Research Topics
| W WielingSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Autonomic neuropathy in Fabry disease: a prospective study using the Autonomic Symptom Profile and cardiovascular autonomic function testsMarieke Biegstraaten
Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
BMC Neurol 10:38. 2010..The aim of our study was to investigate autonomic symptoms and cardiovascular autonomic function in a large cohort of male and female Fabry patients...- [Initial diagnostic strategy in the case of transient losses of consciousness: the importance of the medical history]W Wieling
Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
Ned Tijdschr Geneeskd 147:849-54. 2003.... - Symptoms and signs of syncope: a review of the link between physiology and clinical cluesWouter Wieling
Department of Internal Medicine, Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands
Brain 132:2630-42. 2009..Complete loss of consciousness occurs with the 'turning up' of the eyeballs. Profound cerebral hypoperfusion may be accompanied by myoclonic jerks... - Orthostatic tolerance: salt, water and the autonomic nervous systemW Wieling
Academic Medical Centre, University of Amsterdam, Department of Internal Medicine, Room F4, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Clin Auton Res 12:234-5. 2002 - Hemodynamic mechanisms underlying prolonged post-faint hypotensionWouter Wieling
Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Clin Auton Res 21:405-13. 2011..However, in some patients prolonged post faint hypotension (PPFH) is observed. We assessed the hemodynamics underlying PPFH in a retrospective study... - Reflex syncope in children and adolescentsWouter Wieling
Academic Medical Center, University of Amsterdam, PO Box 22700, 1100DE Amsterdam, The Netherlands
Heart 90:1094-100. 2004 - Initial orthostatic hypotension as a cause of recurrent syncope: a case reportW Wieling
Department of Internal Medicine, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
Clin Auton Res 11:269-70. 2001..In patients using medications such as antidepressants, initial transient hypotension should be considered as the cause of falls and syncope... - Initial orthostatic hypotension: review of a forgotten conditionWouter Wieling
Department of Internal Medicine, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
Clin Sci (Lond) 112:157-65. 2007..This review alerts clinicians and clinician scientists to a common, yet often neglected, condition that occurs only upon an active change of posture and discusses its epidemiology, pathophysiology and management... - Extracellular fluid volume expansion in patients with posturally related syncopeW Wieling
Academic Medical Centre, University of Amsterdam, Department of Internal Medicine, Room F4, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Clin Auton Res 12:242-9. 2002 - Nonpharmacological treatment of reflex syncopeWouter Wieling
Dept of Internal Medicine, Academic Medical Center University of Amsterdam Room F4 221, P O Box 22700, 1100 DE Amsterdam, The Netherlands
Clin Auton Res 14:62-70. 2004..Preliminary data suggest that water drinking may improve orthostatic tolerance. Abdominal belts may also be effective in highly symptomatic subjects with reflex syncope... - Neural circulatory control in vasovagal syncopeJ J van Lieshout
Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
Pacing Clin Electrophysiol 20:753-63. 1997..The nature of the vasodilatation associated with the vasovagal response has still not been settled... - Management of vasovagal syncope: controlling or aborting faints by leg crossing and muscle tensingC T Paul Krediet
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
Circulation 106:1684-9. 2002..CONCLUSIONS: Leg crossing combined with tensing muscles at the onset of prodromal symptoms can postpone and in some subjects prevent vasovagal syncope... - Leg crossing, muscle tensing, squatting, and the crash position are effective against vasovagal reactions solely through increases in cardiac outputC T Paul Krediet
Academic Medical Center Univ of Amsterdam, Dept of Internal Medicine, Amsterdam, The Netherlands
J Appl Physiol 99:1697-703. 2005..No maneuver caused significant change in total peripheral resistance. We conclude that the mechanism underlying the effects of these maneuvers is exclusively an increase in CO... - Central and cerebrovascular effects of leg crossing in humans with sympathetic failureMark P M Harms
Department of Internal Medicine, AMC Center for Heart Failure Research, Academic Medical Center, Amsterdam, The Netherlands
Clin Sci (Lond) 118:573-81. 2010.... - Mechanisms underlying the impairment in orthostatic tolerance after nocturnal recumbency in patients with autonomic failureS Omboni
Department of Internal Medicine, Meibergdreef 9, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands
