A Alkemade

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi Expression of thyroid hormone transporters in the human hypothalamus
    Anneke Alkemade
    Academic Medical Center, University of Amsterdam, Department of Endocrinology and Metabolism, G2 136, 1105AZ Amsterdam, The Netherlands
    J Clin Endocrinol Metab 96:E967-71. 2011
  2. ncbi Central and peripheral effects of thyroid hormone signalling in the control of energy metabolism
    A Alkemade
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Neuroendocrinol 22:56-63. 2010
  3. ncbi Thyroid hormone signaling in the hypothalamus
    Anneke Alkemade
    Netherlands Institute for Neuroscience, Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Curr Opin Endocrinol Diabetes Obes 15:453-8. 2008
  4. ncbi Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice
    A Boelen
    Department of Endocrinology and Metabolism, F5 171, Academic Medical Center, Meibergdreef 9, Amsterdam, The Netherlands
    J Endocrinol 182:315-23. 2004
  5. ncbi Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation
    A Boelen
    Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands
    Endocrinology 146:5128-34. 2005
  6. ncbi The hypothalamic-pituitary-thyroid axis in critical illness
    E Fliers
    Department of Endocrinology and Metabolism, University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands
    Best Pract Res Clin Endocrinol Metab 15:453-64. 2001
  7. ncbi Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary
    Anneke Alkemade
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, The Netherlands
    Eur J Endocrinol 154:491-500. 2006
  8. ncbi Hypothalamic thyroid hormone feedback in health and disease
    Eric Fliers
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Prog Brain Res 153:189-207. 2006
  9. ncbi Neuroanatomical pathways for thyroid hormone feedback in the human hypothalamus
    Anneke Alkemade
    Department of Endocrinology and Metabolism, Academic Medical Center of the University of Amsterdam, P.O. Box 22700, 1100 DE, Amsterdam, The Netherlands
    J Clin Endocrinol Metab 90:4322-34. 2005
  10. ncbi Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary
    Anneke Alkemade
    Department of Endocrinology, Academic Medical Center of the University of Amsterdam, The Netherlands
    J Clin Endocrinol Metab 90:904-12. 2005

Collaborators

Detail Information

Publications12

  1. ncbi Expression of thyroid hormone transporters in the human hypothalamus
    Anneke Alkemade
    Academic Medical Center, University of Amsterdam, Department of Endocrinology and Metabolism, G2 136, 1105AZ Amsterdam, The Netherlands
    J Clin Endocrinol Metab 96:E967-71. 2011
    ..Monocarboxylate transporter (MCT)-8, MCT10, and organic anion transporting polypeptide 1C1 (OATP1C1) are the best-characterized specific thyroid hormone transporters to date...
  2. ncbi Central and peripheral effects of thyroid hormone signalling in the control of energy metabolism
    A Alkemade
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Neuroendocrinol 22:56-63. 2010
    ....
  3. ncbi Thyroid hormone signaling in the hypothalamus
    Anneke Alkemade
    Netherlands Institute for Neuroscience, Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Curr Opin Endocrinol Diabetes Obes 15:453-8. 2008
    ..Proper thyroid hormone signaling is essential for brain development and adult brain function. Signaling can be disrupted at many levels due to altered thyroid hormone secretion, conversion or thyroid hormone receptor binding...
  4. ncbi Simultaneous changes in central and peripheral components of the hypothalamus-pituitary-thyroid axis in lipopolysaccharide-induced acute illness in mice
    A Boelen
    Department of Endocrinology and Metabolism, F5 171, Academic Medical Center, Meibergdreef 9, Amsterdam, The Netherlands
    J Endocrinol 182:315-23. 2004
    ..Serum T(3) and T(4) fell only after 24 h. Our results suggested almost simultaneous involvement of the whole HPT axis in the downregulation of thyroid hormone metabolism during acute illness...
  5. ncbi Induction of type 3 deiodinase activity in inflammatory cells of mice with chronic local inflammation
    A Boelen
    Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands
    Endocrinology 146:5128-34. 2005
    ..In conclusion, local inflammation strongly induces D3 activity in inflammatory cells, especially in invading polymorphonuclear granulocytes, suggesting enhanced local degradation of T(3)...
  6. ncbi The hypothalamic-pituitary-thyroid axis in critical illness
    E Fliers
    Department of Endocrinology and Metabolism, University of Amsterdam, Amsterdam, 1105 AZ, The Netherlands
    Best Pract Res Clin Endocrinol Metab 15:453-64. 2001
    ..Recent clinical studies in these patients involving the administration of hypothalamic peptides open up new ways of achieving this...
  7. ncbi Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary
    Anneke Alkemade
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, The Netherlands
    Eur J Endocrinol 154:491-500. 2006
    ....
  8. ncbi Hypothalamic thyroid hormone feedback in health and disease
    Eric Fliers
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Prog Brain Res 153:189-207. 2006
    ..This model for thyroid hormone action in the human hypothalamus awaits confirmation in future experimental studies...
  9. ncbi Neuroanatomical pathways for thyroid hormone feedback in the human hypothalamus
    Anneke Alkemade
    Department of Endocrinology and Metabolism, Academic Medical Center of the University of Amsterdam, P.O. Box 22700, 1100 DE, Amsterdam, The Netherlands
    J Clin Endocrinol Metab 90:4322-34. 2005
    ....
  10. ncbi Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary
    Anneke Alkemade
    Department of Endocrinology, Academic Medical Center of the University of Amsterdam, The Netherlands
    J Clin Endocrinol Metab 90:904-12. 2005
    ....
  11. ncbi Functional neuroanatomy of thyroid hormone feedback in the human hypothalamus and pituitary gland
    Eric Fliers
    Department of Endocrinology and Metabolism F5 168, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    Mol Cell Endocrinol 251:1-8. 2006
    ..Production and action of T3 appear to occur in separate cell types of the human hypothalamus and anterior pituitary...
  12. ncbi Hypermetabolism in mice caused by the central action of an unliganded thyroid hormone receptor alpha1
    Maria Sjogren
    Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
    EMBO J 26:4535-45. 2007
    ..Furthermore, the data demonstrate that a nuclear hormone receptor affecting sympathetic signaling can override its autonomous effects in peripheral tissues...