Research Topics
| D G SnijdelaarSummaryAffiliation: Radboud University Nijmegen Medical Centre Country: The Netherlands Publications
| Collaborators |
Detail Information
Publications
Methadone for phantom limb painLonneke Bergmans
Pain Center, Department of Anesthesiology, University Medical Center, Nijmegen, The Netherlands
Clin J Pain 18:203-5. 2002..RESULTS AND CONCLUSIONS: Administration of oral methadone may be of value in the treatment of phantom limb pain; controlled clinical trials would be appropriate to verify this observation...
Effects of perioperative oral amantadine on postoperative pain and morphine consumption in patients after radical prostatectomy: results of a preliminary studyDirk G Snijdelaar
Acute Pain Research Unit, Department of Anesthesia and Pain Management, Toronto General Hospital, Ontario, Canada
Anesthesiology 100:134-41. 2004..The aim of this pilot study was to evaluate the effects of perioperative oral amantadine on postoperative pain and analgesic consumption...
A randomised, controlled study of peri-operative low dose s(+)-ketamine in combination with postoperative patient-controlled s(+)-ketamine and morphine after radical prostatectomyD G Snijdelaar
Department of Anesthesiology Pain Centre, University Medical Centre Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Anaesthesia 59:222-8. 2004..049). Pain scores at rest were significantly lower in the ketamine/morphine group across the 48-h study period (p = 0.01). No significant differences were found in pressure algometry measurements or the occurrence of adverse effects...
Effects of pre-treatment with amantadine on morphine induced antinociception during second phase formalin responses in ratsDirk G Snijdelaar
Department of Anesthesiology Pain Centre, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Pain 119:159-67. 2005....
Isoflurane attenuates pulmonary interleukin-1beta and systemic tumor necrosis factor-alpha following mechanical ventilation in healthy miceM Vaneker
Departments of Anesthesiology and Intensive Care, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Acta Anaesthesiol Scand 53:742-8. 2009..Isoflurane is known to have protective immunological effects on different organ systems. We tested the hypothesis that the MV-induced inflammatory response in healthy lungs is reduced by isoflurane...
Pre-emptive analgesia using intravenous fentanyl plus low-dose ketamine for radical prostatectomy under general anesthesia does not produce short-term or long-term reductions in pain or analgesic useJoel Katz
Department of Psychology and School of Kinesiology and Health Science, York University, Toronto, Ont, Canada
Pain 110:707-18. 2004..Pre-operative, low-dose administration of i.v. ketamine did not result in a clinically meaningful reduction in pain or morphine consumption when compared with post-incisional administration of ketamine or a saline control condition...
Mechanical ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settingsMichiel Vaneker
Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Anesthesiology 107:419-26. 2007..To study mechanotransduction in vivo, the authors used an animal MV model with clinically relevant ventilator settings, avoiding alveolar damage...
Hypercapnic acidosis attenuates the pulmonary innate immune response in ventilated healthy miceFeico J J Halbertsma
Maxima Medical Centre, Veldhoven, The Netherlands
Crit Care Med 36:2403-6. 2008....
Low-tidal-volume mechanical ventilation induces a toll-like receptor 4-dependent inflammatory response in healthy miceMichiel Vaneker
Department of Anesthesiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Anesthesiology 109:465-72. 2008..A role for proinflammatory pathways has been proposed. The current studies analyzed the roles of Toll-like receptor (TLR) 4 and TLR2 involvement in the inflammatory response after MV in the healthy lung...
