Research Topics
| Martien W BorgdorffSummaryAffiliation: KNCV Tuberculosis Foundation Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
Delays in the diagnosis and treatment of tuberculosis patients in Vietnam: a cross-sectional studyNguyen T Huong
National Hospital of Tuberculosis and Respiratory Diseases, Hanoi, Vietnam
BMC Public Health 7:110. 2007..This study assesses the patient, health care provider and total delay in diagnosis and treatment of new smear-positive pulmonary tuberculosis patients, and the risk factors for long delay, in Vietnam...
Prevalence of tuberculosis drug resistance in 10 provinces of ChinaGuang Xue He
National Center for TB control and prevention, China Center for Disease Control and Prevention CDC, Beijing, PR China
BMC Infect Dis 8:166. 2008..The emergence of drug-resistant tuberculosis (TB) hampers TB control. Ten provinces in China performed drug resistance surveys among tuberculosis (TB) patients in 1996-2004 to assess levels of drug resistance...
Low tuberculosis notification in mountainous Vietnam is not due to low case detection: a cross-sectional surveyM Vree
KNCV Tuberculosis Foundation, The Hague, The Netherlands
BMC Infect Dis 7:109. 2007....
[Research into new methods for diagnosing, treating and preventing tuberculosis]M W Borgdorff
Academisch Medisch Centrum Universiteit van Amsterdam, Amsterdam
Ned Tijdschr Geneeskd 147:1838-41. 2003..However, new candidate vaccines are being developed and will be tested on humans in the near future...
New measurable indicator for tuberculosis case detectionMartien W Borgdorff
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Emerg Infect Dis 10:1523-8. 2004..Conducting prevalence surveys at 5- to 10-year intervals would allow countries with high rates of disease to determine their case detection performance by using the patient diagnostic rate and determine the effect of control measures...
Tuberculosis elimination in the NetherlandsMartien W Borgdorff
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Emerg Infect Dis 11:597-602. 2005..Under current epidemiologic conditions and control efforts, TB may not be eliminated...
Mycobacterium tuberculosis Beijing genotype, the NetherlandsMartien W Borgdorff
Royal Netherlands Tuberculosis Association, PO Box 146, 2501 CC The Hague, The Netherlands
Emerg Infect Dis 9:1310-3. 2003
[Control of drug-sensitive and (multi-)resistant tuberculosis]M W Borgdorff
Koninklijke Nederlandse Centrale Vereniging tot bestrijding der Tuberculose, Postbus 146, 2501 CC Den Haag
Ned Tijdschr Geneeskd 146:1525-7. 2002..Important problems remain with respect to the feasibility and costs of these measures and the prevention of additional resistance...
Interventions to reduce tuberculosis mortality and transmission in low- and middle-income countriesMartien W Borgdorff
Royal Netherlands Tuberculosis Association, The Hague, The Netherlands
Bull World Health Organ 80:217-27. 2002....
Transmission of Mycobacterium tuberculosis depending on the age and sex of source casesM W Borgdorff
Royal Netherlands Tuberculosis Association, The Hague, The Netherlands
Am J Epidemiol 154:934-43. 2001..Increased transmission among immigrant groups in the Netherlands is largely attributable to the relatively young age of immigrant source cases...
Mycobacterium tuberculosis, Beijing genotype strains not associated with radiological presentation of pulmonary tuberculosisMartien W Borgdorff
KNCV Tuberculosis Foundation, The Hague, Netherlands
Tuberculosis (Edinb) 84:337-40. 2004..No significant differences were detected. We conclude that the Beijing genotype is not associated with a different CXR presentation...
High mortality during tuberculosis treatment does not indicate long diagnostic delays in Vietnam: a cohort studyMarleen Vree
Research Unit, KNCV Tuberculosis Foundation, The Hague, The Netherlands
BMC Public Health 7:210. 2007..However, data for this presumed association between delay and fatality are lacking. We assessed the association between diagnostic delay and mortality of new smear-positive pulmonary tuberculosis patients in Vietnam...
Targets for tuberculosis control: how confident can we be about the data?Marieke J van der Werf
KNCV Tuberculosis Foundation, The Hague, Netherlands
Bull World Health Organ 85:370-6. 2007..Routine surveillance and vital registration systems need to be strengthened. We recommend that national TB prevalence surveys be performed in selected high-burden countries, in Africa in particular...
