J H M Berden

Summary

Affiliation: Radboud University Nijmegen Medical Centre
Country: The Netherlands

Publications

  1. ncbi Lupus nephritis: a nucleosome waste disposal defect?
    Jo H M Berden
    Nephrology Research Laboratory, Nijmegen Center for Molecular Life Sciences Division of Nephrology, University Medical Center, Nijmegen, The Netherlands
    J Nephrol 15:S1-10. 2002
  2. ncbi Discontinuation of immunosuppression in proliferative lupus nephritis: is it possible?
    Cecile Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Centre, 464, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Nephrol Dial Transplant 21:1465-9. 2006
  3. ncbi The role of dendritic cells in the pathogenesis of systemic lupus erythematosus
    Justin H Fransen
    Nephrology Research Laboratory, Nijmegen Centre for Molecular Life Sciences, Department of Nephrology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Arthritis Res Ther 12:207. 2010
  4. ncbi Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study
    Jessica J Manson
    Centre for Rheumatology Research, University College London, Windeyer Institute, 46 Cleveland Street, London W1T 4JF, UK
    Arthritis Res Ther 11:R154. 2009
  5. ncbi Segmental and Global Subclasses of Class IV Lupus Nephritis Have Similar Renal Outcomes
    Catharina M Haring
    Department of Nephrology 464, Radboud University, Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Am Soc Nephrol 23:149-54. 2012
  6. ncbi Lupus nephritis: consequence of disturbed removal of apoptotic cells?
    J H M Berden
    Nephrology Research Laboratory, Nijmegen Centre for Molecular Life Sciences and Division of Nephrology 545, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Neth J Med 61:233-8. 2003
  7. ncbi Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist
    C Grootscholten
    Division of Nephrology, University Medical Center, Nijmegen, The Netherlands
    Qual Life Res 12:635-44. 2003
  8. ncbi Glomerular hyperfiltration in type 1 diabetes mellitus results from primary changes in proximal tubular sodium handling without changes in volume expansion
    G Vervoort
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Clin Invest 35:330-6. 2005
  9. ncbi Decreased phagocytosis of apoptotic cells in diseased SLE mice
    R Licht
    Division of Nephrology 545, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    J Autoimmun 22:139-45. 2004
  10. ncbi Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial
    C Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Kidney Int 70:732-42. 2006

Collaborators

  • P Smits
  • J F M Wetzels
  • G Vervoort
  • R H W M Derksen
  • R Licht
  • Cecile Grootscholten
  • F H J van den Hoogen
  • F J Snoek
  • Marc Bijl
  • Henry Dijkman
  • Dirk J Lefeber
  • A Roos
  • Vicki Levidiotis
  • Johan van der Vlag
  • Tessa J M Wijnhoven
  • Catharina M Haring
  • Justin H Fransen
  • Jessica J Manson
  • T J M Wijnhoven
  • Toin H van Kuppevelt
  • Joost F M Lensen
  • Angelique L W M M Rops
  • Lambert P W J van den Heuvel
  • Godfried W van der Heijden
  • J van der Vlag
  • J W C Dieker
  • Anke Rietveld
  • Jan A J G van den Brand
  • Gosse J Adema
  • Jurjen Ruben
  • Luuk B Hilbrands
  • Lesley J Mason
  • David A Isenberg
  • Anisur Rahman
  • David P D'Cruz
  • Alexander Ma
  • Pauline Rogers
  • M J W van den Hoven
  • T H van Kuppevelt
  • H Ding
  • X Xu
  • M Schwartz
  • R A Prinz
  • E J Lewis
  • Ronnie G P Wismans
  • Mabel J W van den Hoven
  • Hans-Jacob Bangstad
  • Hans Jacob Bangstad
  • Svein O Kolset
  • Per Pfeffer
  • Sylviane Muller
  • Peter de Boer
  • Jürgen W Dieker
  • Didi D M Braat
  • Alwin A H A Derijck

