Research Topics
| Yvette SeppenwooldeSummaryAffiliation: Erasmus MC Country: The Netherlands Publications
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Detail Information
Publications
Treatment precision of image-guided liver SBRT using implanted fiducial markers depends on marker-tumour distanceY Seppenwoolde
Department of Radiation Oncology, Daniel den Hoed Cancer Center, Erasmus Medical Center, Groene Hilledijk 301, 3075 EA Rotterdam, The Netherlands
Phys Med Biol 56:5445-68. 2011..In conclusion, the tumour position can be predicted accurately using implanted markers, but marker-guided set-up accuracy decreases with increasing distance between implanted markers and the tumour...
HDR prostate monotherapy: dosimetric effects of implant deformation due to posture change between TRUS- and CT-imagingYvette Seppenwoolde
Department of Radiation Oncology, ErasmusMC, Rotterdam, The Netherlands
Radiother Oncol 86:114-9. 2008..Inclusion of more patients in this study was planned, but because of the observed strong negative effects it is already concluded that the TRUS plan cannot be used for the last three fractions with a deviating patient set-up...
Accuracy of tumor motion compensation algorithm from a robotic respiratory tracking system: a simulation studyYvette Seppenwoolde
Department of Radiation Oncology, Division of Medical Physics, ErasmusMC, Rotterdam, The Netherlands
Med Phys 34:2774-84. 2007..In general, the simulations suggest that the applied combined use of internal and external markers allow the robot to accurately follow tumor motion even in the case of irregularities in breathing patterns...
Potentials and limitations of guiding liver stereotactic body radiation therapy set-up on liver-implanted fiducial markersWouter Wunderink
Erasmus Medical Center Daniel den Hoed Cancer Center, Department of Radiation Oncology, Groene Hilledijk 301, 3008AE Rotterdam, The Netherlands
Int J Radiat Oncol Biol Phys 77:1573-83. 2010..We investigated the potentials and limitations of guiding liver stereotactic body radiation therapy (SBRT) set-up on liver-implanted fiducial markers...
Comparison of macroscopic pathology measurements with magnetic resonance imaging and assessment of microscopic pathology extension for colorectal liver metastasesAlejandra Méndez Romero
Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
Int J Radiat Oncol Biol Phys 82:159-66. 2012..To compare pathology macroscopic tumor dimensions with magnetic resonance imaging (MRI) measurements and to establish the microscopic tumor extension of colorectal liver metastases...
Stereotactic body radiation therapy for liver tumors: impact of daily setup corrections and day-to-day anatomic variations on dose in target and organs at riskAlejandra Méndez Romero
Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands
Int J Radiat Oncol Biol Phys 75:1201-8. 2009..To assess day-to-day differences between planned and delivered target volume (TV) and organ-at-risk (OAR) dose distributions in liver stereotactic body radiation therapy (SBRT), and to investigate the dosimetric impact of setup corrections...
Pulmonary function following high-dose radiotherapy of non-small-cell lung cancerKatrien De Jaeger
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 55:1331-40. 2003..Tumor regression is associated with an improvement of FEV(1) and a decline of T(L,COc). Reperfusion was not associated with an improvement of global pulmonary function...
Regional differences in lung radiosensitivity after radiotherapy for non-small-cell lung cancerYvette Seppenwoolde
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 60:748-58. 2004..Irradiation of caudally located lung tumors resulted in a greater risk of RP than irradiation of tumors located in other parts of the lungs...
Significance of plasma transforming growth factor-beta levels in radiotherapy for non-small-cell lung cancerKatrien De Jaeger
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 58:1378-87. 2004..The aim of this study was to evaluate prospectively the time course of TGF-beta1 levels in patients irradiated for NSCLC in relation to the development of RP and dose-volume parameters...
Intrafractional tumor motion: lung and liverHiroki Shirato
Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
Semin Radiat Oncol 14:10-8. 2004..This article reviews the current basic knowledge on respiratory physiology and summarizes the accumulating knowledge on internal motion of lung and liver tumors...
Incorporating an improved dose-calculation algorithm in conformal radiotherapy of lung cancer: re-evaluation of dose in normal lung tissueKatrien De Jaeger
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Radiother Oncol 69:1-10. 2003..Dosimetric parameters for lung injury (e.g. MLD, V20) computed using both algorithms are strongly correlated making an easy conversion feasible. Dose-effect relations should be refitted when more accurate dose data is available...
Tumor location, cirrhosis, and surgical history contribute to tumor movement in the liver, as measured during stereotactic irradiation using a real-time tumor-tracking radiotherapy systemKei Kitamura
Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
Int J Radiat Oncol Biol Phys 56:221-8. 2003..To investigate the three-dimensional (3D) intrafractional motion of liver tumors during real-time tumor-tracking radiotherapy (RTRT)...
Comparing different NTCP models that predict the incidence of radiation pneumonitis. Normal tissue complication probabilityYvette Seppenwoolde
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 55:724-35. 2003..Thus, for the studied patient population, the MLD was the most accurate predictor for the incidence of radiation pneumonitis...
Portal imaging to assess set-up errors, tumor motion and tumor shrinkage during conformal radiotherapy of non-small cell lung cancerSara C Erridge
Edinburgh Cancer Centre, Western General Hospital, Crewe Road South, Edinburgh, UK
Radiother Oncol 66:75-85. 2003..Tumor shrinkage was observed. The position of the tumor on the planning CT scan did not always coincide with the average position as measured during treatment...
Three-dimensional intrafractional movement of prostate measured during real-time tumor-tracking radiotherapy in supine and prone treatment positionsKei Kitamura
Department of Radiology, Hokkaido University School of Medicine, Sapporo, Japan
Int J Radiat Oncol Biol Phys 53:1117-23. 2002..To quantify three-dimensional (3D) movement of the prostate gland with the patient in the supine and prone positions and to analyze the movement frequency for each treatment position...
Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapyYvette Seppenwoolde
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
Int J Radiat Oncol Biol Phys 53:822-34. 2002..Tumor motion and hysteresis could be modeled with an asymmetric function with varying asymmetry. Tumor motion due to breathing was greatest in the cranial-caudal direction for lower-lobe unfixed tumors...
Optimizing radiation treatment plans for lung cancer using lung perfusion informationYvette Seppenwoolde
Department of Radiotherapy, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Radiother Oncol 63:165-77. 2002..CONCLUSION: Perfusion-weighted optimization resulted in clinically well applicable treatment plans, which cause less radiation damage to functioning lung for patients with large perfusion defects...
