E A Joosten

Summary

Affiliation: Maastricht University
Country: The Netherlands

Publications

  1. ncbi Olfactory ensheathing cells, olfactory nerve fibroblasts and biomatrices to promote long-distance axon regrowth and functional recovery in the dorsally hemisected adult rat spinal cord
    R Deumens
    Department of Psychiatry and Neuropsychology, Division Neuroscience, European Graduate School of Neuroscience EURON, University of Maastricht, 6200 MD, Maastricht, The Netherlands
    Exp Neurol 200:89-103. 2006
  2. ncbi Effect of spinal cord stimulation in an animal model of neuropathic pain relates to degree of tactile "allodynia"
    H Smits
    Pain Management and Research Center, Department of Anaesthesiology, Maastricht University Hospital, P. Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Neuroscience 143:541-6. 2006
  3. ncbi Collagen containing neonatal astrocytes stimulates regrowth of injured fibers and promotes modest locomotor recovery after spinal cord injury
    E A J Joosten
    Department of Anesthesiology, Academic Hospital Maastricht, Maastricht, The Netherlands
    J Neurosci Res 77:127-42. 2004
  4. ncbi Cellular changes in motoneurons in a transgenic mouse model for amyotrophic lateral sclerosis as revealed by monoclonal antibody Py
    E A Joosten
    Laboratory of Experimental Neurology, Department of Neurology, Rudolf Magnus Institute for Neurosciences, Utrecht University, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Brain Res Dev Brain Res 131:153-9. 2001
  5. ncbi Local acute application of BDNF in the lesioned spinal cord anti-inflammatory and anti-oxidant effects
    E A J Joosten
    Division of Cellular Neuroscience, Room 1 112, European Graduate School for Neuroscience, Faculty of Medicine, UNS 50, University of Maastricht, 6200 MD Maastricht, The Netherlands
    Neuroreport 15:1163-6. 2004
  6. ncbi Alpha-melanocyte stimulating hormone promotes regrowth of injured axons in the adult rat spinal cord
    E A Joosten
    Department of Neurology, Rudolf Magnus Institute for Neurosciences, University of Utrecht, The Netherlands
    J Neurotrauma 16:543-53. 1999
  7. ncbi Collagen IV deposits do not prevent regrowing axons from penetrating the lesion site in spinal cord injury
    E A Joosten
    Department of Neurology, Rudolf Magnus Institute for Neurosciences, Utrecht, The Netherlands
    J Neurosci Res 62:686-91. 2000
  8. ncbi Up-regulation of CD81 (target of the antiproliferative antibody; TAPA) by reactive microglia and astrocytes after spinal cord injury in the rat
    S Dijkstra
    Department of Experimental Neurology, RMI for Neurosciences, University Medical Centre, 3508 GA Utrecht, The Netherlands
    J Comp Neurol 428:266-77. 2000
  9. ncbi Differential cortico-motoneuron vulnerability after chronic mitochondrial inhibition in vitro and the role of glutamate receptors
    M G Van Westerlaak
    Department of Experimental Neurology, Room G02 320, RMI for Neurosciences, UMC Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    Brain Res 922:243-9. 2001
  10. ncbi Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: the role of KCC2 and GABA(A) receptor-mediated inhibition
    S P Janssen
    Pain Management and Research Center, Department of Anesthesiology, Maastricht University Medical Center, P Debyelaan 25, P O Box 5800, 6202 AZ Maastricht, The Netherlands
    Neurochem Int 60:21-30. 2012