Clin Sci (Lond) 101:609-18. 2001..Not only nocturnal polyuria, but also a redistribution of body fluid, are likely mechanisms underlying the pronounced decreases in stroke volume and cardiac output after prolonged recumbency at night... - Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failureJ J van Lieshout
Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
Clin Auton Res 10:35-42. 2000..Preliminary data suggest that the expanded body fluid volume is allocated to the perivascular space rather than to the intravascular space... - Prospective evaluation of non-pharmacological treatment in vasovagal syncopeJacobus J C M Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, J1b 214, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
Europace 12:567-73. 2010..We examined the effects of this non-pharmacological treatment in patients with frequent recurrences... - Use of lower abdominal compression to combat orthostatic hypotension in patients with autonomic dysfunctionAdrianus A J Smit
Dept. of Internal Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Clin Auton Res 14:167-75. 2004..05). We conclude that in patients with neurogenic orthostatic hypotension, abdominal compression increases standing blood pressure to a varying degree by increasing stroke volume... - Diagnostic value of history taking in reflex syncopeN Colman
Dept. of Internal Medicine, Room F4-221, Academic Medical Centre, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands
Clin Auton Res 14:37-44. 2004..However, a prospective study of the value of the medical history for the diagnosis of syncope with long-term follow-up has not been performed... - Sleep syncope: important clinical associations with phobia and vagotoniaL Busweiler
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Sleep Med 11:929-33. 2010..To compare demographic and clinical data from patients with sleep syncope to those of patients with "classical" vasovagal syncope [VVS] collected over the last 8 years... - Prolonged post-faint hypotension can be reversed by dynamic tensionW Wieling
Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Clin Auton Res 21:415-8. 2011..During PPFH, when vagal activity is extreme, patients may require central stimulation as well as correction of venous return... - A patient with recurrent syncope and ST-elevation on the electrocardiogramN Colman
Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands
Europace 6:296-300. 2004..After treatment with nifedipine she has had one syncopal spell in a follow up period of 31 months. We conclude that the syncopal events in this patient were caused by a combination of vasovagal syncope and coronary spasm... - [A patient with an unexplained loss of consciousness: a case for the neurologist or the cardiologist?]N Colman
Academisch Medisch Centrum/Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
Ned Tijdschr Geneeskd 147:841-3. 2003..Knowledge of these triggers and the epidemiology of loss of consciousness might prevent the patients from being examined by different specialists and undergoing unnecessary additional tests... - Psychological treatment of malignant vasovagal syncope due to bloodphobiaN van Dijk
Academic Medical Centre, Department of Internal Medicine, F4-221, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Pacing Clin Electrophysiol 24:122-4. 2001..He was treated using systematic desensitization with muscular tension and cognitive techniques by the Pediatric Psychosocial Department and has not experienced syncopal events again... - Effectiveness of physical counterpressure maneuvers in preventing vasovagal syncope: the Physical Counterpressure Manoeuvres Trial (PC-Trial)Nynke van Dijk
Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
J Am Coll Cardiol 48:1652-7. 2006..In this study, we assessed the effectiveness of physical counterpressure maneuvers (PCM) in daily life... - High diagnostic yield and accuracy of history, physical examination, and ECG in patients with transient loss of consciousness in FAST: the Fainting Assessment studyNynke van Dijk
Departments of Internal Medicine, Academic Medical Center, University of Amsterdam AMC UvA, Amsterdam, The Netherlands
J Cardiovasc Electrophysiol 19:48-55. 2008..Transient loss of consciousness (TLOC) is a common clinical problem... - Low creatine kinase is associated with a high population incidence of faintingLizzy M Brewster
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Clin Auton Res 19:231-6. 2009..The aim of this observational study was to explore the association of vasovagal syncope with low CK... - Clinical factors associated with quality of life in patients with transient loss of consciousnessNynke van Dijk
Department of Internal Medicine, Academic Medical Center University of Amsterdam, The Netherlands
J Cardiovasc Electrophysiol 17:998-1003. 2006.... - Daily, weekly, monthly, and seasonal patterns in the occurrence of vasovagal syncope in an older populationNynke van Dijk