Tuberculosis outbreaks predicted by characteristics of first patients in a DNA fingerprint clusterSandra V Kik
KNCV Tuberculosis Foundation, PO Box 146, 2501 CC The Hague, The Netherlands
Am J Respir Crit Care Med 178:96-104. 2008..Some clusters of patients who have Mycobacterium tuberculosis isolates with identical DNA fingerprint patterns grow faster than others. It is unclear what predictors determine cluster growth...
The incubation period distribution of tuberculosis estimated with a molecular epidemiological approachMartien W Borgdorff
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Int J Epidemiol 40:964-70. 2011..There is limited information on the distribution of incubation periods of tuberculosis (TB)...
Extrapulmonary tuberculosis by nationality, The Netherlands, 1993-2001Lowieke A M te Beek
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Emerg Infect Dis 12:1375-82. 2006..The growth of the number of inhabitants with a non-Western ethnic background in the Netherlands explains the proportional growth of extrapulmonary TB. Physicians need to be aware of the changing clinical picture of TB...
Mortality and failure among tuberculosis patients who did not complete treatment in Vietnam: a cohort studyMarleen Vree
KNCV Tuberculosis Foundation, The Hague, The Netherlands
BMC Public Health 7:134. 2007..Treatment outcomes rates were 1.4% default, 3.0% transfer-out, 0.4% failure and 2.6% death in northern Vietnam in 2003...
Evaluating tuberculosis case detection in EritreaMarieke J van der Werf
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Emerg Infect Dis 13:1497-9. 2007..The CDR obtained from the survey was approximately 40%, whereas the CDR published by the World Health Organization was 3x lower (14%)...
Logistic discrimination of mixtures of M. tuberculosis and non-specific tuberculin reactionsN J Nagelkerke
Royal Netherlands Tuberculosis Association (KNCV, The Hague, The Netherlands
Stat Med 20:1113-24. 2001..The proposed method of mixture analysis provides an additional tool for the interpretation of prevalence survey data where the diagnostic test lacks specificity as a result of cross-reactions...
How to measure the prevalence of tuberculosis in a populationMarieke J van der Werf
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Trop Med Int Health 12:475-84. 2007..Most surveys use comparable strategies. Alternatives strategies at lower cost need to be evaluated...
Screening for pulmonary tuberculosis among immigrants: estimated effect on severity of disease and duration of infectiousnessS Verver
Royal Netherlands Tuberculosis Association, The Hague
Int J Tuberc Lung Dis 5:419-25. 2001..CONCLUSION: The screening programme detected cases earlier, resulting in fewer hospital admissions, shorter duration of symptoms and therefore probably reduced tuberculosis transmission...
Association between passive smoking and infection with Mycobacterium tuberculosis in childrenSaskia den Boon
Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
Pediatrics 119:734-9. 2007..The association between passive smoking and Mycobacterium tuberculosis infection is not well documented. The objective of this study was to examine the influence of passive smoking on M. tuberculosis infection in children...
Rate of reinfection tuberculosis after successful treatment is higher than rate of new tuberculosisSuzanne Verver
Desmond Tutu TB Center, Department of Pediatrics and Child Health, Stellenbosch University, Cape Town, South Africa
Am J Respir Crit Care Med 171:1430-5. 2005..In a high-tuberculosis (TB) incidence area of Cape Town, South Africa, there is a very high rate of unexplained recurrent TB. The incidence of new bacteriologically confirmed disease in the area is 313 per 100,000 individuals...
High prevalence of tuberculosis in previously treated patients, Cape Town, South AfricaSaskia den Boon
Desmond Tutu Centre, Stellenbosch University, Cape Town, South Africa
Emerg Infect Dis 13:1189-94. 2007..Such patients may contribute to transmission of Mycobacterium tuberculosis and the high TB prevalence rate. Successful treatment of TB patients must be a priority...
Proportion of tuberculosis transmission that takes place in households in a high-incidence areaSuzanne Verver
Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa
Lancet 363:212-4. 2004..The proportion of transmission in the community that took place in the household was 19%, and therefore, in this high-incidence area, tuberculosis transmission occurs mainly outside the household...
Transmission of tuberculosis in a high incidence urban community in South AfricaSuzanne Verver
Department of Paediatrics and Child Health, Stellenbosch University, South Africa
Int J Epidemiol 33:351-7. 2004..The objective of this study was to identify risk factors for ongoing community transmission of tuberculosis (TB) in two densely populated urban communities with a high incidence rate of TB in Cape Town, South Africa...
TB-HIV co-infection in EritreaM J van der Werf
KNCV Tuberculosis Foundation, P O Box 146, 2501 CC The Hague, The Netherlands
Int J Tuberc Lung Dis 11:823-6. 2007..8%, 95%CI 7.6-16.1) were HIV-infected. Risk factors were age, urban residence and schooling level. The data indicate that, starting with the urban areas, it is time for Eritrea to introduce HIV testing of all TB patients...