Collaborators

Detail Information

Publications21

  1. ncbi Olfactory ensheathing cells, olfactory nerve fibroblasts and biomatrices to promote long-distance axon regrowth and functional recovery in the dorsally hemisected adult rat spinal cord
    R Deumens
    Department of Psychiatry and Neuropsychology, Division Neuroscience, European Graduate School of Neuroscience EURON, University of Maastricht, 6200 MD, Maastricht, The Netherlands
    Exp Neurol 200:89-103. 2006
    ..Although multifactorial strategies may be needed to stimulate repair of large spinal lesion gaps, we conclude that the combined use of OEC/ONF and poly(D,L)-lactide biomatrices is rather limited...
  2. ncbi Effect of spinal cord stimulation in an animal model of neuropathic pain relates to degree of tactile "allodynia"
    H Smits
    Pain Management and Research Center, Department of Anaesthesiology, Maastricht University Hospital, P. Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Neuroscience 143:541-6. 2006
    ....
  3. ncbi Collagen containing neonatal astrocytes stimulates regrowth of injured fibers and promotes modest locomotor recovery after spinal cord injury
    E A J Joosten
    Department of Anesthesiology, Academic Hospital Maastricht, Maastricht, The Netherlands
    J Neurosci Res 77:127-42. 2004
    ..The implantation of neonatal astroglial cells did result in modest temporary improvements of locomotor recovery as observed during open-field locomotion analysis (BBB subscore) or during crossing of a walkway (catwalk)...
  4. ncbi Cellular changes in motoneurons in a transgenic mouse model for amyotrophic lateral sclerosis as revealed by monoclonal antibody Py
    E A Joosten
    Laboratory of Experimental Neurology, Department of Neurology, Rudolf Magnus Institute for Neurosciences, Utrecht University, P O Box 85500, 3508 GA Utrecht, The Netherlands
    Brain Res Dev Brain Res 131:153-9. 2001
    ..It is concluded that the Py-antibody detects early intracellular abnormalities related to neurodegenerative changes in spinal motoneurons of transgenic SOD1-(G93A) mice...
  5. ncbi Local acute application of BDNF in the lesioned spinal cord anti-inflammatory and anti-oxidant effects
    E A J Joosten
    Division of Cellular Neuroscience, Room 1 112, European Graduate School for Neuroscience, Faculty of Medicine, UNS 50, University of Maastricht, 6200 MD Maastricht, The Netherlands
    Neuroreport 15:1163-6. 2004
    ..The early anti-inflammatory and anti-oxidant effects of local BDNF-application into the lesioned spinal cord may contribute to the observed decreased loss of locomotor function of the hindlimbs 2 days after injury...
  6. ncbi Alpha-melanocyte stimulating hormone promotes regrowth of injured axons in the adult rat spinal cord
    E A Joosten
    Department of Neurology, Rudolf Magnus Institute for Neurosciences, University of Utrecht, The Netherlands
    J Neurotrauma 16:543-53. 1999
    ..In conclusion, inclusion of alpha-MSH in the collagen implant stimulates the regrowth of injured axons in the adult rat spinal cord...
  7. ncbi Collagen IV deposits do not prevent regrowing axons from penetrating the lesion site in spinal cord injury
    E A Joosten
    Department of Neurology, Rudolf Magnus Institute for Neurosciences, Utrecht, The Netherlands
    J Neurosci Res 62:686-91. 2000
    ..In conclusion, our observations indicate that collagen IV deposits after spinal cord injury do not prevent neurofilament-positive regrowing axons from penetrating the lesion site...
  8. ncbi Up-regulation of CD81 (target of the antiproliferative antibody; TAPA) by reactive microglia and astrocytes after spinal cord injury in the rat
    S Dijkstra
    Department of Experimental Neurology, RMI for Neurosciences, University Medical Centre, 3508 GA Utrecht, The Netherlands
    J Comp Neurol 428:266-77. 2000
    ..In conclusion, the spatiotemporal expression pattern of CD81 by reactive microglia and astrocytes indicates that CD81 is involved in the glial response to spinal cord injury...
  9. ncbi Differential cortico-motoneuron vulnerability after chronic mitochondrial inhibition in vitro and the role of glutamate receptors
    M G Van Westerlaak
    Department of Experimental Neurology, Room G02 320, RMI for Neurosciences, UMC Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    Brain Res 922:243-9. 2001
    ..The present investigation gives insight in mechanisms leading to excitotoxic cell death of CMNs and may therefore be important for the development of treatment strategies in protection and survival of cortical motoneurons in ALS...
  10. ncbi Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: the role of KCC2 and GABA(A) receptor-mediated inhibition
    S P Janssen
    Pain Management and Research Center, Department of Anesthesiology, Maastricht University Medical Center, P Debyelaan 25, P O Box 5800, 6202 AZ Maastricht, The Netherlands
    Neurochem Int 60:21-30. 2012
    ..Furthermore, a KCC2-dependent impaired GABA(A) receptor-mediated inhibition seems to be present both in responders and non-responders to SCS due to similar KCC2 and GABA(A) receptor levels...
  11. ncbi Axon guidance of outgrowing corticospinal fibres in the rat