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, 1100 DE, Amsterdam, The Netherlands
Europace 9:823-8. 2007..The aim of this study was to assess the frequency of vasovagal episodes over the day, week, month, and seasons... - Management of initial orthostatic hypotension: lower body muscle tensing attenuates the transient arterial blood pressure decrease upon standing from squattingC T Paul Krediet
Department of Internal Medicine, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
Clin Sci (Lond) 113:401-7. 2007..In conclusion, LBMT is a new intervention to attenuate the transient blood pressure decrease after standing up from squatting, and IOH patients should be advised about the use of this manoeuvre... - Diagnosing vasovagal syncope based on quantitative history-taking: validation of the Calgary Syncope Symptom ScoreJacobus J C M Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands
Eur Heart J 30:2888-96. 2009..The Calgary Syncope Symptom Score (Calgary Score) is a tool developed for this purpose. We studied its performance in a series of patients presenting with T-LOC... - [Preventing fainting due to needles or blood]Linde A D Busweiler
Academisch Medisch Centrum, Amsterdam, The Netherlands
Ned Tijdschr Geneeskd 154:A1847. 2010..It can be treated with simple interventions like drinking water and performing counterpressure manoeuvres. Psychological deconditioning is an effective additional therapy... - Value of history-taking in syncope patients: in whom to suspect long QT syndrome?Nancy Colman
Department of Cardiology B2, Academic Medical Centre, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
Europace 11:937-43. 2009..Long QT syndrome (LQTS), a potentially fatal disorder, has to be distinguished from non-fatal conditions. Our aim was to investigate whether history-taking can be used in identifying patients likely to have LQTS... - Optimizing squatting as a physical maneuver to prevent vasovagal syncopeC T Paul Krediet
Dept of Internal Medicine, Academic Medical Center at the University of Amsterdam, F4 222 Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Clin Auton Res 18:179-86. 2008..We tested the hypothesis that lower body skeletal muscle tensing (LBMT) attenuates the decrease of mean arterial blood pressure (MAP) upon standing from squatting when used as a maneuver to prevent vasovagal syncope... - Is fatigue in Marfan syndrome related to orthostatic intolerance?Nynke van Dijk
Dept of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Clin Auton Res 18:187-93. 2008..Patients with Marfan syndrome are fatigued and have low orthostatic tolerance, which are significantly correlated. Patients could be educated in physical counterpressure maneuvers to increase orthostatic tolerance... - Influence of age and gender on the occurrence and presentation of reflex syncopeJacobus J C M Romme
Department of Clinical Epidemiology Biostatistics and Bioinformatics J1b 207 1, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Clin Auton Res 18:127-33. 2008..Knowledge of the variation in incidence and clinical features of reflex syncope by age and gender provides important background information to acquire an accurate diagnosis... - Edward P. Sharpey-Schafer was right: evidence for systemic vasodilatation as a mechanism of hypotension in cough syncopeC T Paul Krediet
Department of Internal Medicine, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, F4 222, 1105 AZ, Amsterdam, The Netherlands
Europace 10:486-8. 2008..Sharpey-Schafer's hypothesis that a decrease of total peripheral resistance plays a pivotal role in the pathophysiology of cough syncope. Systematic studies are needed to confirm this mechanism in larger series of patients... - Quality of life within one year following presentation after transient loss of consciousnessNynke van Dijk
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Am J Cardiol 100:672-6. 2007..Physicians should particularly pay attention to patients who are older, have recurrent episodes, a neurologic or psychogenic diagnosis, and a higher level of co-morbidity because these patients are vulnerable to a relatively poorer QoL... - Reliability, validity and responsiveness of the syncope functional status questionnaireNynke van Dijk
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Gen Intern Med 22:1280-5. 2007..Patients with transient loss of consciousness (TLOC) have poor health-related quality of life (HR-QoL)... - Orthostatic blood pressure control in Marfan's syndromeNynke van Dijk
Department of Internal Medicine F4-222, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Europace 7:25-7. 2005..When orthostatic complaint are reported by patients with Marfan's syndrome, physical counterpressure manoeuvers should be advised to reduce symptoms of postural hypotension... - Perfusion of the human brain: a matter of interactionsJohannes J van Lieshout
