Research Topics
| R J Baatenburg de JongSummaryAffiliation: Leiden University Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Chondroma and chondrosarcoma of the larynxRobert J Baatenburg de Jong
Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Holland
Curr Opin Otolaryngol Head Neck Surg 12:98-105. 2004..The purpose of this review is to give a detailed description of chondroma and chondrosarcoma of the larynx and to put into perspective new findings from recent literature...
Prediction of survival in patients with head and neck cancerR J Baatenburg de Jong
Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, P O Box 9600, 2300RC Leiden, Holland
Head Neck 23:718-24. 2001..With these hospital-based data, we developed a statistical model for risk assessment and prediction of overall survival. This model serves in clinical decision making and appropriate counseling of patients with HNSCC...
A new surgical technique for treatment of preauricular sinusRobert J Baatenburg de Jong
Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, The Netherlands
Surgery 137:567-70. 2005..Surgical treatment of PAS is characterized by high recurrence rates. This paper describes a single institution's experience with the operative management of PAS and introduces a new technique...
Bcl-xL inhibits p53- but not apoptin-induced apoptosis in head and neck squamous cell carcinoma cell lineRemilio A L Schoop
Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Int J Cancer 109:38-42. 2004..Our data demonstrate that apoptin induces apoptosis independent of Bcl-x(L) and p53 and may constitute a potential therapeutic agent for treatment of HNSCC...
Clinical outcome of T1 glottic carcinoma since the introduction of endoscopic CO2 laser surgery as treatment optionElisabeth V Sjögren
Department of ENT, Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Head Neck 30:1167-74. 2008..Since the introduction of endoscopic laser surgery at our institution in 1996, 189 patients have been treated for T1 glottic carcinoma...
Gene-expression of metastasized versus non-metastasized primary head and neck squamous cell carcinomas: a pathway-based analysisErik F Hensen
Department of Otolaryngology and Head and Neck Surgery, Leiden University, Medical Centre, Leiden, The Netherlands
BMC Cancer 8:168. 2008..Here, we present an independent gene expression validation study of metastasized versus non-metastasized HNSCC...
Apoptin induces apoptosis in an oral cancer mouse modelRemilio A L Schoop
Department of Otolaryngology, Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Cancer Biol Ther 7:1368-73. 2008..The fact that apoptin induces apoptosis in primary squamous cell carcinoma cells indicates that apoptin is a potential therapeutic agent for treatment of head and neck squamous cell carcinoma...
Voice outcome in T1a midcord glottic carcinoma: laser surgery vs radiotherapyElisabeth V Sjögren
Department of ENT Head and Neck Surgery, Leiden University Medical Center, Floor J6 166, Albinusdreef 2, Postbus 9600, 2300 RC Leiden, The Netherlands
Arch Otolaryngol Head Neck Surg 134:965-72. 2008..To compare voice quality after radiotherapy or endoscopic laser surgery in patients with similar T1a midcord glottic carcinomas according to a validated multidimensional protocol...
Quality of life and illness perceptions in patients with recently diagnosed head and neck cancerMargreet Scharloo
Psychology Unit, Leiden University Medical Center, PO Box 9555, 2300 RB Leiden, The Netherlands
Head Neck 27:857-63. 2005....
Voice profile after type I or II laser chordectomies for T1a glottic carcinomaElisabeth V Sjögren
Department of ENT, Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Head Neck 31:1502-10. 2009..Can a "typical" voice in terms of auditory perception be defined after type I or II chordectomy? Do other parameters in a multidimensional voice protocol correlate to this perceptual profile?..
A mouse model for oral squamous cell carcinomaRemilio A L Schoop
Department of Otolaryngology and Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
J Mol Histol 40:177-81. 2009..Future survey of therapeutic options in the carcinogenic 4NQO model should be conducted around 40 weeks after the start of the treatment...
DNA ploidy status as a prognostic marker and predictor of lymph node metastasis in laryngeal carcinomaRobert P Takes
Department of Otorhinolaryngology-Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Ann Otol Rhinol Laryngol 111:1015-20. 2002..The DNA ploidy status may be a useful marker for metastatic behavior in head and neck squamous cell carcinoma and may therefore be helpful in decision-making concerning elective treatment of the neck...
