Harald E Vonkeman

Summary

Affiliation: Medisch Spectrum Twente
Country: The Netherlands

Publications

  1. ncbi Disseminated primary varicella infection during infliximab treatment
    Harald Vonkeman
    Department of Rheumatology and the Department of Internal Medicine, Medisch Spectrum Twente, PO Box 50000, 7500 KA Enschede, The Netherlands
    J Rheumatol 31:2517-8. 2004
  2. ncbi Understanding the NSAID related risk of vascular events
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital and University of Twente, Enschede, Netherlands
    BMJ 332:895-8. 2006
  3. ncbi Direct medical costs of serious gastrointestinal ulcers among users of NSAIDs
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital, and University of Twente, Enschede, The Netherlands
    Drugs Aging 24:681-90. 2007
  4. ncbi Allele variants of the cytochrome P450 2C9 genotype in white subjects from The Netherlands with serious gastroduodenal ulcers attributable to the use of NSAIDs
    Harald E Vonkeman
    Department of Rheumatolog and Clinical Immunoloy, Medisch Spectrum Twente Hospital, University of Twente, Enschede, The Netherlands
    Clin Ther 28:1670-6. 2006
  5. ncbi Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital and University of Twente, Ariensplein 1, 7500 KA, Enschede, The Netherlands
    Arthritis Res Ther 9:R52. 2007
  6. ncbi Under-utilization of gastroprotective drugs in patients with NSAID-related ulcers
    H E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital and University of Twente, 2Stroinkslanden Pharmacy, Enschede, The Netherlands
    Int J Clin Pharmacol Ther 45:281-8. 2007
  7. ncbi Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital Group and University of Twente, Enschede, The Netherlands
    Semin Arthritis Rheum 39:294-312. 2010
  8. ncbi Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente and University of Twente, Enschede, The Netherlands
    Arthritis Res Ther 10:R144. 2008
  9. ncbi Eradication of Helicobacter pylori does not reduce the incidence of gastroduodenal ulcers in patients on long-term NSAID treatment: double-blind, randomized, placebo-controlled trial
    Helena T J I de Leest
    Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
    Helicobacter 12:477-85. 2007

Collaborators

Detail Information

Publications9

  1. ncbi Disseminated primary varicella infection during infliximab treatment
    Harald Vonkeman
    Department of Rheumatology and the Department of Internal Medicine, Medisch Spectrum Twente, PO Box 50000, 7500 KA Enschede, The Netherlands
    J Rheumatol 31:2517-8. 2004
    ..A young man developed a serious disseminated varicella infection, necessitating antiviral treatment, after being treated with anti-tumor necrosis factor-alpha therapy for rheumatoid arthritis...
  2. ncbi Understanding the NSAID related risk of vascular events
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital and University of Twente, Enschede, Netherlands
    BMJ 332:895-8. 2006
  3. ncbi Direct medical costs of serious gastrointestinal ulcers among users of NSAIDs
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital, and University of Twente, Enschede, The Netherlands
    Drugs Aging 24:681-90. 2007
    ..The occurrence and prevention of gastrointestinal ulcers during use of NSAIDs has become a major healthcare issue...
  4. ncbi Allele variants of the cytochrome P450 2C9 genotype in white subjects from The Netherlands with serious gastroduodenal ulcers attributable to the use of NSAIDs
    Harald E Vonkeman
    Department of Rheumatolog and Clinical Immunoloy, Medisch Spectrum Twente Hospital, University of Twente, Enschede, The Netherlands
    Clin Ther 28:1670-6. 2006
    ..These AEs are dose related, and reduced oral clearance of NSAIDs associated with polymorphisms of cytochrome P450 (CYP) would, theoretically, increase the risk for AEs...
  5. ncbi Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital and University of Twente, Ariensplein 1, 7500 KA, Enschede, The Netherlands
    Arthritis Res Ther 9:R52. 2007
    ..17 to 0.67; p = 0.002). Especially at risk for NSAID ulcer complications are elderly patients with cardiovascular co-morbidity. Proton-pump inhibitors are associated with a reduced risk for NSAID ulcer complications...
  6. ncbi Under-utilization of gastroprotective drugs in patients with NSAID-related ulcers
    H E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital and University of Twente, 2Stroinkslanden Pharmacy, Enschede, The Netherlands
    Int J Clin Pharmacol Ther 45:281-8. 2007
    ..To determine the proportion of patients with a risk of NSAID gastropathy receiving adequate gastroprotection...
  7. ncbi Nonsteroidal anti-inflammatory drugs: adverse effects and their prevention
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente Hospital Group and University of Twente, Enschede, The Netherlands
    Semin Arthritis Rheum 39:294-312. 2010
    ..To discuss nonsteroidal anti-inflammatory drugs (NSAIDs), their history, development, mode of action, toxicities, strategies for the prevention of toxicity, and future developments...
  8. ncbi Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study
    Harald E Vonkeman
    Department of Rheumatology and Clinical Immunology, Medisch Spectrum Twente and University of Twente, Enschede, The Netherlands
    Arthritis Res Ther 10:R144. 2008
    ..We estimated the cost effectiveness of concomitant proton pump inhibitors (PPIs) in relation to the occurrence of non-steroidal anti-inflammatory drug (NSAID) ulcer complications...
  9. ncbi Eradication of Helicobacter pylori does not reduce the incidence of gastroduodenal ulcers in patients on long-term NSAID treatment: double-blind, randomized, placebo-controlled trial
    Helena T J I de Leest
    Department of Rheumatology, VU University Medical Center, Amsterdam, The Netherlands
    Helicobacter 12:477-85. 2007
    ..Helicobacter pylori and nonsteroidal antiinflammatory drugs (NSAIDs) are the major causes of gastroduodenal ulcers. Studies on the benefit of eradication of H. pylori in NSAID users yielded conflicting results...