Research Topics
| C J BuskensSummaryAffiliation: Gelre Hospitals Country: The Netherlands Publications
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Detail Information
Publications
Analysis of micrometastatic disease in histologically negative lymph nodes of patients with adenocarcinoma of the distal esophagus or gastric cardiaC J Buskens
Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Dis Esophagus 21:488-95. 2008..Therefore, this technique has the potential to refine the staging system for esophageal cancer and to help identify patients who will not be cured by surgery alone...
Encephalopathy and MRI abnormalities in fat embolism syndrome: a case reportChristianne J Buskens
Department of Surgery, Gelre Ziekenhuizen, Apeldoorn, The Netherlands
Med Sci Monit 14:CS125-9. 2008..Fat embolism syndrome can be a life-threatening condition, but the latent form that occurs 24 to 72 hours after the trauma is frequently described as a self-limiting condition...
Histopathologic evaluation of an animal model for Barrett's esophagus and adenocarcinoma of the distal esophagusChristianne J Buskens
Department of Surgery, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
J Surg Res 135:337-44. 2006....
Positive peritruncal nodes for esophageal carcinoma. not always a dismal prognosisJ B Hulscher
Department of Surgery, Academic Medical Center University of Amsterdam, The Netherlands
Dig Surg 18:98-101. 2001..With the development of new diagnostic tools more/smaller peritruncal nodes may be found positive preoperatively. We evaluate whether it is justified to exclude all patients with positive peri-truncal nodes from curative surgery...
Decreased incidence of isolated tumor cells in lymph nodes after laparoscopic resection for colorectal cancerE S van der Zaag
Department of Surgery, Gelre Ziekenhuizen Apeldoorn, Albert Schweitzerlaan 31, 7334 DZ Apeldoorn, The Netherlands
Surg Endosc 25:3652-7. 2011..We assessed the effect of the surgical approach (open versus no-touch laparoscopic) on the presence of tumor cells in sentinel lymph nodes (SN) of patients with stage I and II colorectal cancer...
Diagnosing occult tumour cells and their predictive value in sentinel nodes of histologically negative patients with colorectal cancerE S van der Zaag
Department of Surgery, Gelre Ziekenhuizen, Albert Schweitzerlaan 31, 7334 DZ Apeldoorn, The Netherlands
Eur J Surg Oncol 36:350-7. 2010..Also the reproducibility of diagnosing occult tumour cells (OTC) and the sensitivity of three different antibodies was assessed...
Comparison of cyclooxygenase 2 expression in adenocarcinomas of the gastric cardia and distal oesophagusC J Buskens
Department of Surgery, Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands
Gut 52:1678-83. 2003..However, it is still a matter of debate whether these malignancies have the same pathogenesis and genotype...
Adenocarcinoma of the esophagus with choroidal metastasisC J Buskens
Department of Surgery, Academic Medical Center University of Amsterdam, The Netherlands
Dis Esophagus 14:70-2. 2001..The patient received palliative external beam irradiation to the right eye for visual restoration, but she died before any beneficial effect was achieved...
Disturbed anastomotic healing after esophagectomy: a novel treatment of a benign tracheo-neo-esophageal fistulaC J Buskens
Department of Surgery, University of Amsterdam, Antoni van Leeuwenhoek Hospital Amsterdam, The Netherlands
Dig Surg 19:88-91. 2002..Over a period of 8 weeks, the long mediastinal fistula track obliterated, and after removal of the T-drain the (neo-)esophagocutaneous fistula closed rapidly...
Improving staging accuracy in colon and rectal cancer by sentinel lymph node mapping: a comparative studyE S van der Zaag
Department of Surgery, Gelre Ziekenhuizen, Albert Schweitzerlaan 31, 7334 DZ Apeldoorn, The Netherlands
Eur J Surg Oncol 35:1065-70. 2009..To compare the predictive value of sentinel lymph node (SN) mapping between patients with colon and rectal cancer...