The epidemiology of tuberculosis among asylum seekers in The Netherlands: implications for screeningJ L van Burg
Department of Health, Agency for the Reception of Asylum Seekers (COA, The Hague, The Netherlands
Int J Tuberc Lung Dis 7:139-44. 2003....
Effect of screening of immigrants on tuberculosis transmissionS Verver
Royal Netherlands Tuberculosis Association KNCV, The Hague
Int J Tuberc Lung Dis 6:121-9. 2002..In The Netherlands all immigrants from highly endemic countries undergo obligatory entry screening by X-ray, followed by voluntary half-yearly screening for 2 years...
Density of tuberculin skin reaction and its association with tuberculosis infection as defined by dual tuberculin testingM W Borgdorff
Royal Netherlands Tuberculosis Association KNCV and International Tuberculosis Surveillance Centre, The Hague, The Netherlands
Int J Tuberc Lung Dis 4:1060-5. 2000..To determine whether the density of tuberculin skin reactions is associated with tuberculosis infection...
Prevalence of tuberculous infection and incidence of tuberculosis: a re-assessment of the Styblo ruleF van Leth
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Bull World Health Organ 86:20-6. 2008....
The design of multi-stage tuberculin surveys: some suggestions for samplingN J Nagelkerke
Royal Netherlands Tuberculosis Association KNCV, The Hague
Int J Tuberc Lung Dis 4:314-20. 2000..Tuberculin surveys of children to estimate national or regional infection prevalences are commonly designed as multi-stage surveys. These surveys require strategies for the efficient sampling of sub-units at each stage...
Coverage and yield of entry and follow-up screening for tuberculosis among new immigrantsC Erkens
KNCV Tuberculosis Foundation, P O Box 146, 2501 CC The Hague, The Netherlands
Eur Respir J 32:153-61. 2008..Overall coverage and yield of follow-up screening was low. Follow-up screening of immigrants with a normal chest radiograph from countries with an incidence of <200 per 100,000 individuals was therefore discontinued...
Transmission of tuberculosis in San Francisco and its association with immigration and ethnicityM W Borgdorff
Royal Netherlands Tuberculosis Association, The Hague
Int J Tuberc Lung Dis 4:287-94. 2000..To determine tuberculosis transmission dynamics in San Francisco and its association with country of birth and ethnicity...
[Estimation of the incidence of tuberculosis in The Netherlands in 2030]F van Leth
KNCV Tuberculosefonds, Parkstraat 17, 2514 JD Den Haag
Ned Tijdschr Geneeskd 152:616-21. 2008..To estimate the number of cases of tuberculosis (TB) in 2030 for the purpose of planning future TB control...
How to identify tuberculosis cases in a prevalence surveyM J van der Werf
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Int J Tuberc Lung Dis 12:1255-60. 2008..Case definitions are ideally based on the combined results of symptom enquiry, CXR and bacteriology...
Tuberculosis screening among immigrants in The Netherlands: what is its contribution to public health?R Bwire
Royal Netherlands Tuberculosis Association KNCV, Den Haag, The Netherlands
Neth J Med 56:63-71. 2000..The article recommends the setting-up of an information system to evaluate the effectiveness of screening immigrants in The Netherlands, and adjustment of screening policies where needed...
Interferon-gamma release assays in immigrant contacts and effect of remote exposure to Mycobacterium tuberculosisS V Kik
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Int J Tuberc Lung Dis 13:820-8. 2009..TB-in immigrant contacts of sputum smear-positive TB patients...
Predictive value for progression to tuberculosis by IGRA and TST in immigrant contactsS V Kik
KNCV Tuberculosis Foundation, PO Box 146, 2501 CC, The Hague, The Netherlands
Eur Respir J 35:1346-53. 2010..3% (95% CI 1.3-5.3%) for T-SPOT.TB. Sensitivity was 100%, 88%, 63% and 75%, respectively. The predictive values of QFT-GIT, T-SPOT.TB and TST for progression to TB disease among immigrant close contacts were comparable...
Gender and tuberculosis: a comparison of prevalence surveys with notification data to explore sex differences in case detectionM W Borgdorff
Royal Netherlands Tuberculosis Association, The Hague, The Netherlands
Int J Tuberc Lung Dis 4:123-32. 2000..To explore whether lower tuberculosis notification rates among women are due to a reduced access to health care, particularly diagnostic services, for women...
