Research Topics
Species | Bart EvertsSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Combined TLR2 and TLR4 ligation in the context of bacterial or helminth extracts in human monocyte derived dendritic cells: molecular correlates for Th1/Th2 polarizationElly van Riet
Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands
BMC Immunol 10:9. 2009....
Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responsesBart Everts
Department of Parasitology, Leiden University Medical Centre, ZA Leiden, The Netherlands
Eur J Immunol 40:1525-37. 2010..Here, we will discuss these new insights and will link them to the origin and importance of Th2 and regulatory immune responses with respect to the survival of both parasite and host...
Functional impairment of human myeloid dendritic cells during Schistosoma haematobium infectionBart Everts
Department of Parasitology, Leiden University Medical Centre, Leiden, The Netherlands
PLoS Negl Trop Dis 4:e667. 2010..haematobium infection is associated with functional impairment of human DC function in vivo and provide new insights into the underlying mechanisms of T cell hyporesponsiveness during chronic schistosomiasis...
Chronic helminth infections protect against allergic diseases by active regulatory processesHermelijn H Smits
Department of Parasitology, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands
Curr Allergy Asthma Rep 10:3-12. 2010..It is of great interest to define and characterize specific helminth molecules that have profound immunomodulatory capacities as targets for therapeutic application in the treatment or prophylaxis of allergic manifestations...
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responsesBart Everts
Department of Parasitology, Leiden University Medical Centre, Leiden 2333 ZA, The Netherlands
J Exp Med 206:1673-80. 2009..Collectively, we identify omega-1, a single component of SEA, as a potent inducer of Th2 responses...
