2001..This new type of a single-centre trial aims to reduce the gap between animal experiments and clinical trials or--if it fails--at least demonstrates new ways for explaining the failures...