Department of Internal Medicine, F7-205, Cardiovascular Research Institute, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
J Physiol 551:402. 2003 - Orthostatic intolerance after space flightWouter Wieling
Department of Internal Medicine, Room F4 221, Academic Medical Centre, Cardiovascular Research Institute, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The
J Physiol 538:1. 2002..Despite the difficulties of performing such measurements on the space shuttle and the small numbers of astronauts involved, unique data are set forth that represent a major advance in our understanding of the physiology of space flight... - Long-term effects of carotid sinus denervation on arterial blood pressure in humansArthur A J Smit
Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
Circulation 105:1329-35. 2002..Therefore, in contrast to earlier experimental observations, the compensatory ability of the baroreceptor areas outside the carotid sinus seems to be of limited importance in the regulation of BP in humans... - Arterial baroreflex and peripheral chemoreflex function after radiotherapy for laryngeal or pharyngeal cancerHenri J L M Timmers
Department of Internal Medicine, University Medical Center, Nijmegen, The Netherlands
Int J Radiat Oncol Biol Phys 53:1203-10. 2002..We investigated whether radiation therapy for laryngeal or pharyngeal cancer affects baroreflex and chemoreflex function... - Sublingual nitroglycerin used in routine tilt testing provokes a cardiac output-mediated vasovagal responseJanneke Gisolf
Department of Physiology, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
J Am Coll Cardiol 44:588-93. 2004.... - Hemodynamic effects of leg crossing and skeletal muscle tensing during free standing in patients with vasovagal syncopeNynke van Dijk
Academic Medical Center, Dept of Internal Medicine, PO Box 22660, 1100 DD Amsterdam, The Netherlands
J Appl Physiol 98:584-90. 2005..3%; P < 0.01). Muscle tensing produced an additional increase in CO (+8.3%; P < 0.01) and mean arterial pressure (+7.8%; P < 0.01). The rise in BP during leg crossing was larger in the elderly... - Syncope, cerebral perfusion, and oxygenationJohannes J van Lieshout
Cardiovascular Research Institute Amsterdam and Departments of Medicine and Physiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
J Appl Physiol 94:833-48. 2003..Redistribution of cardiac output may affect cerebral perfusion by increased cerebral vascular resistance, supporting the view that cerebral perfusion depends on arterial inflow pressure provided that there is a sufficient cardiac output... - Pilots with vasovagal syncope: fit to fly?N van Dijk
Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
Aviat Space Environ Med 74:571-4. 2003..g., medical) situations, with clear prodromal symptoms and/or effective therapy, should be declared fit to fly. A symptom-free period and/or restriction to fly 'as or with a co-pilot' can be considered... - Endocrine factors related to changes in total peripheral vascular resistance after treatment of thyrotoxic and hypothyroid patientsM J Diekman
Department of Endocrinology, Academic Medical Centre, University of Amsterdam, The Netherlands
Eur J Endocrinol 144:339-46. 2001..Changes in TPR are not related to plasma adrenomedullin concentrations, but 46% could be explained by changes in T3. Altered ANP secretion and adrenergic tone may contribute to the T3-induced changes in TPR... - Exercise related syncope, when it's not the heartC T Paul Krediet
Dept. of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Clin Auton Res 14:25-36. 2004..The focus is on underlying mechanisms, clinical considerations, and outlining treatment strategies for these syndromes... - Vasovagal syncope interrupting sleep?C T P Krediet
Department of Internal Medicine, Academic Medical Centre/University of Amsterdam, Amsterdam, The Netherlands
Heart 90:e25. 2004..More polysomnographic monitoring data are required to confirm the diagnosis of vasovagal syncope interrupting sleep. This will be difficult because, although the condition may not be rare, the episodes are usually sporadic... - The fainting larkW Wieling
Academic Medical Centre, Amsterdam, The Netherlands
Clin Auton Res 12:207. 2002 - Baroreflex failure: a neglected type of secondary hypertensionH J L M Timmers
Department of Internal Medicine, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Neth J Med 62:151-5. 2004..Patients with suspected baroreflex failure should be referred to specialised centres for diagnostic testing and treatment... - Manoeuvres to combat vasovagal syncopeC T Paul Krediet
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
Europace 5:303. 2003 - Lifetime cumulative incidence of syncope in the general population: a study of 549 Dutch subjects aged 35-60 yearsKarin S Ganzeboom
Department of Internal Medicine, Academic Medcial Hospital, Amsterdam, The Netherlands
