Research Topics
Genomes and Genes | Ming Fei LiuSummaryAffiliation: National Cheng Kung University Country: Taiwan Publications
| Collaborators
|
Detail Information
Publications
Distribution of double-negative (CD4- CD8-, DN) T subsets in blood and synovial fluid from patients with rheumatoid arthritisM F Liu
Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan, Republic of China
Clin Rheumatol 18:227-31. 1999..The lower percentage of circulating gammadelta DNT cells might have resulted from migration from the circulation into the synovium, suggesting a role for gammadelta DNT cells in the pathogenesis of rheumatoid synovitis...
Variable increased expression of program death-1 and program death-1 ligands on peripheral mononuclear cells is not impaired in patients with systemic lupus erythematosusMing Fei Liu
Section of Rheumatology and Immunology, Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan 704, Taiwan
J Biomed Biotechnol 2009:406136. 2009..The study indicates that there are no intrinsically defective expression and function of PD-1 and PD-1 ligands on PBMC in patients with SLE...
CTLA-4 gene polymorphism in promoter and exon-1 regions in Chinese patients with systemic lupus erythematosusM F Liu
Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan, Republic of China
Lupus 10:647-9. 2001..However, SLE is a very heterogeneous syndrome and CTLA-4 gene polymorphism might correlate with some specific clinical features. To exploring this possibility, subgroup analysis in more patients needs to be performed...
Decreased CD4+CD25+bright T cells in peripheral blood of patients with primary Sjogren's syndromeM F Liu
Section of Rheumatology and Immunology, Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan, Republic of China
Lupus 17:34-9. 2008..However, the exact functions of decreased circulating CD4+CD25+bright T cells in pSS need further elucidated...
Increased expression of soluble cytotoxic T-lymphocyte-associated antigen-4 molecule in patients with systemic lupus erythematosusM F Liu
Section of Rheumatology and Immunology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
Scand J Immunol 57:568-72. 2003..To the best of our knowledge, this is the first report showing that patients with SLE have increased sCTLA-4 expression. However, the mechanism and role of increased sCTLA-4 in the pathogenesis of SLE remains elucidated...
The presence of cytokine-suppressive CD4+CD25+ T cells in the peripheral blood and synovial fluid of patients with rheumatoid arthritisM F Liu
Section of Rheumatology and Immunology, Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan, Republic of China
Scand J Immunol 62:312-7. 2005....
Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosusM F Liu
Section of Rheumatology and Immunology, Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan, ROC
Scand J Immunol 59:198-202. 2004..To the best of our knowledge, this is the first study to demonstrate that patients with SLE had decreased CD4+CD25+ T cells. However, the exact role of the decreased CD4+CD25+ T cells in the pathogenesis of SLE remains to be elucidated...
Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammationChrong Reen Wang
Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Arthritis Rheum 52:1319-24. 2005..Kallistatin has been shown to be an angiogenesis inhibitor. In this study, we investigated whether adenovirus-mediated kallistatin gene delivery has a prophylactic effect in a rat arthritis model...
Common variable immunodeficiency mimicking rheumatoid arthritis with Sjögren's syndromeLi Hsin Lin
Section of Rheumatology and Section of Allergy and Immunology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
J Microbiol Immunol Infect 38:358-60. 2005..IVIG replacement therapy was ultimately successful in curing recurrent bacterial infections, chronic polyarthritis, and improving the severity of sicca syndrome...
Up-regulation of XCR1 expression in rheumatoid jointsC R Wang
Section of Rheumatology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Rheumatology (Oxford) 43:569-73. 2004..We studied 16 chemokine receptors of the CC, CXC, CX3C and C families by analysing venous blood and synovial fluid samples and synovial tissues from RA patients...
RANTES promoter polymorphism as a genetic risk factor for rheumatoid arthritis in the ChineseC R Wang
Section of Rheumatology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Clin Exp Rheumatol 23:379-84. 2005..There is increasing evidence suggesting a role of RANTES in the pathogenesis of rheumatoid arthritis (RA) and we evaluated the possible effect of RANTES gene on the susceptibility to RA in Chinese patients...
Regulation of CCR5 expression and MIP-1alpha production in CD4+ T cells from patients with rheumatoid arthritisC R Wang
Section of Rheumatology, Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan
Clin Exp Immunol 132:371-8. 2003..Production of MIP-1alpha by synovial fibroblasts is significantly increased by engagement of CD40 with CD40L. Synovial microenvironment plays a potential role in regulation of CCR5+CD4+ T cells in rheumatoid joints...