Detail Information

Publications24

  1. ncbi Lupus nephritis: a nucleosome waste disposal defect?
    Jo H M Berden
    Nephrology Research Laboratory, Nijmegen Center for Molecular Life Sciences Division of Nephrology, University Medical Center, Nijmegen, The Netherlands
    J Nephrol 15:S1-10. 2002
    ..Via their cationic histone part nucleosomes can bind to heparan sulfate, a strong anionic constituent of the glomerular basement membrane...
  2. ncbi Discontinuation of immunosuppression in proliferative lupus nephritis: is it possible?
    Cecile Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Centre, 464, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Nephrol Dial Transplant 21:1465-9. 2006
  3. ncbi The role of dendritic cells in the pathogenesis of systemic lupus erythematosus
    Justin H Fransen
    Nephrology Research Laboratory, Nijmegen Centre for Molecular Life Sciences, Department of Nephrology, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands
    Arthritis Res Ther 12:207. 2010
    ....
  4. ncbi Relationship between anti-dsDNA, anti-nucleosome and anti-alpha-actinin antibodies and markers of renal disease in patients with lupus nephritis: a prospective longitudinal study
    Jessica J Manson
    Centre for Rheumatology Research, University College London, Windeyer Institute, 46 Cleveland Street, London W1T 4JF, UK
    Arthritis Res Ther 11:R154. 2009
    ..We assessed how well anti-alpha-actinin, anti-nucleosome and anti-double-stranded DNA (anti-dsDNA) antibodies reflected renal outcome measures in patients with new-onset LN followed for up to 2 years...
  5. ncbi Segmental and Global Subclasses of Class IV Lupus Nephritis Have Similar Renal Outcomes
    Catharina M Haring
    Department of Nephrology 464, Radboud University, Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Am Soc Nephrol 23:149-54. 2012
    ..In conclusion, the rate of doubling of serum creatinine concentration or of ESRD did not differ between patients with class IV-S and those with IV-G lupus nephritis...
  6. ncbi Lupus nephritis: consequence of disturbed removal of apoptotic cells?
    J H M Berden
    Nephrology Research Laboratory, Nijmegen Centre for Molecular Life Sciences and Division of Nephrology 545, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Neth J Med 61:233-8. 2003
    ..This nephritogenic potential is due to the binding of the positively charged histone components of the nucleosome to the negatively charged heparan sulphate (HS) within the GBM. This incites glomerular inflammation...
  7. ncbi Health-related quality of life in patients with systemic lupus erythematosus: development and validation of a lupus specific symptom checklist
    C Grootscholten
    Division of Nephrology, University Medical Center, Nijmegen, The Netherlands
    Qual Life Res 12:635-44. 2003
    ..A significant change in number of symptoms and total distress level was found. It is concluded that the SSC has satisfactory psychometric properties and appears suitable for both clinical and research purposes...
  8. ncbi Glomerular hyperfiltration in type 1 diabetes mellitus results from primary changes in proximal tubular sodium handling without changes in volume expansion
    G Vervoort
    Department of General Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Eur J Clin Invest 35:330-6. 2005
    ..Recently it was hypothesized that an increase in sodium reabsorption may lead to glomerular hyperfiltration through the tubulo-glomerular feedback mechanism (tubular-hypothesis) without volume expansion...
  9. ncbi Decreased phagocytosis of apoptotic cells in diseased SLE mice
    R Licht
    Division of Nephrology 545, University Medical Center Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    J Autoimmun 22:139-45. 2004
    ..In conclusion, during disease progression in murine SLE, apoptotic cell clearance becomes impaired, which might amplify further disease progression...
  10. ncbi Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial
    C Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Kidney Int 70:732-42. 2006
    ..At last follow-up, there were no differences in serum creatinine or proteinuria between the two groups. However, since our study lacked sufficient power, longer follow-up is needed to reveal putative differences...
  11. ncbi Sodium-lithium countertransport is increased in normoalbuminuric type 1 diabetes but is not related to other risk factors for microangiopathy
    G Vervoort
    University Medical Center Nijmegen, Nijmegen, The Netherlands
    Eur J Clin Invest 32:93-9. 2002
