Willem Kulik

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi Bloodspot assay using HPLC-tandem mass spectrometry for detection of Barth syndrome
    Willem Kulik
    Department of Clinical Chemistry, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Amsterdam, The Netherlands
    Clin Chem 54:371-8. 2008
  2. ncbi Cardiolipin and monolysocardiolipin analysis in fibroblasts, lymphocytes, and tissues using high-performance liquid chromatography-mass spectrometry as a diagnostic test for Barth syndrome
    Riekelt H Houtkooper
    Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Anal Biochem 387:230-7. 2009
  3. ncbi The enigmatic role of tafazzin in cardiolipin metabolism
    Riekelt H Houtkooper
    University of Amsterdam, Academic Medical Center, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Biochim Biophys Acta 1788:2003-14. 2009
  4. ncbi Detection of nonsterol isoprenoids by HPLC-MS/MS
    Linda Henneman
    Academic Medical Center, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Departments of Paediatrics Emma Children s Hospital and Clinical Chemistry, Amsterdam, The Netherlands
    Anal Biochem 383:18-24. 2008
  5. ncbi The effect of blood transfusion on pulmonary permeability in cardiac surgery patients: a prospective multicenter cohort study
    Alexander P J Vlaar
    Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Transfusion 52:82-90. 2012
  6. ncbi Identification and characterization of human cardiolipin synthase
    Riekelt H Houtkooper
    Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, University of Amsterdam, Academic Medical Center, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    FEBS Lett 580:3059-64. 2006
  7. ncbi Molecular characterization of iodotyrosine dehalogenase deficiency in patients with hypothyroidism
    Gijs Afink
    Laboratory Pediatric Endocrinology, Room G2 133, Academic Medical Center, University of Amsterdam, P O Box 22660, 1100 DD Amsterdam, The Netherlands
    J Clin Endocrinol Metab 93:4894-901. 2008
  8. ncbi HPLC-electrospray tandem mass spectrometry for rapid determination of dihydropyrimidine dehydrogenase activity
    Andre B P van Kuilenburg
    Emma Children s Hospital and Department of Clinical Chemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Chem 53:528-30. 2007
  9. ncbi Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS
    Linda Henneman
    Academic Medical Center, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Departments of Clinical Chemistry and Pediatrics, Amsterdam, The Netherlands
    Biochim Biophys Acta 1811:227-33. 2011
  10. ncbi The cellular and molecular mechanisms for neutropenia in Barth syndrome
    Vahagn Makaryan
    Department of Medicine, University of Washington, Seattle, WA, USA
    Eur J Haematol 88:195-209. 2012

Collaborators

  • Frederic M Vaz
  • Hans R Waterham
  • Colin G Steward
  • Marcus J Schultz
  • Gijs Afink
  • Andre B P van Kuilenburg
  • Ronald J A Wanders
  • AB Johan Groeneveld
  • Carrie Ris-Stalpers
  • Riekelt H Houtkooper
  • Alexander P J Vlaar
  • Linda Henneman
  • Vahagn Makaryan
  • Jorrit J Hofstra
  • Nicole P Juffermans
  • Arno G van Cruchten
  • Bwee Tien Poll-The
  • Henk van Lenthe
  • Fredoen Valianpour
  • David C Dale
  • Margreeth B Vroom
  • Andrew A Aprikyan
  • Alexander D Cornet
  • A B Johan Groeneveld
  • Christopher Allen
  • Albertus Beishuizen
  • Yigal Dror
  • Leendert Porcelijn
  • Marcel Levi
  • Anton T J Tool
  • Rienk Nieuwland
  • Dirk de Korte
  • Charlotte Thiels
  • Femke Stet
  • Richard J Rodenburg
  • Janet E Stone
  • Marjolein Turkenburg
  • Sabrina Malvagia
  • Amelia Morrone
  • Jan Smeitink
  • Daniela Karall
  • Celia Perez-Cerda
  • Michael W Amolins
  • Andrew T Placzek
  • Simone W Denis
  • Richard A Gibbs
  • Hana Akbari
  • Margrit Frentzen
  • Nicolaas G G M Abeling
  • Jan G M Huijmans
  • Marinus Duran