Transmission of tuberculosis between people of different ages in The Netherlands: an analysis using DNA fingerprintingM W Borgdorff
Royal Netherlands Tuberculosis Association KNCV, The Hague
Int J Tuberc Lung Dis 3:202-6. 1999..This study aimed at determining whether this might be explained by preferential transmission within age groups...
Survival and relapse rate of tuberculosis patients who successfully completed treatment in VietnamM Vree
KNCV Tuberculosis Foundation, 3501 CC The Hague, The Netherlands
Int J Tuberc Lung Dis 11:392-7. 2007..Reported tuberculosis (TB) cure rates are high in Vietnam with the 8-month short-course chemotherapy regimen. However, long-term treatment outcomes are unknown...
Tuberculosis infection in children who are contacts of immigrant tuberculosis patientsS Verver
KNCV Tuberculosis Foundation, Parkstraat 17, 2514 JD, The Hague, The Netherlands
Eur Respir J 26:126-32. 2005..In conclusion, the prevalence of active tuberculosis and latent tuberculosis infection among children who are close contacts of immigrant tuberculosis patients is high and warrants an expansion of contact investigation...
An evaluation of symptom and chest radiographic screening in tuberculosis prevalence surveysS den Boon
Desmond Tutu TB Centre, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa
Int J Tuberc Lung Dis 10:876-82. 2006..The population was 36,334 in 2001, and the TB notification rate was 341 per 100,000 population for new smear-positive TB in 2002...
Natural history of tuberculosis: duration and fatality of untreated pulmonary tuberculosis in HIV negative patients: a systematic reviewEdine W Tiemersma
KNCV Tuberculosis Foundation, The Hague, The Netherlands
PLoS ONE 6:e17601. 2011..Furthermore, duration and case fatality of tuberculosis are key parameters in interpreting epidemiological data...
Finding patients eligible for antiretroviral therapy using TB services as entry point for HIV treatmentRobert Bwire
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Trop Med Int Health 11:1567-75. 2006..To estimate the proportion of antiretroviral therapy (ART) eligible adults (15-49 years) with tuberculosis potentially identifiable through tuberculosis services using a CD4 count below 350 cells/mm3 as cut-off value for ART initiation...
Diagnosis and treatment of tuberculosis in the private sector, VietnamNguyen B Hoa
National Tuberculosis Program, Hanoi, Vietnam N B Hoa, D N Sy, N V Nhung Academic Medical Center, Amsterdam, the Netherlands F G J Cobelens, M W Borgdorff, E W Tiemersma Municipal Health Service, Amsterdam M W Borgdorff and KNCV Tuberculosis Foundation, The Hague, the Netherlands E W Tiemersma
Emerg Infect Dis 17:562-4. 2011..However, this estimate does not reflect private care in the entire country...
Public health impact of isoniazid-resistant Mycobacterium tuberculosis strains with a mutation at amino-acid position 315 of katG: a decade of experience in The NetherlandsH R van Doorn
Department of Medical Microbiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Clin Microbiol Infect 12:769-75. 2006..Delta315 isolates were high-level isoniazid-resistant, streptomycin-resistant and multidrug-resistant significantly more often, and may have a greater impact on public health, than other isoniazid-resistant isolates...
Tuberculin skin testing in patients with HIV infection: limited benefit of reduced cutoff valuesFrank G Cobelens
KNCV Tuberculosis Foundation, The Hague, The Netherlands
Clin Infect Dis 43:634-9. 2006..No published studies have assessed this directly in patients with tuberculosis...
The impact of the HIV epidemic on tuberculosis transmission in TanzaniaSaidi M Egwaga
National Tuberculosis and Leprosy Programme, Ministry of Health, Dar es Salaam, Tanzania
AIDS 20:915-21. 2006..This suggests that in the presence of a strong control programme, the HIV epidemic has limited impact on tuberculosis transmission...
Prospects for advancing tuberculosis control efforts through novel therapiesJoshua A Salomon
Department of Population and International Health, Harvard School of Public Health, Boston, Massachusetts, United States of America
PLoS Med 3:e273. 2006..As new candidates emerge from the global TB drug pipeline, the potential impacts of novel, shorter regimens on TB incidence and mortality have not yet been examined...
Impact of HIV on novel therapies for tuberculosis controlMaria S Sanchez
Department of Environmental Science, Policy and Management, University of California, Berkeley, California 94720 3114, USA
AIDS 22:963-72. 2008..We investigated how tuberculosis is impacted by reducing treatment duration alone or combined with enhanced case detection and/or cure under different HIV prevalence levels...
Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The GambiaBouke C de Jong
Medical Research Council Laboratories, Banjul, The Gambia
J Infect Dis 198:1037-43. 2008..There is considerable variability in the outcome of Mycobacterium tuberculosis infection. We hypothesized that Mycobacterium africanum was less likely than M. tuberculosis to transmit and progress to tuberculosis disease...
Transmission of isoniazid-resistant tuberculosisMartien W Borgdorff
J Infect Dis 190:650; author reply 650-1. 2004
High incidence of pulmonary tuberculosis persists a decade after immigration, The NetherlandsAnnelies M Vos
Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
Emerg Infect Dis 10:736-9. 2004..Possible explanations are reactivation of old infections and infection transmitted after immigration. Control policies should be determined on the basis of the as-yet unknown main causes of the persistent high incidence...
Trends in tuberculosis and the influence of HIV infection in northern Malawi, 1988-2001Martien W Borgdorff
AIDS 18:1465-7. 2004
HIV and tuberculosis in Ho Chi Minh City, Vietnam, 1997-2002Ngoc Buu Tran
Pham Ngoc Thach TB and Lung Disease Hospital, Ho Chi Minh City, Vietnam
Emerg Infect Dis 13:1463-9. 2007..9% increase to a 0.4% decrease per year. An emerging HIV epidemic, concentrated in young, male, injection drug users, is responsible for increased TB reporting rates in urban Vietnam...
Tuberculosis trends, VietnamMarleen Vree
Emerg Infect Dis 13:796-7. 2007
Steep increase in HIV prevalence among tuberculosis patients in Ho Chi Minh CityHoang T Quy
Pham Ngoc Thach Tuberculosis and Lung Diseases Centre, Ho Chi Minh City, Vietnam
AIDS 16:931-2. 2002..HIV prevalence increased steeply from 0.5% in 1995 to 4% in 2000, with a doubling time of approximately 21 months. This study highlights the need to intensify HIV/AIDS prevention and control in Vietnam...
Determining the burden of tuberculosis in Eritrea: a new approachMineab Sebhatu
National HIV AIDS and Tuberculosis Control Division, Ministry of Health, Asmara, Eritrea
Bull World Health Organ 85:593-9. 2007..To obtain an estimate of the prevalence of new cases of smear-positive tuberculosis in Eritrea using a new low-cost approach...
Antituberculosis drug resistance in the south of Vietnam: prevalence and trendsNguyen T Huong
National Hospital of Tuberculosis and Respiratory Diseases, Hanoi, Vietnam
J Infect Dis 194:1226-32. 2006..Therefore, a DOTS program can contain drug-resistant TB in this setting...
Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, VietnamNguyen Thi Ngoc Lan
Pham Ngoc Thach Tuberculosis and Lung Diseases Centre, Ho Chi Minh City, Vietnam
Emerg Infect Dis 9:1633-5. 2003..8, 95% confidence interval 1.5 to 5.2)...
Viewpoint: do we have enough data to estimate the current burden of tuberculosis? The example of BangladeshVikarunnessa Begum
National TB Control Programme, Directorate General of Health Services, Dhaka, Bangladesh
Trop Med Int Health 12:317-22. 2007..We reviewed nationwide epidemiological data on TB burden in Bangladesh to decide whether additional information is needed, in order to assess the current burden of TB...
Annual Mycobacterium tuberculosis infection risk and interpretation of clustering statisticsEmilia Vynnycky
London School of Hygiene and Tropical Medicine, London, England
Emerg Infect Dis 9:176-83. 2003..We conclude that, in some settings, clustering is an unreliable indicator of the extent of recent transmission...
Withholding TB treatment while awaiting susceptibility resultsMartien W Borgdorff
Int J Tuberc Lung Dis 7:705; author reply 705-6. 2003
Transposition rates of Mycobacterium tuberculosis IS6110 restriction fragment length polymorphism patternsPaul H C Eilers
Leiden University Medical Centre, Department of Medical Statistics, P O Box 9604, 2300 RC Leiden, The Netherlands
J Clin Microbiol 42:2461-4. 2004..The parameter most accurately describing changing RFLP patterns is the proportion of isolates with band changes, rather than the half-life or the rate of change...
Using capture-recapture methods to study recent transmission of tuberculosisMartien W Borgdorff
Int J Epidemiol 33:905-6; author reply 907. 2004
WHO, the Global Fund, and medical malpractice in malaria treatmentPeter J de Vries
Lancet 363:1161. 2004
Boosting of Quantiferon by TSTMartien W Borgdorff
Int J Tuberc Lung Dis 11:1381; author reply 1381. 2007