Benign tracheo-neo-esophageal fistulas after subtotal esophagectomyC J Buskens
Department of Surgery, Academic Medical Center University of Amsterdam, The Netherlands
Ann Thorac Surg 72:221-4. 2001..Benign tracheo-neo-esophageal fistulas after esophagectomy are rare and treatment can be challenging. They can result from perioperative tracheal injury or various postoperative complications...
Outcome of surgical treatment for early adenocarcinoma of the esophagus or gastro-esophageal junctionMarinke Westerterp
Department of Surgery, Academic Medical Center at the University of Amsterdam, Amsterdam, The Netherlands
Virchows Arch 446:497-504. 2005..After transhiatal surgical resection, almost half of the patients with T1sm2-sm3 lesions develop recurrent disease within 5 years, and therefore need additional therapy to improve survival...
Prognostic significance of elevated cyclooxygenase 2 expression in patients with adenocarcinoma of the esophagusChristianne J Buskens
Department of Surgery, Academic Medical Center, University of Amsterdam, The Netherlands
Gastroenterology 122:1800-7. 2002..These findings support the effort to initiate clinical studies to investigate the effect of COX-2 inhibitors as a novel (adjuvant) chemotherapeutic modality for the treatment of adenocarcinoma arising from Barrett's esophagus...
Neoadjuvant selective COX-2 inhibition down-regulates important oncogenic pathways in patients with esophageal adenocarcinomaJurriaan B Tuynman
Departments of Surgery, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Ann Surg 242:840-9, discussion 849-50. 2005..To evaluate the effects of neoadjuvant therapy with the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib in vitro and in patients with esophageal adenocarcinoma on COX-2 and MET expression...
The current state of cancer gene therapy and its application in esophageal carcinomaChristianne J Buskens
Department of Surgery, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands
Dig Surg 22:222-33. 2005....
Gene therapy for barrett's esophagus: adenoviral gene transfer in different intestinal modelsWillem A Marsman
AMC Liver Center, Academic Medical Center, Amsterdam, The Netherlands
Cancer Gene Ther 12:778-86. 2005..We conclude that although the adenovirus shows promising results in vitro, the current adenoviral vectors are probably not suitable for patients with Barrett's esophagus...
Prognostic role of cyclooxygenase-2 in neoadjuvant-treated patients with squamous cell carcinoma of the esophagusAnna Sivula
Department of Pathology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
Int J Cancer 116:903-8. 2005..In conclusion, COX-2 is not a prognostic marker in squamous cell carcinoma of the esophagus, but low COX-2 expression is associated with poor prognosis in the neoadjuvant-treated patients...
Prediction of appropriateness of local endoscopic treatment for high-grade dysplasia and early adenocarcinoma by EUS and histopathologic featuresChristianne J Buskens
Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
Gastrointest Endosc 60:703-10. 2004..These data can be used to identify patients for whom local endoscopic treatment may be appropriate...
Gene therapy for esophageal carcinoma: the use of an explant model to test adenoviral vectors ex vivoWillem A Marsman
Department of Experimental Hepatology, Academic Medical Center, Amsterdam, The Netherlands
Cancer Gene Ther 11:289-96. 2004..The transduction was limited and localized in specific cells. RGD-targeted adenovirus did not show an improved transduction in this system...
A genetically retargeted adenoviral vector enhances viral transduction in esophageal carcinoma cell lines and primary cultured esophageal resection specimensChristianne J Buskens
Academic Medical Center, Deptartment of Surgery, Suite G4 130, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Ann Surg 238:815-24; discussion 825-6. 2003..To evaluate if an integrin-retargeted adenoviral vector could establish a more efficient and tumor-specific gene transfer in esophageal carcinoma cells...
Cyclooxygenase-2 and gastric carcinogenesisKirsi Saukkonen
Department of Pathology, Helsinki University, Central Hospital, Helsinki, Finland
APMIS 111:915-25. 2003..Taken together these data support efforts to initiate clinical studies to investigate the effect of Cox-2 inhibitors as chemotherapeutic agents and as adjuvant treatment modalities against gastric neoplasias...