J Cardiovasc Electrophysiol 17:1172-6. 2006..Females experience syncope more often than males. The majority of the syncope triggers were related to conditions that affect orthostatic blood pressure regulation and vasomotor responses... - Syncope prevalence in the ED compared to general practice and population: a strong selection processLouise R A Olde Nordkamp
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Am J Emerg Med 27:271-9. 2009..94% of the patients visiting the ED/CPU presented with TLOC (n = 672), of which half had syncope. Only a small but probably selected group of all people with syncope visit the ED/CPU... - Score indices for predicting electrophysiologic outcomes in patients with unexplained syncopeLin Y Chen
Division of Cardiovascular Diseases, Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA, and Department of Internal Medicine, University of Amsterdam, Academic Medical Centre, The Netherlands
J Interv Card Electrophysiol 14:99-105. 2005..60, respectively. CONCLUSIONS: We have constructed diagnostic score indices for EP outcomes of bradyarrhythmia and VT in syncope. Of all the score indices, the model for His-Purkinje system disease has the highest predictive power... - Syncope during exercise, documented with continuous blood pressure monitoring during ergometer testingC T Paul Krediet
Academic Medical Center University of Amsterdam, Dept of Internal Medicine, F4 222, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands
Clin Auton Res 15:59-62. 2005.... - Prevalence and triggers of syncope in medical studentsKarin S Ganzeboom
Department of Internal Medicine F4-221, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Am J Cardiol 91:1006-8, A8. 2003 - Nexfin noninvasive continuous blood pressure validated against Riva-Rocci/KorotkoffDaan W Eeftinck Schattenkerk
Special Medical Care, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Am J Hypertens 22:378-83. 2009..The latest development using this methodology is the Nexfin monitor. The present study evaluated the accuracy of Nexfin noninvasive arterial pressure (NAP) compared with auscultatory BP measurements (Riva-Rocci/Korotkoff, RRK)... - Genetic aspects of vasovagal syncope: a systematic review of current evidenceLouise R A Olde Nordkamp
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Europace 11:414-20. 2009..Knowledge on genetic aspects of VVS could be very useful in clinical practice and research, but the current evidence that it has a genetic basis is not very strong... - Mind-stretching faintsRoland D Thijs
Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands
Epileptic Disord 9:418-23. 2007 - Baroreflex control of muscle sympathetic nerve activity after carotid body tumor resectionHenri J L M Timmers
Department of General Internal Medicine, University Medical Center Nijmegen, Nijmegen, The Netherlands
Hypertension 42:143-9. 2003..During the Valsalva maneuver, loss of carotid baroreflex control of heart rate is less well compensated for by the extra carotid baroreceptors than the control of muscle sympathetic nerve activity... - Leg crossing with muscle tensing, a physical counter-manoeuvre to prevent syncope, enhances leg blood flowJan T Groothuis
Department of Physiology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Clin Sci (Lond) 112:193-201. 2007..In conclusion, the present study indicates that the physical counter-manoeuvre of leg crossing combined with muscle tensing clearly enhances leg blood flow and, at the same time, elevates MAP... - Prevalence and clinical outcomes of patients with multiple potential causes of syncopeLin Y Chen
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 78:414-20. 2003..CONCLUSION: Of the patients evaluated for syncope, 18.4% had multiple potential causes. The presence of multiple potential causes was an independent predictor of increased mortality among patients with syncope... - Baroreflex and chemoreflex function after bilateral carotid body tumor resectionHenri J L M Timmers
Department of General Internal Medicine 541, Department of Otorhinolaryngology, University Medical Center St Radboud, Geert Grooteplein Zuid 8, PO Box 9101, 6500 HB Nijmegen, The Netherlands
J Hypertens 21:591-9. 2003..To investigate whether bilateral carotid body tumor resection invariably and chronically affects arterial baroreflex or peripheral chemoreflex function... - The role of carotid chemoreceptors in the sympathetic activation by adenosine in humansHenri J L M Timmers
Department of General Internal Medicine, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
Clin Sci (Lond) 106:75-82. 2004..In addition, blunting of the baroreflex sympathetic response to adenosine-induced hypotension may indicate a direct sympatho-inhibitory effect of adenosine... - Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive SummaryMichele Brignole
Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
