Research Topics
| Wichai CherdshewasartSummaryAffiliation: Chulalongkorn University Country: Thailand Publications
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Detail Information
Publications
Correlation of antioxidant activity and major isoflavonoid contents of the phytoestrogen-rich Pueraria mirifica and Pueraria lobata tubersW Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
Phytomedicine 15:38-43. 2008..The correlation analysis between antioxidant activity and major isoflavonoid contents of plant tubers indicated a significant correlation only with puerarin and a significant lack of correlation with daidzin, daidzein and genistein...- Metabolic activation promotes estrogenic activity of the phytoestrogen-rich plantWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
Maturitas 59:128-36. 2008..We evaluated the influence of in vitro metabolic activation by S9 mixture on the estrogenic activity of tuberous samples of different cultivars of the phytoestrogen-rich herb, Pueraria mirifica, harvested in different seasons... - Pretreatment with phytoestrogen-rich plant decreases breast tumor incidence and exhibits lower profile of mammary ERalpha and ERbetaWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
Maturitas 58:174-81. 2007..Phytoestrogens have been reported to exhibit antiproliferation to human breast cancer cells in vitro. We tested the phytoestrogen-rich, Pueraria mirifica against rat breast cancer induction in vivo... - Androgen disruption and toxicity tests of Butea superba Roxb., a traditional herb used for treatment of erectile dysfunction, in male ratsWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok, Thailand
Maturitas 60:131-7. 2008..To evaluate the effects of the tuberous powder of Butea superba Roxb. (Leguminosae) on blood testosterone and luteinizing hormone (LH), and toxicity in male rats... - Evaluation of the estrogenic activity of the wild Pueraria mirifica by vaginal cornification assayWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
J Reprod Dev 53:385-93. 2007..The results demonstrate that the plant population shows differential estrogenic activity as evaluated by vaginal cornification assay... - Major isoflavonoid contents of the 1-year-cultivated phytoestrogen-rich herb, Pueraria mirificaWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Thailand
Biosci Biotechnol Biochem 71:2527-33. 2007..In conclusion, the tuberous storage of major isoflavonoids in 1-year-cultivated plants was greatly diverse and was strongly influenced by the season and plant genetics... - Antimutagenic potential of the Thai herb, Mucuna collettii LaceWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
J Ethnopharmacol 115:96-103. 2008..The overall mutagenic and antimutagenic assays are further evidences for the antimutagenic potential of Mucuna collettii... - Variance of estrogenic activity of the phytoestrogen-rich plantWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
Maturitas 61:350-7. 2008..To evaluate the influences of seasonal changes and plant cultivars on estrogenic activity of the phytoestrogen-rich plant, Pueraria mirifica... - Major isoflavonoid contents of the phytoestrogen rich-herb Pueraria mirifica in comparison with Pueraria lobataWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
J Pharm Biomed Anal 43:428-34. 2007..The difference in both cases should be mostly influenced by genetic and environmental factors. In comparison with P. lobata, P. mirifica population exhibited differences only with a lower amount of daidzein... - Determination of the estrogenic activity of wild phytoestrogen-rich Pueraria mirifica by MCF-7 proliferation assayWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
J Reprod Dev 54:63-7. 2008..Puerarin and 17 beta-estradiol at concentration of 10(-12)-10(-6) M exhibited no cytotoxicity in MCF-7... - The mutagenic and antimutagenic effects of the traditional phytoestrogen-rich herbs, Pueraria mirifica and Pueraria lobataW Cherdshewasart
Department of Biology, Chulalongkorn University, Bangkok, Thailand
Braz J Med Biol Res 42:816-23. 2009..The tests confirmed the non-mutagenic but reasonably antimutagenic activities of the two plant extracts, supporting their current use as safe dietary supplements and cosmetics... - Mutagenic and antimutagenic effects of the traditional herb used for treating erectile dysfunction, Butea superba RoxbWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
Biosci Biotechnol Biochem 74:923-7. 2010..superba products at low dose (not more than 781.25 microg/ml of the plant extract), but the in vivo genotoxic assay demonstrated the unsafe consumption at a high dose (300 mg/kg of the BW plant extract or 16 g/kg of the BW plant powder)... - The differential anti-proliferation effect of white (Pueraria mirifica), red (Butea superba), and black (Mucuna collettii) Kwao Krua plants on the growth of MCF-7 cellsW Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Bangkok 10330, Thailand
J Ethnopharmacol 93:255-60. 2004..Butea superba and Mucuna collettii exhibited only anti-proliferation effects on the growth of MCF-7 cells in relation with a possible anti-estrogen mechanism or a potent cytotoxic effect... - Clinical trial of Butea superba, an alternative herbal treatment for erectile dysfunctionW Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Bangkok 10330, Thailand