    E A Joosten
    Department of Neurology, Laboratory of Experimental Neurology, Academic Hospital Utrecht, The Netherlands
    J Anat 194:15-32. 1999
    ..In this respect the corticospinal tract forms an important example and model system for the better understanding of central nervous system development in general...
  12. ncbi CD81 and microglial activation in vitro: proliferation, phagocytosis and nitric oxide production
    S Dijkstra
    Department of Experimental Neurology, UMC Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    J Neuroimmunol 114:151-9. 2001
    ..The phagocytosis of latex beads, as well as the production of nitric oxide, were not significantly influenced by AMP1. These data indicate that CD81 is involved in an important subset of microglial effector functions after CNS injury...
  13. ncbi Differential GABAergic disinhibition during the development of painful peripheral neuropathy
    S P Janssen
    Pain Management and Research Center, Department of Anesthesiology, Maastricht University Medical Center, P Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Neuroscience 184:183-94. 2011
    ....
  14. ncbi Spinal cord stimulation of dorsal columns in a rat model of neuropathic pain: evidence for a segmental spinal mechanism of pain relief
    H Smits
    Pain Management and Research Center, Department of Anesthesiology, Maastricht University Hospital, Maastricht, The Netherlands
    Pain 153:177-83. 2012
    ..From this we conclude that SCS in treatment of neuropathic pain acts through a segmental spinal site of action...
  15. ncbi Systemic but not local administration of retinoic acid reduces early transcript levels of pro-inflammatory cytokines after experimental spinal cord injury
    S van Neerven
    Department of Anesthesiology, School for Mental Health and Neuroscience, Maastricht University Medical Center, P Debyelaan 25, 6202 AZ, Maastricht, The Netherlands
    Neurosci Lett 485:21-5. 2010
    ..Future studies are required to investigate the effects of single intraperitoneal RA treatment on long-term SCI outcome...
  16. ncbi High frequency stimulation of the subthalamic nucleus improves speed of locomotion but impairs forelimb movement in Parkinsonian rats
    R Vlamings
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Neuroscience 148:815-23. 2007
    ..The static features of gait were only significantly influenced with low amplitude. Remarkably, STN stimulation affected predominantly the forepaws/limbs...
  17. ncbi The CatWalk method: a detailed analysis of behavioral changes after acute inflammatory pain in the rat
    A F Gabriel
    Department of Anesthesiology, Academic Hospital Maastricht, 6200 MD Maastricht, The Netherlands
    J Neurosci Methods 163:9-16. 2007
    ..In conclusion, the CatWalk method allows an objective and detailed detection of both pain-induced gait adaptations as well as the development of mechanical allodynia in an acute inflammatory pain model...
  18. ncbi Intraspinal administration of an antibody against CD81 enhances functional recovery and tissue sparing after experimental spinal cord injury
    S Dijkstra
    Department of Experimental Neurology, Rudolf Magnus Institute for Neuroscience, University Medical Center Utrecht, The Netherlands
    Exp Neurol 202:57-66. 2006
    ..Our data demonstrate beneficial effects of an anti-CD81 antibody on functional recovery in spinal cord injured rats and suggest that this effect is mediated through a reduction in secondary tissue loss...
  19. ncbi Chronically injured corticospinal axons do not cross large spinal lesion gaps after a multifactorial transplantation strategy using olfactory ensheathing cell/olfactory nerve fibroblast-biomatrix bridges
    R Deumens
    Department of Psychiatry and Neuropsychology, Division Neuroscience, European Graduate School of Neuroscience EURON, University of Maastricht, Maastricht, The Netherlands
    J Neurosci Res 83:811-20. 2006
    ..We conclude that our multifactorial transplantation strategy should be optimized to create an OEC/ONF continuum in the injured spinal cord and thereby stimulate regrowth of injured CS axons across large spinal lesion gaps...
  20. ncbi Sexual differences in onset of disease and response to exercise in a transgenic model of ALS
    J H Veldink
    Department of Neurology, G.03.228 University Medical Center Utrecht, P.O. Box 85500, 3508 GA, Utrecht, Netherlands
    Neuromuscul Disord 13:737-43. 2003
    ..These results suggest a possible neuroprotective effect of female sex hormones and support the view that ALS patients should not avoid regular exercise...
  21. ncbi Alignment of glial cells stimulates directional neurite growth of CNS neurons in vitro
    R Deumens
    Department of Psychiatry and Neuropsychology, European Graduate School for Neuroscience EURON, Universiteit Maastricht, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Neuroscience 125:591-604. 2004
    ..These data have significant implications for in vivo experiments focusing on glial transplantation. Transplanting glial/biomatrix complexes may stimulate the directional regrowth of severed axons across a lesion site...