Eur Heart J 25:2054-72. 2004 - Unconscious confusion--a literature search for definitions of syncope and related disordersRoland D Thijs
Dept. of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, 9600, 2300 RC Leiden, The Netherlands
Clin Auton Res 15:35-9. 2005..The lack of consistent terminology is likely to harm medical education, research, and patient care. There is a strong need for a systematic terminology for syncope and related conditions... - Guidelines on management (diagnosis and treatment) of syncope--update 2004Michele Brignole
Europace 6:467-537. 2004 - Fainting in your sleep?David L Jardine
Dept. of General Medicine, Christchurch Hospital, Christchurch, New Zealand
Clin Auton Res 16:76-8. 2006 - Leg crossing improves orthostatic tolerance in healthy subjects: a placebo-controlled crossover studyC T Paul Krediet
Dept Internal Medicine, Academic Medical Center, Univ of Amsterdam, Rm F4 222, Meibergdreef 9 1105AZ, Postbox 22660 1100DD, Netherlands
Am J Physiol Heart Circ Physiol 291:H1768-72. 2006..05); and there was a trend toward lower thoracic impedance. Leg crossing increases orthostatic tolerance in healthy human subjects. As a measure of prevention, it is a worthwhile addition to the management of vasovagal syncope... - Lack of correlation between the responses to tilt testing and adenosine triphosphate test and the mechanism of spontaneous neurally mediated syncopeMichele Brignole
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
Eur Heart J 27:2232-9. 2006.... - Impact of age on the vasovagal response provoked by sublingual nitroglycerine in routine tilt testingBart Verheyden
Laboratory of Experimental Cardiology, University Hospital Gasthuisberg, K U Leuven, Leuven, Belgium
Clin Sci (Lond) 113:329-37. 2007..Age-related differences in the laboratory presentation of a vasovagal episode depend on the magnitude of the underlying bradycardic response... - Respiratory countermaneuvers in autonomic failureRoland D Thijs
Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands
Neurology 69:582-5. 2007..Selective increase of inspiratory impedance augments blood pressure in healthy subjects through activation of the respiratory pump. We studied the efficacy of respiratory maneuvers to reduce orthostatic hypotension in autonomic failure... - Long-term effects of unilateral carotid endarterectomy on arterial baroreflex functionHenri J L M Timmers
Dept of General Internal Medicine, University Medical Center Nijmegen, Geert Grooteplein Zuid 8, 6500 HB Nijmegen, The Netherlands
Clin Auton Res 14:72-9. 2004..We investigated the long-term effects of unilateral CE on baroreflex control of function and blood pressure... - The ACCF/AHA scientific statement on syncope needs rethinkingDavid G Benditt
J Am Coll Cardiol 48:2598-9; author reply 2599. 2006 - Syncope: a clinically guided diagnostic algorithmHoracio Kaufmann
Mount Sinai School of Medicine, Box 1052, New York, NY 10029, USA
Clin Auton Res 14:87-90. 2004..The tilt test and carotid sinus massage are useful to reproduce reflex syncope. An insertable subcutaneous loop recorder can provide prolonged ECG monitoring... - Defining and classifying syncopeRoland D Thijs
Dept. of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, P.O. Box 9600, 2300 RC Leiden, The Netherlands
Clin Auton Res 14:4-8. 2004..Differences between syncope and other causes of TLOC such as epilepsy, and disorders mimicking TLOC are described. A pathophysiological classification of syncope is proposed... - Prognosis of transient neurological attacksJ Gert van Dijk
JAMA 299:1771-2; author reply 1772-3. 2008 - Vasovagal syncope or ventricular fibrillation. Your diagnosis better be accurateArthur A M Wilde
Clin Auton Res 17:203-5. 2007 - Is a syncope a syncope?Michele Brignole
Ital Heart J 4:145-7. 2003 - Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncopeMichele Brignole
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
Eur Heart J 27:1085-92. 2006..This prospective multicentre observational study assessed the efficacy of specific therapy based on implantable loop recorder (ILR) diagnostic observations in patients with recurrent suspected neurally mediated syncope (NMS)... - SyncopeDavid G Benditt
Cardiovascular Division, University of Minnesota, Minneapolis, USA
Curr Probl Cardiol 29:152-229. 2004..In many medical centers the evaluation of patients with syncope is haphazard, and may be substantially enhanced by establishment of a multidisciplinary syncope evaluation unit or team... - [Guidelines on management (diagnosis and treatment) of syncope. Update 2004. Executive summary]Michele Brignole
Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
Rev Esp Cardiol 58:175-93. 2005 - Variable day/night bias in 24-h non-invasive finger pressure against intrabrachial artery pressure is removed by waveform filtering and level correctionBerend E Westerhof
TNO TPD Biomedical Instrumentation, Milano, Italy
J Hypertens 20:1981-6. 2002....