Detail Information

Publications13

  1. ncbi Bloodspot assay using HPLC-tandem mass spectrometry for detection of Barth syndrome
    Willem Kulik
    Department of Clinical Chemistry, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Amsterdam, The Netherlands
    Clin Chem 54:371-8. 2008
    ..Because early diagnosis and appropriate treatment are of key importance for the survival of affected boys, we developed a biochemical BTHS screening method based on analysis of the monolysocardiolipin:cardiolipin ratio in bloodspots...
  2. ncbi Cardiolipin and monolysocardiolipin analysis in fibroblasts, lymphocytes, and tissues using high-performance liquid chromatography-mass spectrometry as a diagnostic test for Barth syndrome
    Riekelt H Houtkooper
    Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Anal Biochem 387:230-7. 2009
    ....
  3. ncbi The enigmatic role of tafazzin in cardiolipin metabolism
    Riekelt H Houtkooper
    University of Amsterdam, Academic Medical Center, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Biochim Biophys Acta 1788:2003-14. 2009
    ..Transient expression of selected human tafazzin variants in BTHS fibroblasts showed for the first time in a human cell system that tafazzin lacking exon5 indeed functions in cardiolipin remodeling...
  4. ncbi Detection of nonsterol isoprenoids by HPLC-MS/MS
    Linda Henneman
    Academic Medical Center, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Departments of Paediatrics Emma Children s Hospital and Clinical Chemistry, Amsterdam, The Netherlands
    Anal Biochem 383:18-24. 2008
    ..This method will be suitable for measuring profiles of isoprenoid intermediates in cells with compromised isoprenoid biosynthesis and for determining the specificity of potential inhibitors of the pathway...
  5. ncbi The effect of blood transfusion on pulmonary permeability in cardiac surgery patients: a prospective multicenter cohort study
    Alexander P J Vlaar
    Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Transfusion 52:82-90. 2012
    ..Mediators of increased pulmonary vascular leakage after transfusion are unknown. We hypothesized that factors may include antibodies or bioactive lipids, which have been implicated in transfusion-related acute lung injury...
  6. ncbi Identification and characterization of human cardiolipin synthase
    Riekelt H Houtkooper
    Department of Clinical Chemistry, Laboratory Genetic Metabolic Diseases, University of Amsterdam, Academic Medical Center, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    FEBS Lett 580:3059-64. 2006
    ..The possible implications for CL synthesis and remodeling are discussed...
  7. ncbi Molecular characterization of iodotyrosine dehalogenase deficiency in patients with hypothyroidism
    Gijs Afink
    Laboratory Pediatric Endocrinology, Room G2 133, Academic Medical Center, University of Amsterdam, P O Box 22660, 1100 DD Amsterdam, The Netherlands
    J Clin Endocrinol Metab 93:4894-901. 2008
    ..The recent cloning of the human iodotyrosine deiodinase (IYD) gene enables the investigation of iodotyrosine dehalogenase deficiency, a form a primary hypothyroidism resulting from iodine wasting, at the molecular level...
  8. ncbi HPLC-electrospray tandem mass spectrometry for rapid determination of dihydropyrimidine dehydrogenase activity
    Andre B P van Kuilenburg
    Emma Children s Hospital and Department of Clinical Chemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Chem 53:528-30. 2007
    ..We developed a rapid and specific method to measure the DPD activity in peripheral blood mononuclear cells using HPLC tandem-mass spectrometry (HPLC-MS/MS)...
  9. ncbi Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS
    Linda Henneman
    Academic Medical Center, University of Amsterdam, Laboratory Genetic Metabolic Diseases, Departments of Clinical Chemistry and Pediatrics, Amsterdam, The Netherlands
    Biochim Biophys Acta 1811:227-33. 2011
    ..Our method can be used to test new inhibitors and their effect on overall isoprenoid biosynthesis...
  10. ncbi The cellular and molecular mechanisms for neutropenia in Barth syndrome
    Vahagn Makaryan
    Department of Medicine, University of Washington, Seattle, WA, USA
    Eur J Haematol 88:195-209. 2012
    ....
  11. ncbi Supernatant of aged erythrocytes causes lung inflammation and coagulopathy in a "two-hit" in vivo syngeneic transfusion model
    Alexander P J Vlaar
    Department of Intensive Care Medicine, Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands
    Anesthesiology 113:92-103. 2010
    ..Using a syngeneic in vivo transfusion model, we investigated whether transfusion of stored rat erythrocytes causes lung injury in healthy and in lipopolysaccharide-primed rats in a "two-hit" model of lung injury...
  12. ncbi Quantification of free sialic acid in urine by HPLC-electrospray tandem mass spectrometry: a tool for the diagnosis of sialic acid storage disease
    Fredoen Valianpour
    Academic Medical Center, University of Amsterdam, Emma Children's Hospital and Department of Clinical Chemistry, Amsterdam, The Netherlands
    Clin Chem 50:403-9. 2004
    ..CONCLUSIONS: The HPLC-tandem MS method for free sialic acid in urine is more rapid, accurate, sensitive, selective, and robust than earlier methods and may serve as a candidate reference method for free sialic acid in diagnosis of SSD...