Illness cognitions in head and neck squamous cell carcinoma: predicting quality of life outcomeMargreet Scharloo
Medical Psychology, Leiden University Medical Center, 2300 RB Leiden, The Netherlands
Support Care Cancer 18:1137-45. 2010....
Expression of genetic markers in lymph node metastases compared with their primary tumours in head and neck cancerR P Takes
Department of Otolaryngology, Leiden University Medical Center, Leiden, The Netherlands
J Pathol 194:298-302. 2001..This also implies differences in the regulation of markers involved in tumourigenesis and the process of metastasis...
Influence of previous tumours on survival in early (Tis-T1) glottic carcinomaElisabeth V Sjögren
Department of Otolaryngology, Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
J Otolaryngol Head Neck Surg 38:449-55. 2009..To investigate the influence of previous tumours on overall survival in patients with early glottic carcinoma...
Apoptin enhances radiation-induced cell death in poorly responding head and neck squamous cell carcinoma cellsRemilio A L Schoop
Department of Otolaryngology, Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Basic Clin Pharmacol Toxicol 106:130-4. 2010..Our data reveal that apoptin treatment represents an effective way for enhancing radiotherapy of tumours responding poorly to radiotherapy...
Evaluation of voice quality in adductor spasmodic dysphonia before and after botulinum toxin treatmentT P Langeveld
Department of Otorhinolaryngology-Head and Neck Surgery, Leiden University Medical Center, The Netherlands
Ann Otol Rhinol Laryngol 110:627-34. 2001..Although significant improvement could be measured in our study perceptually, acoustically, and subjectively, the optimal voice that was achieved never fully matched normal voice quality or function...
HGF and c-MET as potential orchestrators of invasive growth in head and neck squamous cell carcinomaMaria Jantine De Herdt
Department of Otolaryngology and Head and Neck Surgery, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 300 CA Rotterdam, The Netherlands
Front Biosci 13:2516-26. 2008..It is concluded that both molecules are mis- and over-expressed in HNSCC and probably induce the program of invasive growth in HNSCC...
Comorbidity as a major risk factor for mortality and complications in head and neck surgeryMarciano B Ferrier
Department of Otolaryngology Head and Neck Surgery, Leiden University Medical Center, Leiden, The Netherlands
Arch Otolaryngol Head Neck Surg 131:27-32. 2005..To describe the impact of comorbidity on complications of surgery and mortality in patients with head and neck squamous cell carcinoma (HNSCC)...
A visual analog scale can assess the effect of surgical treatment in children with chronic otitis media with effusionFrank R Datema
Department of Otolaryngology, HagaZiekenhuis, Location Juliana Children s Hospital, The Hague, The Netherlands
Int J Pediatr Otorhinolaryngol 72:461-7. 2008..The change in overall OM-6 scores due to surgical treatment, functions as the gold reference standard. Furthermore, this study tests if the VAS is faster to use than the OM-6 and if it leads to an improvement in complete data collection...
Evaluating adherence to the Dutch guideline for diagnosis, treatment and follow-up of laryngeal carcinomasMichel van Agthoven
Department of Health Policy and Management, Institute for Medical Technology Assessment, Erasmus MC, University Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands
Radiother Oncol 74:337-44. 2005..The largest changes were seen for the guideline recommendations based on the highest levels of evidence...
Markers for nodal metastasis in head and neck squamous cell cancerRobert P Takes
Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital, Leiden, The Netherlands
Arch Otolaryngol Head Neck Surg 128:512-8. 2002..To identify markers that are relevant as predictors of lymph node metastasis in head and neck squamous cell cancer...
Compliance and efficiency before and after implementation of a clinical practice guideline for laryngeal carcinomasMichel van Agthoven
Department of Health Policy and Management, Institute for Medical Technology Assessment, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, 3000 DR, Rotterdam, The Netherlands
Eur Arch Otorhinolaryngol 263:729-37. 2006..Balanced against the equal costs before and after the guideline's implementation, we conclude that the efficiency of the care process improved...