Asian J Androl 5:243-6. 2003..To study the effect of Butea superba on erectile dysfunction (ED) in Thai males... - Androgenic activity of the Thai traditional male potency herb, Butea superba Roxb., in female ratsSuchinda Malaivijitnond
Primate Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Bangkok 10330, Thailand
J Ethnopharmacol 121:123-9. 2009..Butea superba Roxb. (Leguminosae) is a well-known Thai male potency herb with androgenic and anti-estrogenic activities. We evaluated whether oral administration of Butea superba has an androgenic or anti-estrogenic activity in female rats... - Using vaginal cytology to assess the estrogenic activity of phytoestrogen-rich herbSuchinda Malaivijitnond
Primate Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Phyathai Road, Patumwan, Bangkok 10330, Thailand
J Ethnopharmacol 107:354-60. 2006.... - Assessment of fertility and reproductive toxicity in adult female mice after long-term exposure to Pueraria mirifica herbSukanya Jaroenporn
Interdepartment of Physiology, Faculty of Graduate School, Chulalongkorn University, Bangkok, Thailand
J Reprod Dev 53:995-1005. 2007.... - Preventive effects of Pueraria mirifica on bone loss in ovariectomized ratsNontakorn Urasopon
Biological Science Ph D Program, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
Maturitas 59:137-48. 2008..Effects of Pueraria mirifica on bone loss in fully mature ovariectomized rats are examined... - Effects of Pueraria mirifica, an herb containing phytoestrogens, on reproductive organs and fertility of adult male miceSukanya Jaroenporn
Interdepartment of Physiology, Faculty of Graduate School, Chulalongkorn University, Bangkok 10330, Thailand
Endocrine 30:93-101. 2006..Although PM-100 can cause some moderate impairment, no persistent effects were observed. Most of PM-treated mice increased the mating efficiency after stop treatment... - Assessment of urinary gonadotropin and steroid hormone profiles of female cynomolgus monkeys after treatment with Pueraria mirificaHataitip Trisomboon
Primate Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand
J Reprod Dev 53:395-403. 2007..This suggests that changes of urinary FSH levels can be considered an indicator for study of estrogenic effects on hormonal levels in female monkeys... - Effect of Pueraria mirifica on the sexual skin coloration of aged menopausal cynomolgus monkeysHataitip Trisomboon
Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
J Reprod Dev 52:537-42. 2006..The changes in sexual skin coloration were not dose-dependent. The present results indicate that PM had estrogenic action by increasing reddish sexual skin coloration in aged menopausal monkeys... - Estrogenic and anti-estrogenic activities of the Thai traditional herb, Butea superba RoxbWichai Cherdshewasart
Department of Biology, Faculty of Science, Chulalongkorn University, Patumwan, Bangkok, Thailand
Biosci Biotechnol Biochem 74:2176-82. 2010..The selected plant extracts tested exhibited antiestrogenic activity. Coincubation with the rat liver S9 mixture also elevated the estrogenic potency of these plant extracts... - Pueraria mirifica, a phytoestrogen-rich herb, prevents bone loss in orchidectomized ratsNontakorn Urasopon
Biological Science Ph D Program, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
Maturitas 56:322-31. 2007..We examined the effects of crude P. mirifica on bone loss and influences on reproductive organs in male rats... - Cytotoxic constituents from Butea superba RoxbNattaya Ngamrojanavanich
Research Centre for Bioorganic Chemistry, Faculty of Science, Chulalongkorn University, Pyathai Road, Pathumwan, Bangkok, Thailand
J Ethnopharmacol 109:354-8. 2007..Compounds 2 and 4 showed moderate cytotoxic activity on KB cell lines with IC(50) (microM) values of 37.3+/-2.5 and 71.1+/-0.8 and on BC cell lines with IC(50) (microM) values of 32.7+/-1.5 and 47.3+/-0.3, respectively... - Different effects of Pueraria mirifica, a herb containing phytoestrogens, on LH and FSH secretion in gonadectomized female and male ratsSuchinda Malaivijitnond
Primate Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand
J Pharmacol Sci 96:428-35. 2004..From this study, it can be concluded that P. mirifica can influence the reproductive functions in both sexes of rats, but the response in females is greater than in males... - The nucleotide sequences of the parathyroid gene in primates (suborder Anthropoidea)Suchinda Malaivijitnond
Primate Research Unit, Chulalongkorn University, Bangkok 10330, Thailand
Gen Comp Endocrinol 125:67-78. 2002..The apes are the most suitable animals to be used for studying the bone metabolism and applying the knowledge to clinical use in humans... - The estrogenic effect of Pueraria mirifica on gonadotrophin levels in aged monkeysHataitip Trisomboon
Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand
Endocrine 29:129-34. 2006..Moreover, they can be recovered, and there is a direct correlation between dosage and recovery time. PM may be effective as an alternative medicine in menopausal women because the effects are not permanent...