Matthew S Hestand

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. ncbi CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated genes
    Matthew S Hestand
    The Center for Human and Clinical Genetics, Leiden University Medical Center, Postzone S4 0P, PO Box 9600, 2300 RC Leiden, The Netherlands
    BMC Bioinformatics 9:495. 2008
  2. ncbi Genome-wide assessment of differential roles for p300 and CBP in transcription regulation
    Yolande F M Ramos
    Department of Molecular Cell Biology, Leiden University Medical Center, Postzone S4 0P, PO Box 9600, 2300 RC Leiden, The Netherlands
    Nucleic Acids Res 38:5396-408. 2010
  3. ncbi Tissue-specific transcript annotation and expression profiling with complementary next-generation sequencing technologies
    Matthew S Hestand
    The Center for Human and Clinical Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Nucleic Acids Res 38:e165. 2010

Detail Information

Publications3

  1. ncbi CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated genes
    Matthew S Hestand
    The Center for Human and Clinical Genetics, Leiden University Medical Center, Postzone S4 0P, PO Box 9600, 2300 RC Leiden, The Netherlands
    BMC Bioinformatics 9:495. 2008
    ..Computational methods to reduce false positives are to look for over-representation of transcription factor binding sites in a set of similarly regulated promoters or to look for conservation in orthologous promoter alignments...
  2. ncbi Genome-wide assessment of differential roles for p300 and CBP in transcription regulation
    Yolande F M Ramos
    Department of Molecular Cell Biology, Leiden University Medical Center, Postzone S4 0P, PO Box 9600, 2300 RC Leiden, The Netherlands
    Nucleic Acids Res 38:5396-408. 2010
    ..Taken together, our findings further elucidate the distinct roles of coactivators p300 and CBP in transcriptional regulation...
  3. ncbi Tissue-specific transcript annotation and expression profiling with complementary next-generation sequencing technologies
    Matthew S Hestand
    The Center for Human and Clinical Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
    Nucleic Acids Res 38:e165. 2010
    ..Next-generation sequencing of CAGE and SAGE libraries provides consistent expression levels and can enrich current genome annotations with tissue-specific promoters and alternative 3'-UTR usage...