Expression of CD40 and CD40 ligand among cell populations within rheumatoid synovial compartmentM F Liu
Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan, ROC
Autoimmunity 34:107-13. 2001..We concluded that there was an intrinsic hyperexpression of CD40L on lymphoid cells within rheumatoid joints, and synovial fibroblasts could contribute to articular inflammation through surface CD40 molecule...
Incidence of cancer in a nationwide population cohort of 7852 patients with primary Sjogren's syndrome in TaiwanMeng Yu Weng
Department of Internal Medicine, Division of Allergy, Immunology, and Rheumatology, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan
Ann Rheum Dis 71:524-7. 2012..However, little is known with regard to the risk of developing cancers other than NHL. The authors aimed in this study to compare the incidence of cancer in various sites among patients with pSS with the general population of Taiwan...
The efficacy of low-dose mycophenolate mofetil for treatment of lupus nephritis in Taiwanese patients with systemic lupus erythematosusMeng Yu Weng
Section of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan, Republic of China
Clin Rheumatol 29:771-5. 2010..Our results suggest that lupus nephritis in Oriental patients might respond to lower doses of MMF than Caucasians...
Adult-onset acute rheumatic fever: possible resurgence in southern TaiwanChrong Reen Wang
Section of Rheumatology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
J Clin Rheumatol 11:146-9. 2005..By the late 1980s, acute rheumatic fever (ARF) had become a rare disease in Taiwan. The low prevalence rate in this area is attributed to a better economic status, which has led to improved public health and adequate medical services...
Deoxyribonuclease-inhibitory antibodies in systemic lupus erythematosusTrai Ming Yeh
Department of Medical Technology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
J Biomed Sci 10:544-51. 2003..Taken together, these results suggest that DNase-inhibitory antibodies which recognize a conserved epitope near the catalytic site of DNase may act in the pathogenesis of SLE...
Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritisYu Hsiang Hsu
National Cheng Kung University, Tainan, Taiwan
Arthritis Rheum 54:2722-33. 2006..Interleukin-20 (IL-20) has proinflammatory properties for keratinocytes. In this study, we sought to determine whether IL-20 is involved in RA...
Amelioration of collagen-induced arthritis in rats by adenovirus-mediated PTEN gene transferChrong Reen Wang
National Cheng Kung University Medical College, Tainan, Taiwan
Arthritis Rheum 58:1650-6. 2008..The aim of this study was to examine the effect of PTEN gene transfer in rats with collagen-induced arthritis (CIA)...
Aberrant integrin activation induces p38 MAPK phosphorylation resulting in suppressed Fas-mediated apoptosis in T cells: implications for rheumatoid arthritisYu Ping Lin
Institute of Basic Medical Sciences, National Cheng Kung University, Tainan, Taiwan, ROC
Mol Immunol 46:3328-35. 2009..In conclusion, abnormal activation of p38 MAPK to prevent Fas-mediated apoptosis may represent a common survival mechanism of RA synovial T cells contributing to the persistent inflammation of affected synovium...
Incidence and mortality of treated primary Sjogren's syndrome in Taiwan: a population-based studyMeng Yu Weng
Section of Allergy, Immunology, and Rheumatology, Department of Internal Medicine, National Cheng Kung University NCKU MedicalCollege and Hospital, Tainan, Taiwan
J Rheumatol 38:706-8. 2011..To estimate the incidence and mortality of treated primary Sjögren's syndrome (pSS) by sex and age group in Taiwan...
The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosusLi Hsin Lin
Section of Rheumatology and Immunology, Department of Internal Medicine, National Cheng Kung University Hospital, 138 Sheng Li Road, Tainan, Taiwan 704, Republic of China
J Rheumatol 38:1914-9. 2011..Our aims were to investigate the expression of IRF7 and its correlation with disease activity and to explore the association in Taiwanese patients between 2 genetic single-nucleotide polymorphisms (SNP) of IRF7 and SLE...
Hydroxychloroquine sulphate inhibits in vitro apoptosis of circulating lymphocytes in patients with systemic lupus erythematosusS T Liu
Department of Internal Medicine, En Chu Kong Hospital, Taipei and Tainan, ROC
Asian Pac J Allergy Immunol 19:29-35. 2001..We propose that this results in decreased stimulation of autoreactive lymphocytes reactive with self-peptides, and consequently diminution of activation-induced cell death (apoptosis) of mature peripheral lymphocytes...
A retrospective study of catastrophic invasive fungal infections in patients with systemic lupus erythematosus from southern TaiwanC T Weng
Section of Rheumatology and Immunology, National Cheng Kung University Hospital and Dou liou Branch, Tainan, Taiwan, Republic of China
Lupus 19:1204-9. 2010..Critical information from analyses of the present large series could be applied into clinical practices to reduce the morbidity and mortality in such patients...