    ..We studied kinetic parameters of Na/Li CT activity together with other putative risk factors for microangiopathy in normoalbuminuric type 1 diabetic patients and matched control subjects...
  12. ncbi Triggers for anti-chromatin autoantibody production in SLE
    J W C Dieker
    Nephrology Research Laboratory, Nijmegen Center for Molecular Life Sciences, and Division of Nephrology University Medical Center, Nijmegen, The Netherlands
    Lupus 11:856-64. 2002
    ..This deposition incites glomerulonephritis, the most serious manifestation of SLE...
  13. ncbi Heparanase induces a differential loss of heparan sulphate domains in overt diabetic nephropathy
    T J M Wijnhoven
    Department of Matrix Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Diabetologia 51:372-82. 2008
    ..Our present study addresses whether heparan sulphate with different modifications is differentially reduced in the GBM and whether heparanase selectively cleaves heparan sulphate with different domain specificities...
  14. ncbi Deposition of nucleosomal antigens (histones and DNA) in the epidermal basement membrane in human lupus nephritis
    Cecile Grootscholten
    University Medical Center, Nijmegen, The Netherlands
    Arthritis Rheum 48:1355-62. 2003
    ..Nucleosomes and histones have been identified in glomerular deposits in human lupus nephritis. We investigated whether nucleosomes are present in the basement membrane of nonlesional skin of lupus patients...
  15. ncbi Health-related quality of life and treatment burden in patients with proliferative lupus nephritis treated with cyclophosphamide or azathioprine/ methylprednisolone in a randomized controlled trial
    Cecile Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    J Rheumatol 34:1699-707. 2007
    ..We expected better HRQOL during AZA treatment...
  16. ncbi Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis
    Cecile Grootscholten
    Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Arthritis Rheum 56:924-37. 2007
    ....
  17. ncbi A prospective study of anti-chromatin and anti-C1q autoantibodies in patients with proliferative lupus nephritis treated with cyclophosphamide pulses or azathioprine/methylprednisolone
    Cecile Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Ann Rheum Dis 66:693-6. 2007
    ....
  18. ncbi Aberrant heparan sulfate profile in the human diabetic kidney offers new clues for therapeutic glycomimetics
    Tessa J M Wijnhoven
    Department of Matrix Biochemistry and Nephrology Research Laboratory, Nijmegen Centre for Molecular Life Sciences, The Netherlands
    Am J Kidney Dis 48:250-61. 2006
    ..The aim of this study is to immuno(histo)chemically profile HSs from microalbuminuric kidneys from patients with type 1 diabetes and identify specific structural HS alterations associated with early diabetic nephropathy...
  19. ncbi Interobserver agreement of scoring of histopathological characteristics and classification of lupus nephritis
    Cecile Grootscholten
    Division of Nephrology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Nephrol Dial Transplant 23:223-30. 2008
    ..Assessing renal biopsies from patients with lupus nephritis (LN) is a difficult task and it is subject to interobserver variability. In this study the interobserver agreement amongst five nephropathologists was analysed...
  20. ncbi Removal of heparan sulfate from the glomerular basement membrane blocks protein passage
    Tessa J M Wijnhoven
    Department of Matrix Biochemistry, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Am Soc Nephrol 18:3119-27. 2007
    ..Taken together, these results suggest that HS keeps the GBM in an open state, facilitating passage of proteins through the glomerular capillary wall...
  21. ncbi A synthetic heparanase inhibitor reduces proteinuria in passive Heymann nephritis
    Vicki Levidiotis
    Austin Research Institute, Department of Nephrology, University of Melbourne, Australia
    J Am Soc Nephrol 15:2882-92. 2004
    ..0001) in the absence of altered agrin distribution. These data therefore confirm the importance of heparanase in the development of proteinuria...
  22. ncbi Asymmetry in histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote
    Godfried W van der Heijden
    Department of Obstetrics and Gynaecology, University Medical Centre St Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Mech Dev 122:1008-22. 2005
    ..In summary the male, in contrast to female G1 chromatin, is uniform and contains predominantly histone H3.3 as histone H3 variant...